A5103120598- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Pneumothorax, Barotrauma, Emphysema
- SARS-CoV-2 and COVID-19 Research
- Sepsis Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Drug-Induced Adverse Reactions
- COVID-19 and Mental Health
- Muscle and Compartmental Disorders
- COVID-19 Impact on Reproduction
- Antifungal resistance and susceptibility
- Cerebrospinal fluid and hydrocephalus
- Autoimmune Bullous Skin Diseases
- COVID-19 and healthcare impacts
- Bone Tumor Diagnosis and Treatments
- Cardiac tumors and thrombi
- Trauma Management and Diagnosis
- Lipid metabolism and disorders
- Spinal Dysraphism and Malformations
- Heparin-Induced Thrombocytopenia and Thrombosis
- Sarcoma Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- SARS-CoV-2 detection and testing
- Renal function and acid-base balance
Hamad Medical Corporation
2018-2025
META Group
2025
Analysis Group (United States)
2025
Idlib University
2024
Hamad General Hospital
2020-2024
Weatherford College
2022-2023
Ministry of Public Health
2023
Weill Cornell Medical College in Qatar
2020-2023
Development Fund
2022
University College London
2021
Abstract COVID-19 complications still present a huge burden on healthcare systems and warrant predictive risk models to triage patients inform early intervention. Here, we profile 893 plasma proteins from 50 severe mild-moderate patients, healthy controls, show that 375 are differentially expressed in the of patients. These implicated pathogenesis targets for candidate drugs prevent or treat complications. Based proteomics clinical lab tests, also report 12-plasma protein signature model...
Abstract The authors urge clinicians to balance the use of Immunosuppressant drugs and tocilizumab for COVID‐19 patients avoid development infections like Cryptococcemia, leading death within 30 days.
Coronavirus disease 2019 (Covid-19) is an infectious caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It mainly affects the lungs and common symptoms are fever, cough shortness of breath. Pneumothorax has been noted to complicate Covid-19 cases requiring hospital admission, however exact incidence risk factors still unknown.We present a series 3 primary spontaneous pneumothorax with pneumonia. All in our did not require positive pressure ventilation none had any...
The coronavirus disease 2019 (COVID-19) pandemic affected millions of people worldwide resulting in a substantial number hospitalizations. Venous thromboembolism including pulmonary embolism is known complication COVID-19 pneumonia although its incidence such patients unclear. In this multicenter retrospective cohort study, we looked at the and associations with various risk factors demographics, comorbidities, inflammatory markers coagulation profiles. We analyzed data from 193 mixed...
Our work highlights patients at risk of prolonged viral shedding in COVID-19 and its implications for isolation strategies explores possible solution by PCR-CT value testing (cycle threshold value). We also review the impact HIV on COVID-19.
ABSTRACT Background and Aims The neutrophil‐to‐lymphocyte ratio (NLR) is a cost‐effective indicator of inflammation, which may impact decisions regarding therapy for patients undergoing continuous renal replacement (CRRT), even with ongoing clinical arguments. This study aimed to examine the correlation between NLR prognosis critically ill CRRT, specifically about mortality morbidity. Additionally, sought assess NLR's potential as prognostic CRRT initiation. Methods Data were retrospectively...
Despite its pivotal role in drug metabolism, the exact consequences of rising medica-tions count from various therapeutic classes on mortality outcomes amongst patients with chronic liver disease remains unexplored. In this study, we investigated effect different polypharmacy phenotypes clinical including length hospitalization, need for intensive care admission, and (CLD). Methods: This retrospective cohort study examined impact receiving at tertiary centres within Weill Cornell...
COVID-19 patients presenting with ocular manifestations are from 0.8% to 32% of seen in the ED. The available literature is scarce regarding Middle Eastern region.This study aims report incidence signs and symptoms find any correlation between occurrence patients' comorbidities.All having primary diagnosis infection concurrent on admission our tertiary health care centre were included study. patient's demographic data, comorbidities, type recorded records retrospectively.In study, 39 (7.8%)...
Clinical characteristics and factors associated with mortality in patients admitted to the intensive care unit (ICU) countries low case fatality rates (CFR) are unknown. We sought determine these a large cohort of critically ill COVID-19 Qatar explore early predictors.We retrospectively studied clinical outcomes ICU at national referral hospital for Qatar. Logistic regression analysis was used mortality.Between March 7 July 16, 2020, total 1079 were ICU. The median (IQR) age 50 (41-59)...
Background COVID-19 is associated with significant morbidity and mortality. This study aimed to explore the early predictors of intensive care unit (ICU) admission among patients COVID-19. Methods was a case–control adult confirmed Cases were defined as admitted ICU during period February 29–May 29, 2020. For each case enrolled, one control matched by age gender. Results A total 1,560 included. Each group included 780 predominant male gender (89.7%) median 49 years (interquartile range =...
Abstract The authors urge clinicians to observe for early signs of CMV reactivation in patients presenting with gastrointestinal bleeding and intestinal perforation after receiving tocilizumab or other immunosuppressive therapy as a treatment COVID 19. Early recognition infection will prevent life‐threatening mortality.
