A5068745034- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Gynecological conditions and treatments
- Reproductive System and Pregnancy
- Endometrial and Cervical Cancer Treatments
- Intestinal and Peritoneal Adhesions
- Ovarian cancer diagnosis and treatment
- Estrogen and related hormone effects
- Sphingolipid Metabolism and Signaling
- Menstrual Health and Disorders
- TGF-β signaling in diseases
- Reproductive Health and Contraception
- Pregnancy and Medication Impact
- Pain Management and Opioid Use
- Apelin-related biomedical research
- Anesthesia and Pain Management
- Nausea and vomiting management
- Hormonal Regulation and Hypertension
- Vasculitis and related conditions
- Otitis Media and Relapsing Polychondritis
- Pregnancy-related medical research
- Ocular Diseases and Behçet’s Syndrome
- Ectopic Pregnancy Diagnosis and Management
- Sexual function and dysfunction studies
- Protein Tyrosine Phosphatases
University of Florence
2013-2024
Ospedale Sacro Cuore Don Calabria
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2024
Saudi Heart Association
2017
Primary dysmenorrhea (PD) is the most common gynecologic disorder during adolescence and it characterized by crampy lower abdominal pain that occurs menstruation. Secondary dysmenorrhea, in contrast, has same clinical features but women with a disease could account for their symptoms (endometriosis, adenomyosis, uterine fibroids, pelvic inflammatory disease). Endometriosis cause of secondary should be considered patients persistent clinically significant despite treatment. It often diagnosed...
Deep endometriosis (DE) can be localized in the parametrium, a complex bilateral anatomical structure, sometimes necessitating intricate surgical intervention due to potential involvement of autonomic nerves, uterine artery, and ureter. If endometriotic ovarian cysts have been considered metaphorically representative "the tip iceberg" concerning concealed DE lesions, it is reasonable assert that parametrial lesions should construed as most profound region this iceberg. Also, based on subdual...
Endometriosis is a gynecological disease characterized by pain and infertility. The diagnosis very often made during the infertility work-up, together with other reproductive diseases uterine disorders. A retrospective cohort study was conducted on infertile women clinical or ultrasound suspect of endometriosis, undergoing an (US) evaluation team expert sonographers (n = 419), aim to evaluate prevalence concomitant US coexistence endometriosis fibroids and/or adenomyosis investigated...
To study the molecular mechanisms involved in appearance of fibrotic trait endometriosis by investigating whether signaling pathway bioactive sphingolipid sphingosine 1-phosphate (S1P) was altered endometriotic lesions.Case-control laboratory study.University research institute and university hospital.A total 75 women, with without endometriosis, were included study.Endometrial samples obtained from women affected (n = 15 endometrioma [OMA]; n 30 deep infiltrating [DIE]) not 30) means...
Adenomyosis is a common benign uterine disorders and patients may present dysmenorrhea, dyspareunia, abnormal bleeding (AUB) infertility. The treatment very complex, including medical, surgical or radiological approaches. Hormonal drugs represent the first line therapy of adenomyosis, highly effective on symptoms volume reduction. Radiological procedures (UAE HIFU), RFA hysteroscopy be proposed in those cases which medical ineffective. Considering treatment, hysterectomy remains only...
Diaphragmatic endometriosis (DpE) is a rare disease localization which represents an important clinical challenge. The main criticisms toward the proper DpE management consist of poor consensus on both surgical indications and choice between different techniques available to treat disease. Furthermore, only weak recommendations are provided by current guidelines mostly based surgeon's experience. As consequence, lack standardization about treatment led risk under- or over-treatments in...
Abstract Purpose of the Review The purpose this review is to provide a synopsis all mechanisms involved in pathogenesis adenomyosis. It will summarize recent advances field, discussing current controversies, and considering potential future directions. Recent Findings Adenomyosis still topic under investigation, however advancements understanding disease development have been made. New data coming from new next generation sequencing-based studies more-in-depth acquisitions on sex hormones...
Abstract An observational cross-sectional study was conducted in a group ( n = 371) of fertile age women with endometriosis, by administering structured questionnaire, order to evaluate the incidence gynecological and systemic comorbidities impact on quality life (QoL) two different groups Italian Chinese patients affected endometriosis. 175) 196) were compared regarding (inflammatory, autoimmune, mental) comorbidities, pain symptoms, QoL, using Short Form 12 (SF-12). resulted younger at...
Abstract We report a rare case of rectus abdominis muscle endometriosis excised under ultrasound guidance. A 36‐year‐old woman came to our observation presenting an abdominal nodule located in the right side umbilical area. Ultrasound wall showed two hypoechogenic nodules context and fine‐needle aspiration, performed guidance, confirmed diagnosis endometriosis. The patient underwent surgical excision lesions. Intraoperative localization was through ultrasonography. In case, essentially based...
Objectives: Endometriosis is an inflammatory disease characterized by a frequent association with gynecologic and systemic comorbidities. Our aim was to evaluate which comorbidities occur in women affected endometriosis their impact on quality of life global health. Mechanism: A literature search the PubMed, Cochrane Library, Scopus Web Science databases performed identify relevant studies published before December 31, 2021. We selected clinical studies, systematic reviews, meta-analyses...
To evaluate the different effects of a progestin-only contraceptive with desogestrel (DSG) vs combined oral contraceptives (COCs) for first line long-term treatment endometriosis-related pain among patients seeking hormonal contraception.
Background/Objectives Bowel endometriosis (BE) is defined as the presence of endometrial-like tissue in muscular layer bowel wall. When BE does not cause severe obstruction to fecal transit, leading (sub)occlusive symptoms, decision operate becomes challenging intestinal surgery associated with higher complication rates and long-term dysfunction. The aim this cross-sectional study evaluate quality life (QoL) patients undergoing medical therapy or expectant management, investigating impact...
The relationship between endometrioma and ovarian cancer is a topic of discussion in the field endometriosis to date it still debated whether may represent risk factor for cancers.A literature search was carried out using Cochrane Library, EMBASE, Medline Google Scholar up October 2020. Primary outcome interest incidence patients with endometriosis. Secondary prognosis compared patient without endometriosis.Patients has slight increase developing (merely 1.8%), being general population...