Mostafa Najim

ORCID: 0000-0003-1848-2346
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About
Contact & Profiles
Research Areas
  • Diabetes Treatment and Management
  • COVID-19 Clinical Research Studies
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Venous Thromboembolism Diagnosis and Management
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Colorectal Cancer Screening and Detection
  • Metabolism, Diabetes, and Cancer
  • Tracheal and airway disorders
  • Global Cancer Incidence and Screening
  • Platelet Disorders and Treatments
  • Liver Disease Diagnosis and Treatment
  • Potassium and Related Disorders
  • Cardiac Arrhythmias and Treatments
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Thyroid and Parathyroid Surgery
  • Long-Term Effects of COVID-19
  • Systemic Lupus Erythematosus Research
  • Ion channel regulation and function
  • Cystic Fibrosis Research Advances
  • COVID-19 and healthcare impacts
  • Liver Disease and Transplantation
  • Cardiac Imaging and Diagnostics
  • Clinical practice guidelines implementation
  • Atrial Fibrillation Management and Outcomes

Unity Health System
2022-2025

Unity Hospital
2022-2025

Hamad Medical Corporation
2019-2024

Rochester General Hospital
2024

Development Fund
2022

Hamad General Hospital
2020-2021

Background: Hepatocellular carcinoma (HCC) remains one of the leading causes cancer-related fatalities despite early diagnosis and treatment progress, creating a significant public health issue in United States. This investigation utilized death certificate data from Centers for Disease Control Prevention Wide-ranging Online Data Epidemiologic Research (CDC WONDER) database to investigate HCC mortality patterns locations 1999 2020. The objective was analyze trends across different population...

10.14740/gr1743 article EN Gastroenterology Research 2024-06-01

ABSTRACT Background & Aims Alcoholic hepatitis (AH) is a severe manifestation of alcoholic liver disease with high morbidity and mortality. This study used the 2016–2020 National Readmission Database to investigate how obesity influences AH outcomes. Methods Adult hospitalizations were categorized as those without obesity, Class 1 (BMI 30–34.9), 2 35–39.9), or 3 ≥ 40). We compared mortality, complications, resource utilization across these groups using regression models. Results Among 82...

10.1002/jgh3.70166 article EN cc-by JGH Open 2025-04-01

Abstract Coronavirus disease 2019 (COVID-19) increases the risk of coagulopathy. Although presence antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism COVID-19-induced coagulopathy, its clinical significance remains uncertain. Therefore, this study aimed to evaluate prevalence and aPLs among critically ill patients with COVID-19. This prospective observational included 60 COVID-19 admitted intensive care units (ICU). The outcomes aPLs, primary composite outcome...

10.1007/s00296-021-04875-7 article EN cc-by Rheumatology International 2021-05-05

Introduction Immune thrombocytopenia (ITP) management with co-existing acute coronary syndrome (ACS) remains challenging as it requires a clinically relevant balance between the risk and outcomes of thrombosis bleeding. However, literature evaluating treatment approaches in this high-risk population is scarce. Methods Results In review, we aimed to summarize available on safety ITP first- second-line therapies provide practical guide ACS. We recommend holding antithrombotic therapy,...

10.3389/fmed.2024.1348941 article EN cc-by Frontiers in Medicine 2024-04-11

Enterococcus species is one of the leading causes community and healthcare-associated infections resulting in significant morbidity mortality. In this study, we aim to evaluate epidemiology, microbiological clinical characteristics Blood Stream Infections (BSIs) over 10 years period a national secondary care setting.A retrospective cohort study was conducted on verified cases enterococcal BSIs adults from January 2009-December 2018 specialized hospitals at Hamad Medical Corporation, Qatar....

10.1016/j.amsu.2022.104258 article EN Annals of Medicine and Surgery 2022-08-01

Background Acute coronary syndrome (ACS) remains a risk factor for heart failure (HF). Therefore, we aimed to assess the cardioprotective role of sodium–glucose cotransporter-2 (SGLT2) inhibitors post-ACS in patients with acute HF (AHF) and diabetes. Methods We conducted retrospective observational cohort study employing propensity score matching. This involved diabetes admitted ACS complicated by AHF, defined as either new clinical requiring diuretics during index admission or having an...

10.3389/fcvm.2024.1383669 article EN cc-by Frontiers in Cardiovascular Medicine 2024-05-20

Surgical clip migration is a rare complication that can happen many years following successful cholecystectomy. It has similar clinical presentation as choledocholithiasis. The diagnosis usually made using imaging modalities such ultrasounds, computed tomography (CT) scans, or magnetic resonance cholangiopancreatography (MRCP). If left untreated, complications acute cholangitis, pancreatitis, embolism, duodenal ulcer, and obstructive jaundice develop. Endoscopic retrograde (ERCP) the...

