- Pain Management and Placebo Effect
- Complementary and Alternative Medicine Studies
- Empathy and Medical Education
- Psychotherapy Techniques and Applications
- Menstrual Health and Disorders
- Counseling, Therapy, and Family Dynamics
- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Patient-Provider Communication in Healthcare
- Psychiatric care and mental health services
- Mental Health and Psychiatry
- Optimism, Hope, and Well-being
- Acupuncture Treatment Research Studies
- Pain Mechanisms and Treatments
- Religion, Spirituality, and Psychology
University of Basel
2017-2025
Abstract Research on open-label placebos questions whether deception is a necessary characteristic of placebo effects. Yet, comparisons between and deceptive (DPs) are lacking. We therefore assessed effects DPs in comparison with no treatment (NT) standardized experimental heat pain paradigm randomized controlled trial healthy participants. Participants (N = 160) were randomly assigned to NT, without rationale (OPR-), (OPR + ), DP. conducted baseline posttreatment measurements threshold...
Objective To investigate the efficacy and safety of open-label placebos (OLP) in premenstrual syndrome (PMS). Design Randomised controlled trial. Setting Switzerland, 2018–2020. Participants 150 women (18–45 years age) with PMS or dysphoric disorder. Intervention Random assignment (1:1:1) to treatment as usual (TAU), OLP without rationale (OLP–), (OLP+). consisted two placebo pills per day for 6 weeks. Main outcome measures Primary outcomes were symptom intensity interference between groups...
Abstract Objective Highly distressed cancer patients often do not use psycho‐oncological services (POS). Research on predictors of POS uptake has mainly focused patient‐related variables and less communication variables, so we examined the link between patient‐oncologist (ie, talking about psychosocial distress, providing detailed information, recommending POS) uptake. Methods We conducted a prospective, observational study in an Oncology Outpatient Clinic Switzerland. Predictors patient's...
Introduction Recent evidence suggests that for certain clinical conditions, placebos can improve outcomes even without deception. These so-called open-label (OLPs) bear the advantage of a significant lower risk adverse events and comply with ethical principles. Although premenstrual syndrome (PMS) seems to be considerably susceptible placebo effects, no study has examined open-OLP responses on PMS. Methods analysis To test efficacy OLPs in women suffering from PMS, randomised controlled...
Introduction Chronic non-cancer pain presents a global health problem, with significant increase in opioid prescriptions over recent decades. However, therapy poses risks of adverse events, overdose and non-medical use. As result, many patients seek to discontinue or reduce their intake. Strategies for tapering often lack efficacy, prompting the investigation novel approaches like open-label placebo (OLP), that is, administration full disclosure it is placebo. OLP has shown efficacy chronic...
The evidence-based practice movement clearly defines the relevant components of a good treatment. In present article, we elaborate on how active involvement patients within psychotherapy can and should be increased in order to respect ethical considerations. Our arguments complement requirements practice, are independent actual psychotherapeutic treatment approach being used. Theoretical analysis. patient autonomy, needs transparent honest when it comes disclosing factors for promoting...
Objectives To analyse participants’ concepts about the open-label placebo (OLP) effect; to explore their views discussion points that are applied in conventional OLP trials and examine experiences of taking part an trial. Design A qualitative study using thematic analysis semistructured interviews were nested within a randomised controlled trial investigating experimental analgesia (registered at ClinicalTrials.gov: NCT02578420 ). Participants 30 healthy adults who took Results mostly...