A5049893539- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- Preterm Birth and Chorioamnionitis
- Congenital Anomalies and Fetal Surgery
- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Pregnancy-related medical research
- Maternal and Perinatal Health Interventions
- Neonatal and fetal brain pathology
- Birth, Development, and Health
- Tracheal and airway disorders
- Maternal and fetal healthcare
- Ectopic Pregnancy Diagnosis and Management
- Cardiovascular Issues in Pregnancy
- Autopsy Techniques and Outcomes
- Urological Disorders and Treatments
- Abdominal Trauma and Injuries
- Gestational Diabetes Research and Management
- Reproductive System and Pregnancy
- Fetal and Pediatric Neurological Disorders
- Ultrasound Imaging and Elastography
- Congenital Heart Disease Studies
- Pediatric Urology and Nephrology Studies
- Pediatric health and respiratory diseases
Martin Luther University Halle-Wittenberg
2015-2024
University Hospital in Halle
2013-2023
Luther University
2015-2021
Universitätsklinik für Frauenheilkunde und Geburtshilfe
2013-2021
Frauenklinik Heidelberg
2016
Klinik für Frauenheilkunde
2002-2015
Charité - Universitätsmedizin Berlin
2012
Walter de Gruyter (Germany)
2012
Johannes Gutenberg University Mainz
2008-2011
University Medical Center of the Johannes Gutenberg University Mainz
2009-2011
Abstract It has been demonstrated with invasive techniques in fetal lambs that the ratio of ductus venosus to umbilical vein blood flow rate (DV/UV ratio) increases during hypoxemia and infusion catecholamines. Recently it was found human fetuses using pulsed wave Doppler ultrasound equipment DV/UV intra‐uterine growth restriction significantly increased. The aim present study show whether routine devices were capable determining sufficient reliability. experiments performed on seven...
Abstract Objective To assess outcome after fetoscopic laser coagulation (FLC) of placental vascular anastomoses with the 30° fetoscope in mid‐trimester severe twin‐to‐twin transfusion syndrome (TTTS) completely anterior placenta compared regular 0° TTTS other locations. Methods This was a prospective study 176 consecutive monochorionic twin pregnancies undergoing FLC for TTTS. Of these, 51 patients required use (study group) and 125 locations permitted (controls). Results The two groups had...
Acute respiratory infections (ARIs) are the most common childhood illnesses worldwide whereby reported frequency varies widely, often depending on type of assessment. Symptom diaries a powerful tool to counteract possible under-reporting, particularly milder infections, and thus offer possibility assess full burden ARIs. The following analyses based symptom from participants German birth cohort study LoewenKIDS. Primary included frequencies ARIs specific symptoms. Factors, which might be...
Bacterial infection is one of the main causes preterm premature rupture membranes (PPROM) leading to delivery, pulmonary hypoplasia, sepsis and joint deformities. Expectant management, broad-spectrum antibiotics antenatal corticosteroids are routinely used in this condition with very limited success prevent bacteremia, chorioamnionitis, funisitis intra-amniotic syndrome. Here, we report a case which attempted treat PPROM at 26+3 weeks gestation anhydramnion colonized by multiresistant...
The elastic properties of circumscribed tissues (e.g., tendons, lymph nodes, prostates, brain tumors) are considerable clinical interest. purpose this study was thus to compare the Intra-/Inter-observer variation and accuracy in vitro point shear wave elastography (pSWE) with that 2D-SWE assess 2D-SWE's precision variable ROI (vROI) incircumscribed objects.Round targets (Elasticity QA Phantom Model 049) were examined for varying degrees stiffness (8, 14, 45, 80 kPa) diameters (20/10 mm)....
This study aims to treat patients with preterm premature rupture of the membranes (PPROM) and anhydramnion using continuous amnioinfusion through a subcutaneously implanted port system.An amniotic fluid replacement system was in seven PPROM starting at 20th week gestation (range, 14-26 weeks) for long-term amnioinfusion. Saline solutions (2 L/day; Jonosteril(®), Sterofundin(®), isotonic NaCl 0.9% solution, lactated Ringer's solution) hypotonic aqueous composition reduced chloride content...
Abstract Background Women have a markedly increased lifetime risk for cardiovascular morbidity and mortality following hypertensive disorders of pregnancy. Arterial stiffness is regarded as target parameter reducing can be modified by lifestyle changes. Methods In prospective, randomised, controlled interventional study, starting 6 weeks postpartum, the effect nutritional intervention combined with an intensive 6-month exercise programme on arterial was investigated means pulse wave velocity...
To determine if intrauterine intraumbilical supplementation with amino acids (AA) and glucose can improve neonatal outcome of severe growth restricted human fetuses (IUGR).Prospective pilot study treatment IUGR [n=14, 27 weeks gestation (range 23-31)] cerebroplacental ratio <1, long-term AA (10% feto-placental blood volume/day) using a perinatal port system alone (n=5) or combined hyperbaric oxygenation (n=1, HBO) vs. control group (n=8).The duration continuous AA/glucose was 11 (6-13) days....
<i>Objective:</i> Intrauterine growth restriction (IUGR) carries an increased risk of mortality and morbidity. The accepted procedure to treat IUGR fetuses is premature delivery, which may increase neonatal morbidity retards brain development. <i>Material Methods:</i> We report here on intravascular supplementation with amino acids glucose human fetus at 33 weeks gestation oligohydramnios placental insufficiency using the port system (Norfolk Medical Products, Skokie,...
Objective: To improve neonatal outcome using ultrathin fetoscope for laser treatment of twin-to-twin transfusion syndrome.
Objective: Acute hypoxia is one of the main causes poor neonatal outcome. The aim this study was investigation cardiac output (CO) and blood flow redistribution following induction acute in a fetal sheep model.
Abstract Aim: We used positron emission tomography (PET) with radioactive glucose (F‐18‐Fluor‐Deoxglucose [FDG]) to investigate whether acute maternal hypoxemia causes alterations of uptake fetal organs and the placenta. Material Methods: Investigation was performed under normal conditions in 16 sheep between 108 130 days gestation. Maternal were ventilated 1.0–1.5% isoflurane/O 2 /N O during whole scanning procedure. Acute hypoxia induced by reducing a gas mixture achieve arterial...
To establish by Doppler ultrasound the effects of acute blockage umbilical cord vessels on fetal central circulation.Experimental study in anesthetized pregnant sheep.In 11 sheep (0.66 gestation), velocity profiles and/or venous flow rates were recorded ductus venosus, aorta, arteries and vein. This involved three phases. In Phase 1, abdominal wall was closed (n = 9); 2 during fetoscopy after laparotomy 8); 3 coagulation one 10). As an additional intervention six fetuses, clamped for 5-15 s...
<i>Objective:</i> The most common complication of intrauterine tracheal balloon occlusion is the preterm premature rupture membranes (PPROM) which increases rate neonatal morbidity and mortality. Ultrathin fetoscopy may be a method reducing risk PPROM. <i>Materials Methods:</i> operation was performed at 27th week gestation after sedation relaxation fetus with bilateral congenital diaphragmatic hernia liver lifted upwards into thorax. An ultrathin sheath 1.2-mm...