A5011062963- Dental Implant Techniques and Outcomes
- Bone Tissue Engineering Materials
- Periodontal Regeneration and Treatments
- Dental materials and restorations
- Dental Radiography and Imaging
- Orthodontics and Dentofacial Orthopedics
- Titanium Alloys Microstructure and Properties
- Orthopaedic implants and arthroplasty
- Supercapacitor Materials and Fabrication
- Advanced Battery Materials and Technologies
- Advanced materials and composites
- Graphene and Nanomaterials Applications
- Aluminum Alloys Composites Properties
- Nanoplatforms for cancer theranostics
- Cleft Lip and Palate Research
- Advancements in Battery Materials
- Mesenchymal stem cell research
- Advanced Technologies in Various Fields
- Nanoparticles: synthesis and applications
- Intermetallics and Advanced Alloy Properties
- Supramolecular Self-Assembly in Materials
- Spine and Intervertebral Disc Pathology
- Neuroscience and Neural Engineering
- Additive Manufacturing Materials and Processes
- dental development and anomalies
Shanghai Jiao Tong University
2014-2025
Shanghai Ninth People's Hospital
2015-2025
Jilin University
2024
National Clinical Research
2019-2024
National Clinical Research Center for Digestive Diseases
2020-2024
Shanghai Stomatological Hospital
2024
Fujian Normal University
1992-2010
Stomatology Hospital
2007
Hierarchical micro/nanostructured titanium with balanced actions to bacterial and mammalian cells for dental implants Yu Zhu,1,* Huiliang Cao,2,* Shichong Qiao,1,* Manle Wang,2,3 Yingxin Gu,1 Huiwen Luo,1 Fanhao Meng,2 Xuanyong Liu,2 Hongchang Lai1 1Department of Oral Maxillofacial Implantology, Shanghai Key Laboratory Stomatology, Ninth People’s Hospital, School Medicine, Jiao Tong University, 2State High Performance Ceramics Superfine Microstructure, Institute Ceramics, Chinese...
Biomaterial with the dual-functions of bone regeneration and antibacterial is a novel therapy for infective defects. Three-dimensional (3D)-printed porous titanium (pTi) benefits ingrowth, but its microporous structure conducive to bacteria reproduction. Herein, multifunctional hydrogel was prepared from dynamic supramolecular assembly sodium tetraborate (Na 2 B 4 O 7 ), polyvinyl alcohol (PVA), silver nanoparticles (AgNPs) tetraethyl orthosilicate (TEOS), composited pTi as an implant...
Abstract Microorganisms are frequently introduced to dental implants during surgery and start the race for surface with host cells before osseointegration occurs. The aim of study was endow implant surfaces biological functions that reliably select over microbes. Nano‐structured tantalum (Ta) has exhibited excellent compatibility. Thus, nano‐structured Ta films were deposited on sand‐blasted, large grit, acid‐etched (SLA) titanium by magnetron sputtering method, thus forming hierarchical...
Although tantalum (Ta)-based coatings have been proven to good antibacterial activity, the underlying mechanism and in vivo biological performance remain unclear, which are essential for clinical application of Ta-coated biomaterials as dental implants.The main objective this study is investigate activity Ta-modified titanium (Ti) implants against peri-implantitis-related microbes potential molecular mechanisms.Fusobacterium nucleatum Porphyromonas gingivalis were selected evaluate Ta...
The serious complications after arthroplasty in patients with osteoporosis is a challenge for orthopedics. Three-dimensional (3D)-printed porous titanium (pTi) alloys have the character of low stiffness, similar to cortical bone, and are seemed as promising materials orthopedic applications, but limited by bio-inert alloy. Thus, improving bioactivity prosthesis bone regeneration around implant crucial osseointegration. Herein, we established rabbit model bilateral ovariectomy, bioactive...
Abstract Aim Treatment of periodontitis, a chronic inflammatory disease driven by biofilm dysbiosis, remains challenging due to patients' poor performance and adherence the necessary oral hygiene procedures. Novel, artificial intelligence‐enabled multimodal‐sensing toothbrushes (AI‐MST) can guide practices in real‐time transmit valuable data clinicians, thus enabling effective remote monitoring guidance. The aim this trial was assess effect such system as an adjunct clinical practice...
Periodontitis is a chronic inflammatory disease marked by dysregulated immune microenvironment, posing formidable challenges for effective treatment. The characterized an altered glucose metabolism in macrophages, specifically increase aerobic glycolysis, which linked to heightened responses. This suggests that targeting macrophage could offer new therapeutic avenue. In this study, we developed immunometabolic intervention using quercetin (Q) encapsulated bioadhesive mesoporous polydopamine...
Abstract Purpose The aim of the study was to evaluate clinical parameters and patient satisfaction treatments with short implants compared longer osteotome sinus floor elevation (OSFE) in atrophic posterior maxillae. Materials Method data were retrieved from an ongoing randomized controlled trial (NCT02350075). Patients randomly allocated into three groups: (group1: short‐6 mm implant, group 2: short‐8‐mm implant OSFE, 3: standard‐10 OSFE). Early failure, complications, stability quotient...
Abstract Objectives This study aims to evaluate the ability of tantalum-coated titanium improve human gingival fibroblasts’ adhesion, viability, proliferation, migration performance, and potential molecular mechanisms. Materials methods Titanium plates were divided into two groups: (1) no coating (Ti, control), (2) Tantalum-coated (Ta-coated Ti). All samples characterized by scanning electronic microscopy, surface roughness, hydrophilicity. Fibroblasts’ performance analyzed attached cell...
Abstract Aim To evaluate implant stability and histological outcomes after osteotome sinus floor elevation ( OSFE ) procedure, to compare new bone formation osseointegration with without grafting. Material methods simultaneous placement was conducted bilaterally on 6 Labrador dogs. Twenty‐four implants were placed. The right side (Group 1) grafted biphasic calcium phosphate BCP ), whereas the left 2) any grafting materials. animals euthanized 8 24 weeks surgery for histomorphometric...
Abstract Purpose To evaluate the long‐term aesthetic outcome of single crowns supported by soft tissue level implants placed in healed sites anterior maxilla region via pink score ( PES ) and white WES ). Material methods According to inclusion criteria, patients who had received a Straumann ® Standard Plus implant at Shanghai 9th People's Hospital between 2005 2008 were invited for re‐examination based on number criteria exclusion criteria. Clinical, radiographic outcomes / assessed during...
Abstract Background Titanium‐zirconium alloy (TiZr1317) is a new material used for biological implants. There are several studies on the effects of TiZr implants characteristics human bone mesenchymal stem cells (hBMSCs). Purpose The purpose this study was to investigate responses hBMSCs implant holes affected by physicochemical properties oral (Ti SLA , Ti SLActive and ). Materials Methods Grade 4 (13‐17% Zr) substrates were modified sand‐blasted large‐grit acid‐etched (SLA) or hydrophilic...