A5112169169- Occupational and environmental lung diseases
- Pesticide Exposure and Toxicity
- Air Quality and Health Impacts
- Indoor Air Quality and Microbial Exposure
- Carcinogens and Genotoxicity Assessment
- Occupational exposure and asthma
- Insect and Pesticide Research
- Contact Dermatitis and Allergies
- Musculoskeletal pain and rehabilitation
- Pesticide and Herbicide Environmental Studies
- Odor and Emission Control Technologies
- Advanced Chemical Sensor Technologies
- Pregnancy and preeclampsia studies
- Occupational Health and Safety Research
- Heavy Metal Exposure and Toxicity
- S100 Proteins and Annexins
- Semiconductor materials and devices
- Effects and risks of endocrine disrupting chemicals
- Asthma and respiratory diseases
- Ergonomics and Musculoskeletal Disorders
- Anesthesia and Neurotoxicity Research
- Allergic Rhinitis and Sensitization
- Toxic Organic Pollutants Impact
- Effects of Vibration on Health
- Environmental Toxicology and Ecotoxicology
Japan Society for Occupational Health
2022-2025
University of Occupational and Environmental Health Japan
2011-2024
Yokkaichi Nursing and Medical Care University
2021-2024
Dokkyo Medical University
2024
Aichi Medical University
2014-2023
University of Yamanashi
2019
Daido University
2013
Khyber Teaching Hospital
2012
Hyogo Medical University
2012
King Saud University
2012
Organophosphate esters are used as additives in flame retardants and plasticizers, they ubiquitous the indoor environment. Phosphorus (PFRs) present residential dust, but few epidemiological studies have assessed their impact on human health. We measured levels of 11 PFRs floor dust multi-surface 182 single-family dwellings Japan. evaluated correlations with asthma allergies inhabitants. Tris(2-butoxyethyl) phosphate was detected all samples (median value: 580 μg/g 111 dust)....
This study aims at clarifying the semen indices of insecticide sprayers who are exposed mainly to organophosphorus and pyrethroid insecticides. Eighteen male out 54 working for 9 companies in central Japan 18 age-matched students or medical doctors as unexposed controls participated detailed reproductive check-ups conducted summer following winter. The were insecticides more summer, busiest season, than winter, off-season (p<0.05). Erythrocyte true cholinesterase activities lower (p<0.05),...
This study was conducted to clarify regional differences in residential factors and the association of those with dwellings having sick house syndrome (SHS) problems. The survey six areas northern southern Japan. In terms differences, dampness not as severe Sapporo compared that south. SHS defined using five categories nasal, throat respiratory, skin general symptoms, which appeared frequently or improved upon leaving home. index estimated by sum presence several indicators: condensation on...
1-Bromopropane has been newly introduced as an alternative to ozone layer-depleting solvents. We aimed clarify the dose-dependent effects of 1-bromopropane on nervous system. Forty-four Wistar male rats were randomly divided into 4 groups 11 each. The exposed 200, 400, or 800 ppm only fresh air 8 h per day for 12 weeks. Grip strength forelimbs and hind limbs, maximum motor nerve conduction velocity (MCV), distal latency (DL) tail measured in 9 each group every other 2 perfused at end...
1-Bromopropane has been newly introduced as an alternative to ozone-depleting solvents. We aimed clarify its dose-dependent reproductive toxicity in male rats. Thirty-six Wistar rats were randomly divided into 4 groups of 9. The exposed 200, 400, or 800 ppm 1-bromopropane only fresh air, 8 h per day for 12 weeks. Epididymal sperm indices evaluated after a 12-week exposure. testes, epididymides, seminal vesicle, prostate, and other organs weighed examined histopathologically. Spermatogenic...
The 1,4-dihydropyridine (DHP) Ca2+ antagonists and agonists can inhibit a time- voltage-dependent, but intracellular Ca(2+)-independent transient outward K+ current (It), in myocytes from rabbit atrium. In the presence of 0.3 mM CdCl2, DHPs decreased peak It slightly markedly accelerated its apparent rate inactivation. When inhibition was measured integrated records, 50% inhibitory concentrations (IC50) nicardipine BAY K 8644 were 630 nM 7 microM, respectively, IC50 for (ICa) only...
We reported recently that 1-bromopropane (1-BP; n-propylbromide, CAS Registry no. 106-94-5), an alternative to ozone-depleting solvents, is neurotoxic and exhibits reproductive toxicity in rats. The four most recent case reports suggested possible neurotoxicity of 1-BP workers. aim the present study was establish neurologic effects workers examine relationship with exposure levels. surveyed 27 female a production factory compared 23 them age-matched beer as controls. were interviewed...
Idiosyncratic generalized skin disorders complicated by hepatitis, which resemble severe drug hypersensitivities, occur sporadically in workers exposed to trichloroethylene (TCE) China. However, it has been a matter of controversy whether the solvent itself, not its impurities or stabilizers, can cause hypersensitivity reactions not. This study aimed characterize exposure hospitalized patients and their healthy colleagues. TCE metabolites were measured urine 19 suffering from disorders. To...
Biological Monitoring of Pyrethroid Exposure Pest Control Workers in Japan: Dong W ang , et al . Department Radiological and Medical Laboratory Sciences, Nagoya University Graduate School Medicine —Synthetic pyrethroids such as cypermethrin, deltamethrin permethrin, which are usually used pest control operations, metabolized to 3‐phenoxybenzoic acid (3‐PBA) excreted urine. Though 3‐PBA can be assess exposure pyrethroids, there few reports describing urinary levels Japan. This study aimed...
SummaryThe hepatic synthesis of cholesterol has been studied in the rat at different ages, using a biliary concentration as an index this factor. The results suggest that depends upon age animal, with considerably greater younger rat.
Lifelong health is dependent on prenatal growth and development, influenced by the placental intrauterine environment. Charged with dual functions--exchange of oxygen nutrients as well a barrier against toxins--the placenta itself susceptible to environmental exposure heavy metals.