Abstract Coronavirus disease 2019 (COVID-19) increases the risk of coagulopathy. Although presence antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism COVID-19-induced coagulopathy, its clinical significance remains uncertain. Therefore, this study aimed to evaluate prevalence and aPLs among critically ill patients with COVID-19. This prospective observational included 60 COVID-19 admitted intensive care units (ICU). The outcomes aPLs, primary composite outcome...
The scope of clinical pharmacy services has changed during COVID-19 pandemic with the view to mitigating both exposure and spread virus. performance novel pandemic-driven such as tele-pharmacy remained unexplored, until now. aim this study is investigate perceptions healthcare providers impact provided in critical care units COVID-19.
Abstract Introduction COVID‐19 can occasionally complicate into spontaneous pneumothorax (SP) and/or pneumomediastinum (SM). This study aims at exploring the occurrence of SP and or SM, risk factors, outcomes in patients. Materials Methods All patients with COVID‐19, which complicated SM Hamad Medical Corporation (the principal public healthcare provider Qatar) from March to September 2020, were retrospectively enrolled. The clinical diagnosis was confirmed by CXR CT. Between‐group...
Abstract This case highlights an atypical presentation of a patient with unknown history mental disease who has been diagnosed bipolar disorder associated severe COVID‐19 symptoms. Neuroimaging was only positive for subtle white matter changes; he treated antipsychotics and mood‐stabilizing agents until reached partial remission. The authors urge clinicians to consider the impact pandemic on patients illness urgent need vigilant monitoring presenting signs
The total number of ICU admissions for COVID-19 patients has increased steadily. Based on the research team's clinical observations, many developed rhabdomyolysis, but few cases were reported in literature. This study explores incidence rhabdomyolysis and its outcomes, like mortality, need intubation, acute kidney injury, renal replacement therapy (RRT).We retrospectively reviewed characteristics outcomes admitted to at a COVID-19-designated hospital Qatar between March July 2020. Logistic...
Awake prone position (APP) has been reported to improve oxygenation in patients with COVID-19 disease and reduce the requirement for invasive mechanical ventilation requiring support high flow nasal cannula. There is conflicting data lower-level oxygen support.
Tension pneumomediastinum (TPM) is a rare but potentially fatal clinical entity. TPM leads to the leakage of air into mediastinal cavity and increased pressure in thoracic vessels, respiratory tract, heart. Herein, this report presents series five cases coronavirus disease-2019 (COVID-19) that caused acute distress syndrome (ARDS) TPM. All patients were male who had severe ARDS with secondary lung infection required invasive ventilation moderate positive-end expiratory pressure. vasopressors...
Abstract Background Intravenous immunoglobulin (IVIG) has been used as an immunomodulatory therapy to counteract severe systemic inflammation in coronavirus disease 2019 (COVID-19). But its use COVID-19 related acute respiratory distress syndrome (ARDS) is not well established. Methods We conducted a retrospective analysis of electronic health records patients admitted intensive care units (ICUs) at Hazm Mebaireek General Hospital, Qatar, between March 7, 2020 and September 9, 2020. Patients...
The main aim of this study is to compare the use non-invasive ventilation (NIV) via helmet versus face mask where different interfaces and masks can apply NIV. However, some limitations NIV were air leak, intolerance, requirement high positive end expiratory pressure, which could be resolved with facemask will applied as per facial contour patient. a transparent hood size measured head size. Both groups have standard protocol for titration NIV.Patients aged more than 18 years old diagnosed...
Acute kidney injury (AKI) is a serious medical condition that can have many causes, including rhabdomyolysis. Rhabdomyolysis the breakdown of muscle tissue lead to release fiber contents into bloodstream. This cause damage kidneys, leading AKI. In this case, young bodybuilder was diagnosed with rhabdomyolysis induced by AKI after consuming Ibuprofen for casual fever. The etiology in complex, multiple factors contributing development condition. These include trauma, dehydration, infection,...
Background: Critical illness-associated cerebral microbleeds and leukoencephalopathy connected to coronavirus disease 2019 (COVID-19) infection are emerging areas of concern in current medical literature. Methods: We reviewed cases patients with COVID-19-associated neurological manifestations study the prevalence outcome such conditions. Case Series Findings: Our review yielded seven distinct patients. Six exhibited microbleeds, primarily localized juxtacortical white matter corpus callosum....
Phlegmonous Gastritis (PG) is a rare and swiftly progressing disease that often fatal. It typically involves severe invasion of the gastric wall by bacteria. Due to its vague symptoms, diagnosis delayed. When suspicious, CT abdomen endoscopy will be helpful for early diagnosis. We describe case 45-year-old patient admitted with gastroenteritis symptoms rapidly progressed septic shock; showed features PG, which were further confirmed endoscopy. He underwent life-saving open salvage total...
The use of steroids and other immune modulatory therapies in the treatment severe COVID-19 pneumonia predisposes patients to reemergence opportunistic infections. Cytomegalovirus (CMV) reactivation can be one them. A 55-year-old gentleman with hypoxic respiratory failure who was ventilated received but no immunomodulatory drugs; had altered sensorium multiple episodes seizures later course his illness. Brain MRI showed leptomeningeal enhancement encephalopathy changes, electroencephalography...