A5086730032- Photosynthetic Processes and Mechanisms
- Protist diversity and phylogeny
- Research Data Management Practices
- Microbial Community Ecology and Physiology
- Algal biology and biofuel production
- Big Data and Business Intelligence
- Intelligence, Security, War Strategy
- bioluminescence and chemiluminescence research
- Scientific Computing and Data Management
- Semantic Web and Ontologies
- Geological Modeling and Analysis
- Mitochondrial Function and Pathology
- Metal-Catalyzed Oxygenation Mechanisms
- Advanced Computational Techniques and Applications
- Light effects on plants
- Coastal wetland ecosystem dynamics
- Hemoglobin structure and function
- Power Systems and Technologies
- Photoreceptor and optogenetics research
- Historical Geography and Cartography
- Satellite Image Processing and Photogrammetry
- Enzyme Structure and Function
- Scientific Research and Discoveries
- Scientific Research and Philosophical Inquiry
- Genomics and Phylogenetic Studies
Digital Science (United States)
2022
University of Cambridge
2002-2018
Medical Research Council
2007
MRC Human Nutrition Research
2007
Philipps University of Marburg
1999-2000
Institute for Marine Biosciences
2000
Canadian Institute for Advanced Research
2000
University of British Columbia
2000
Cells of several major algal groups are evolutionary chimeras two radically different eukaryotic cells. Most these “cells within cells” lost the nucleus former endosymbiont. But after hundreds millions years cryptomonads still retain their red endosymbiont as a tiny relict organelle, nucleomorph, which has three minute linear chromosomes, but function and nature ends have been unclear. We report extensive cryptomonad nucleomorph sequences (68.5 kb), from one end each chromosomes Guillardia...
The UK has a long-established reputation for excellence in research across broad range of fields, but recent years, there been greater emphasis on STEM investment and recognition the UK's success STEM. This paper examines relative strengths SHAPE disciplines demonstrates that portfolio outperforms research, each international benchmark considered this work. It is argued becoming increasingly important as partner to widespread use technology creates societal challenges. also strength basis...
Complex plastids, found in many alga groups, are surrounded by three or four membranes. Therefore, proteins of the complex which encoded cell nucleus, must cross membranes during transport to plastid. To study this process we have developed a method for isolating transport-competent two membrane-bound plastids derived from cryptophyte Guillardia theta. This vitroprotein import system provides first non-heterologous studying into four-membrane plastids. We use our as well canine microsomes...
Cytochrome c6A is a unique dithio-cytochrome of green algae and plants. It has very similar core structure to that bacterial algal cytochromes c6 but unable fulfill the same function transferring electrons from cytochrome f photosystem I. A key feature its heme midpoint potential more than 200 mV below despite having His Met as axial heme-iron ligands. To identify molecular origins difference in potential, cyanobacterium Phormidium laminosum been determined by X-ray crystallography compared...
This report highlights the growth in research around UN’s Sustainable Development Goals (SDGs). We believe SDGs are now more relevant than ever, for they provide a framework recovery from current pandemic.In we ask, if to have an impact agenda research, should it not be one that is informed by SDGs? And so, actively measuring sustainable development as part of evaluation?
We analyzed a eukaryotically encoded rubredoxin from the cryptomonad Guillardia theta and identified additional domains at N- C-termini in comparison to known prokaryotic paralogous molecules. The cryptophytic N-terminal extension was shown be transit peptide for intracellular targeting of protein plastid, whereas C-terminal domain represents membrane anchor. Rubredoxin all tested phototrophic eukaryotes. Presumably facilitated by its extension, nucleomorph-encoded (nmRub) is associated with...
We have identified an open reading frame with homology to prokaryotic rubredoxins (rds) on a nucleomorph chromosome of the cryptomonad alga Guillardia theta . cDNA analysis let us propose that rd preprotein has NH 2 ‐terminal extension functions as transit peptide for import into plastid. Compared rds found in non‐photosynthetic prokaryotes or bacteria exhibit anoxigenic photosynthesis apparatus, COOH‐terminal extension, which shows high exclusively COOH‐termini cyanobacterial well...
Research funders and research organisations both require feedback on the progress, productivity quality of they support. This information originates with researchers, but may be captured in a variety systems including University CRIS/IR funder systems. In 2014 all 7 national Councils (collectively referred to as RCUK) implemented harmonised approach collection output data, currently supported by Researchfish Ltd (referred Researchfish® system). 2016 this process is gathering from over 60,000...
Chlamydomyxa labyrinthuloides is a heterokont alga known since the last century. It lives on Sphagnum and other water plants as aplanospores or plasmodia. We have investigated taxonomic position of by combining results from morphological studies, pigment analyses molecular phylogenetic analysis small subunit (SSU) rRNA gene. shares features with xanthophytes chrysophytes, whereas composition indicates grouping phaeophytes, raphidophytes chrysophytes. The sequence SSU gene its reconstruction...
Abstract The rubredoxin from the cryptomonad Guillardia theta is one of first examples a encoded in eukaryotic organism. structure soluble zinc‐substituted 70‐residue G. lacking membrane anchor and thylakoid targeting sequence was determined by multidimensional heteronuclear NMR, representing three‐dimensional (3D) rubredoxin. For calculation strategy applied which information about hydrogen bonds directly inferred long‐range HNCO experiment, dynamics protein deduced nuclear Overhauser...
While Research Information continues to mature as an area of expertise, discussions regarding the implementation and adoption standardisation initiatives, such CASRAI CERIF, have intensified. Possessing capacity use a standard does not obligate its adoption, so extent which standards are employed varies across cases institutions, in way that is difficult qualify determine. We presenting light-weight visualisation framework for presenting, comparing improving research information...
Abstract Chlamydomyxa labyrinthuloides is a heterokont alga known since the last century. It lives on Sphagnum and other water plants as aplanospores or plasmodia. We have investigated taxonomic position of by combining results from morphological studies, pigment analyses molecular phylogenetic analysis small subunit (SSU) rRNA gene. shares features with xanthophytes chrysophytes, whereas composition indicates grouping phaeophytes, raphidophytes chrysophytes. The sequence SSU gene its...