10.21037/acr-24-77 article EN AME Case Reports 2024-10-21

This case report presents the management of a 53-year-old female with complex psychiatric history who ingested multiple medications, resulting in severe cardiovascular compromise and subsequent respiratory failure. The patient’s ingestion included clonidine, fluoxetine, gabapentin, quetiapine bupropion. Initial treatment involved supportive measures, including fluid resuscitation, bicarbonate infusion correction electrolyte imbalances. Despite these interventions, patient remained...

10.12890/2023_004025 article EN cc-by-nc-nd European Journal of Case Reports in Internal Medicine 2023-10-26

Purpose: The aim of this study was to evaluate the rate internal medicine residents' and faculties' (specialists consultants) compliance colorectal cancer screening in Hamad Medical Corporation (Doha, Qatar) identify barriers as well facilitators that will assist drawing up changes would enhance physician-related screening. Methods: A cross-sectional web-based survey distributed among physicians at three component hospitals (HMC); focusing on knowledge practice screening, its facilitators....

10.2147/amep.s268315 article EN cc-by-nc Advances in Medical Education and Practice 2020-11-01

Symptomatic hypocalcemia is frequently encountered in the Emergency Department, necessitating admission. It has a variety of underlying etiologies, with hypoparathyroidism and vitamin D deficiency being most common. However, rarer etiologies such as pseudohypoparathyroidism, was present current case, should not be overlooked. Reported here case young female patient presenting generalized tonic clonic seizures. Electrocardiography revealed prolonged QT interval which pointed towards metabolic...

10.5582/irdr.2020.03014 article EN Intractable & Rare Diseases Research 2020-06-01

Introduction: Colchicine acts upstream in the cytokines cascade by inhibiting nod-like receptor protein 3 (NLRP3) inflammasome while interleukin 6 (IL-6) antagonists, such as tocilizumab, block end result of cascade. Hence, adding colchicine to tocilizumab with aim blocking early and products cascade, might reduce risk developing cytokine storm. Methods analysis: We conduct an open-label randomized controlled trial evaluate efficacy safety among patients severe COVID-19 pneumonia rate...

10.1097/md.0000000000030843 article EN cc-by-nc Medicine 2022-09-30

Acute pulmonary edema is one of the frequent causes dyspnea encountered in everyday practice. It broadly attributed to be either cardiogenic or noncardiogenic. usually treated with diuretics addition other medications depending on underlying pathology. Here, we report a case female patient who presented shortness breath after developing seizure. Further investigations excluded etiology and showed critically low phenytoin level. improved within 48 h supportive care without giving favoring...

10.1155/2019/6867042 article EN cc-by Case Reports in Neurological Medicine 2019-10-09

Background: Computed tomography (CT) features of cystic fibrosis (CF) lung disease can be objectively quantified using current CT scoring systems to assess the extent and severity disease. The aims this study were calculate Santamaria scores in adult patients with CF predominant CFTR I1234V genotype, determine its reliability, correlate these parameters function, microbial colonization, compliance treatment, exacerbations. Methodology: This retrospective observational was conducted on who...

10.5339/qmj.2020.4 article EN cc-by Qatar medical journal 2020-03-02

Abstract Sustained low-efficiency dialysis (SLED) is usually performed over 6–12 h among hemodynamically unstable patients. Conduction of 4-h SLED may spare time and manpower during hospitalization. Therefore, we conducted a retrospective observational study to explore the appropriateness clinical outcomes critically ill patients admitted our center from 1/06/2016 1/06/2020. Renal parameters including blood urea nitrogen, serum creatinine, sodium, phosphorus, potassium, bicarbonate were...

10.1515/med-2023-0868 article EN cc-by Open Medicine 2023-01-01

Organizing pneumonia (OP) is a form of interstitial lung disease that develops in response to acute injury. SARS-CoV-2 causes wide range and extrapulmonary disease, but there are few data suggesting an association between COVID-19 OP. We describe patient with who developed severe progressive OP significant morbidity.COVID-19 one the secondary organizing (OP).Early initiation steroids associated improvement symptoms prognosis.A prolonged course may be needed COVID-induced

10.12890/2023_003787 article EN cc-by-nc-nd European Journal of Case Reports in Internal Medicine 2023-02-16
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