A5001361877- bioluminescence and chemiluminescence research
- Nanoplatforms for cancer theranostics
- Cancer Research and Treatments
- Photoacoustic and Ultrasonic Imaging
- Polyamine Metabolism and Applications
- Photodynamic Therapy Research Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Cell Image Analysis Techniques
- Plant tissue culture and regeneration
- Amino Acid Enzymes and Metabolism
- Nanoparticles: synthesis and applications
- Advanced Nanomaterials in Catalysis
- Biomarkers in Disease Mechanisms
- Molecular Communication and Nanonetworks
- Phytochemicals and Antioxidant Activities
- Pancreatic function and diabetes
- Epigenetics and DNA Methylation
- Monoclonal and Polyclonal Antibodies Research
- Skin Protection and Aging
- Pharmacogenetics and Drug Metabolism
- Mass Spectrometry Techniques and Applications
- 3D Printing in Biomedical Research
- Advanced MRI Techniques and Applications
- Natural product bioactivities and synthesis
- Silicon Nanostructures and Photoluminescence
Centre National de la Recherche Scientifique
2008-2012
Pierre Fabre (France)
2009-2012
Université d'Orléans
2011-2012
Université Toulouse III - Paul Sabatier
2011
Inserm
2011
Laboratoire Pluridisciplinaire de Recherche en Ingénierie des Systèmes, Mécanique et Energétique
2011
Pierre Fabre (Germany)
2010
Transgene (France)
2009
Centre National pour la Recherche Scientifique et Technique (CNRST)
2008
Imagerie et Cerveau
2008
Abstract This work was conducted to evaluate the potential antitumor effect of an in vivo plasma treatment on a U87‐luc glioma tumor. A pulsed DBD with µs pulses at moderate power used for treatment. Electrical analyses and spectroscopic measurements were realized characterize properties. We showed that safe mice. However, reiterated long time (20 min, 3 consecutive days) produces superficial burn. During treatment, we observed increase subcutaneous temperature cutaneous skin pH reduction....
Skin cancer is a global health issue and mainly composed of melanoma nonmelanoma cancers. For the first clinical proof concept on humans, we decided to study good prognosis skin cancers, i.e., carcinoma basal cell. In UE, first-line treatment remains surgical resection, healing most tumors, but presents aesthetic disadvantages with high reoccurrence rate exposed areas. Moreover, therapeutic indications could extend metastasis, which different medical strategy that combine this treatment....
This article compares the performance of target detectors based on adaptive background differencing public benchmark data. Five state art methods are described. The is evaluated using measures with respect to ground truth. original points comparison hand labelled truth and evaluation a large database. simpler LOTS SGM more appropriate particular task as MGM complex model.
The assessment of anticancer agents to treat leukemia needs have animal models closer the human pathology such as implantation in immunodeficient mice leukemic cells from patient samples. A sensitive and early detection tumor these orthotopic is a prerequisite for monitoring engraftment their dissemination mice. Therefore, we developed fluorescent antibody based strategy detect foci bearing patient-derived using fluorescence reflectance imaging (FRI) determine when start treatments with...
The data presented in this article are related to the research paper "Proof of concept plasmonic thermal destruction surface cancers by gold nanoparticles obtained green chemistry" (Ben Hadadda et al, 2019). In article, we examined murine melanoma using chemistry. were measuring tumor volume and mice weight different groups B16F10 treated or not with coupled laser irradiation. These compared clinical reference treatment: anti-PD1 monoclonal antibody. analyzed order be able compare antitumor...
Abstract Background Basal cell carcinoma (BCC) is the most common form of skin cancer, typically developing in sun‐exposed areas such as face. Surgery treatment choice, with a overall good prognosis. However, some scars can be unsightly or bothersome, and tumours are too large badly located to eligible for surgery. Plasmonic photothermal therapy presented here an alternative treatment. Our team has developed green gold nanoparticles that have demonstrated their efficacy inducing hyperthermia...
To improve spatial resolution in vivo bioluminescence imaging, a photon scattering correction, image restoration method was tested. The chosen algorithm tested on bioluminescent images acquired three representative tumor models: subcutaneous, pulmonary, and disseminated peritoneal. Tumor size as quantitative criterion, such that the reference measurements (determined photographically or by computed tomography) were compared to those derived from images, before after restoration. This...
In this work, phytochemical components, and the antioxidant properties of an aqueous extract obtained from a medicinal plant Hubertia ambavilla, endemic to Reunion Island, were investigated. A total 37 compounds detected identified by high-performance liquid chromatography (UHPLC) using photodiode-array detector (DAD) coupled with electrospray ionization/mass spectrometry (ESI/MSn ). From calibration curves, quantity secondary metabolites in was calculated. The mean amounts phenols,...
Background/Objectives: Metallic nanoparticles (NPs) exhibit interesting radiosensitizing effects, and finding a way to accurately deliver them appears be crucial. Due their tumor tropism, mesenchymal stem cells (MSCs) represent strategic approach. Therefore, we aimed evaluate the impact of core–shell Fe3O4@Au NPs on functionality human pulmonary MSCs (HPMSCs). Methods/Results: The results showed that 100 µg/mL NPs, accumulated in HPMSCs (revealed by Prussian blue staining), did not alter...
Abstract Significance Multilesional basal cell carcinoma (BCC) are spread on sun exposed skin areas, including arms, face and back. The first‐line treatment remains the surgical resection or Mohs surgery. Despite its high complexity, surgery is well practiced in USA Germany presents very good results both esthetic carcinology point of view. Large lesions more than 2 cm remain challenging to remove by topical cream used photodynamic therapy (PDT). If these larger not treated less 1 month,...
Abstract Despite advances in the therapy of acute myeloid leukemia (AML), majority patients die from their disease. Therefore, lack effective mandates development novel compounds to improve outcome with relapsed and refractory leukemias. F14512 is a potent spermine-epipodophyllotoxin conjugate exploiting polyamine transport system for tumor cell delivery. In this study, we report vivo antitumor activity against experimental models AML lines patient samples. markedly reduced growth HL-60 U937...