- Cholesterol and Lipid Metabolism
- Biochemical Analysis and Sensing Techniques
- Consumer Attitudes and Food Labeling
- Phytochemicals and Antioxidant Activities
- Fermentation and Sensory Analysis
- Horticultural and Viticultural Research
- Microbial Inactivation Methods
- Fatty Acid Research and Health
- Seed and Plant Biochemistry
- Food composition and properties
- Lipid Membrane Structure and Behavior
- Postharvest Quality and Shelf Life Management
- Agriculture Sustainability and Environmental Impact
- Advances in Cucurbitaceae Research
- Metabolomics and Mass Spectrometry Studies
- Atherosclerosis and Cardiovascular Diseases
- Botanical Research and Applications
- Nutrition, Health and Food Behavior
- Nutritional Studies and Diet
- Birth, Development, and Health
- Antioxidant Activity and Oxidative Stress
- Dye analysis and toxicity
- Microbial Metabolites in Food Biotechnology
- Magnetic and Electromagnetic Effects
- Protein Structure and Dynamics
Michigan State University
2017-2024
Michigan Department of Agriculture and Rural Development
2022-2024
University of Michigan
2024
University of Kansas
2024
University of Agriculture Faisalabad
2023
H-Net: Humanities & Social Sciences Online
2023
Washington State University
2013-2016
Instituto Tecnologico de Veracruz
2011
Quinoa (Chenopodium quinoa Willd) contains 2 to 5% saponins in the form of oleanane-type triterpenoid glycosides or sapogenins found external layers seeds. These confer an undesirable bitter flavor. This study maps content and profile glycoside-free from 22 varieties 6 original breeding lines grown North America under similar agronomical conditions. Saponins were recovered using a novel extraction protocol quantified by GC-MS. Oleanolic acid (OA), hederagenin (HD), serjanic (SA),...
In response to the imperative address food and agricultural waste promote environmental sustainability, this study investigates transformation of watermelon rind into a valuable resource. We extract polyphenols antioxidants from freeze-dried across four cultivars (Crimson Sweet, Black Prince, Chairman, Sugar Baby) using ultrasound-assisted extraction. Solvent selection, based on preliminary experiment, was optimized through surface methodology (RSM), fine-tuning solvent concentration...
Abstract Although membrane environment is known to boost drug metabolism by mammalian cytochrome P450s, the factors that stabilize structural folding and enhance protein function are unclear. In this study, we use peptide‐based lipid nanodiscs “trap” boundaries of microsomal P450 2B4. We report first evidence CYP2B4 able induce formation raft domains in a biomimetic compound endoplasmic reticulum. NMR experiments were used identify quantitatively determine lipids present nanodiscs. A...
The average American consumes more than 50% of their total dietary energy from ultra-processed foods (UPFs). From a nutritional standpoint, as UPFs intake increases, fiber, vitamin, and mineral decrease. High consumption UPFs, mainly fast (FF) ready-to-eat (RTE) food items, emerges critical public health concern linking quality safety. In the present work, systematic database fatty acid composition most consumed in Midwest is reported. Saturated monounsaturated acids were predominant RTE...
Abstract Extrusion of 2 quinoa varieties, Cherry Vanilla and Black (scarified unscarified) a mixed variety, Bolivian Royal degermed) were studied for their extrusion characteristics. A corotating twin‐screw extruder with 3 mm round die was used. Feed moisture contents 15%, 20%, 25% (wet basis) studied. The barrel temperature kept constant at 140 °C screw speeds varied from 100, 150, 200 revolutions per minutes. Process responses (specific mechanical energy, back pressure, torque) product...
Removal of basal leaves near blooms inevitably affects grapevine balance and cluster microclimate conditions, improving fruit quality. Mechanization this practice allows growers to save time resources, but our knowledge, it has not yet been compared with the manual application in a cool-climate region where seasonal temperatures frequently limit technological maturity phenolic ripening red Vitis vinifera cultivars. In research, berry sugar concentration was highest prebloom mechanical...
Ultra-processed foods (UPFs) have gained substantial attention in the scientific community due to their surging consumption and potential health repercussions. In addition well-established poor nutritional profile, UPFs been implicated containing various dietary oxidized sterols (DOxSs). These DOxSs are associated with a spectrum of chronic diseases, including cardiometabolic conditions, cancer, diabetes, Parkinson's, Alzheimer's disease. this study, we present comprehensive database...
The use of high pressure on fruits and vegetables is today widely studied as an alternative to the traditional thermal preservation techniques, with aim better preserving nutritional organoleptic properties. hydrostatic pressures (400-600 MPa; 1-5 min; room temperature) was tested physicochemical structural properties blueberries, in comparison raw blanched samples. High led higher tissue damages than blanching, related intensity treatment. cellular resulted leakage intracellular components,...
Lipids are critical for the function of membrane proteins. NADPH-cytochrome-P450-reductase, sole electron transferase microsomal oxygenases, possesses a conformational dynamics entwined with its topology. Here, we use peptide-nanodiscs to unveil cytochrome-P450-reductase's lipid boundaries, demonstrating protein-driven enrichment ethanolamine lipids (by 25%) which ameliorates by 3-fold CPR's electron-transfer ability.
Cancer and atherosclerosis share common risk factors inflammatory pathways that promote their proliferation via vascular endothelial growth factor (VEGF). Because CCs cause mechanical injury inflammation in atherosclerosis, we investigated presence solid cancers activation of IL-1β, VEGF, CD44, Ubiquityl-Histone H2B (Ub-H2B), cancer growth.Tumor specimens from eleven different types human atherosclerotic plaques were assessed for CCs, free cholesterol content IL1-β by microscopy,...
FooDOxS is a large database of dietary oxidized sterols (DOxS), cholesterol-like molecules known to exert pro-inflammatory, pro-oxidant, and pro-apoptotic effects in humans.
As the demand for grass-fed ruminant products keeps increasing, more data are needed to assess nutritional value of feedstuffs, especially pastures. In addition, global climate change adds another challenge management grasslands with projections changing temperature and precipitation patterns. Consequently, variations in bioactive compounds such as fatty acids antioxidants feeds will be harder predict. Therefore, it is critical report region time-specific results intended nutrition. The...
Abstract In response to the market demand for low processed vegetables, high-pressure treatments (400,600 MPa; 1,5 min) were applied on zucchini slices and compared a traditional blanching treatment. Histological observations, texture color analysis, pectinmethylesterase (PME) antioxidant (DPPH) activities measured untreated samples. The histological observations revealed that longer (5 led more extended cell lysis dehydration than shorter ones (1 blanching. High-pressure resulted less...