A5031359909- Advanced biosensing and bioanalysis techniques
- Per- and polyfluoroalkyl substances research
- Luminescence and Fluorescent Materials
- Nanoplatforms for cancer theranostics
- Marine Bivalve and Aquaculture Studies
- Cellular Mechanics and Interactions
- Marine Biology and Ecology Research
- Photosynthetic Processes and Mechanisms
- Advanced Photocatalysis Techniques
- Toxic Organic Pollutants Impact
- Biosensors and Analytical Detection
- DNA and Nucleic Acid Chemistry
- Molecular Sensors and Ion Detection
- Microfluidic and Bio-sensing Technologies
- Semiconductor Quantum Structures and Devices
- Corrosion Behavior and Inhibition
- Marine Biology and Environmental Chemistry
- Plant tissue culture and regeneration
- Effects and risks of endocrine disrupting chemicals
- Advanced Semiconductor Detectors and Materials
- 3D Printing in Biomedical Research
- Aquatic Invertebrate Ecology and Behavior
- Microfluidic and Capillary Electrophoresis Applications
- Organic Light-Emitting Diodes Research
- Genomics and Phylogenetic Studies
Northeast Normal University
2022-2025
Shenzhen University
2022-2025
Institute of Oceanology
2015-2024
Chinese Academy of Sciences
2015-2024
Fuzhou Maternity and Child Health Care Hospital
2024
Fujian Medical University
2024
Guilin Medical University
2023-2024
University of Chinese Academy of Sciences
2021-2024
Laoshan Laboratory
2023
Qingdao National Laboratory for Marine Science and Technology
2018-2023
Driven by increasingly stringent restrictions on long-chain per- and polyfluoroalkyl substances (PFASs), novel fluorinated compounds have emerged the market. Here we report occurrences of several perfluoroalkyl ether carboxylic sulfonic acids (PFECAs PFESAs), including hexafluoropropylene oxide dimer trimer (HFPO-DA HFPO-TA), ammonium 4,8-dioxa-3 H-perfluorononanoate (ADONA), chlorinated polyfluorinated acid (6:2 Cl-PFESA), its hydrogen-substituted analogue H-PFESA) in surface waters from...
Here, we report on the occurrence of a novel perfluoroalkyl ether carboxylic acid, ammonium perfluoro-2-[(propoxy)propoxy]-1-propanoate (HFPO-TA), in surface water and common carp (Cyprinus carpio) collected from Xiaoqing River residents residing near fluoropolymer production plant Huantai County, China. Compared with levels upstream River, HFPO-TA concentrations (5200-68500 ng/L) were approximately 120-1600-times higher downstream after receiving effluent tributary. The riverine discharge...
Abstract Tuberculosis, a fatal infectious disease caused by Mycobacterium tuberculosis ( M.tb ), is difficult to treat with antibiotics due drug resistance and short half‐life. Phototherapy represents promising alternative in combating . Exploring an intelligent material allowing effective treatment definitely appealing, yet significantly challenging task. Herein, all‐in‐one biomimetic therapeutic nanoparticle featured aggregation‐induced second near‐infrared emission, granuloma‐targeting,...
Marine optical instruments are bearing serious biofouling problem, which affects the accuracy of data collected. To solve problem marine instruments, a novel instance slippery lubricant-infused porous surface (SLIPS) with high underwater-transparency was designed over glass substrate via infusing lubricant into its microstructure fabricated hydrothermal method. The advantage SLIPS as antibiofouling strategy to proven by comparing underwater and performances three kinds samples (hydrophilic...
As an alternative to perfluorooctanoic acid (PFOA), hexafluoropropylene oxide trimer (HFPO-TA) has been increasingly used for fluoropolymer manufacture in recent years. Its growing detection environmental matrices and wildlife raises considerable concern about its potential health risks. Here we investigated the effects of HFPO-TA on mouse liver following 28 days exposure 0.02, 0.1, or 0.5 mg/kg/d via oral gavage. Results showed that concentrations increased 1.14, 4.48, 30.8 μg/mL serum...
Novel visible-light-sensitive Bi<sub>2</sub>WO<sub>6</sub>/BiVO<sub>4</sub> nest-like hierarchical microspheres were controllably synthesized for photocatalytic antifouling.
The compound 6:2 chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA), an alternative to perfluorooctanesulfonate (PFOS) in the metal-plating industry, has been widely detected various environmental matrices. However, its hepatotoxicity yet be clarified. Here, male mice were exposed 0.04, 0.2, or 1 mg/kg/day of Cl-PFESA for 56 days. Results demonstrated that relative liver weight increased significantly 0.2 and groups, whereas lipid accumulation all groups. Serum enzyme activities...
A novel fungal gene encoding the Rhizomucor miehei l-asparaginase (RmAsnase) was cloned and expressed in Escherichia coli. Its deduced amino acid sequence shared only 57% identity with sequences of other reported l-asparaginases. The purified homodimer had a molecular mass 133.7 kDa, high specific activity 1,985 U/mg, very low glutaminase activity. RmAsnase optimally active at pH 7.0 45°C stable this temperature for 30 min. final level acrylamide biscuits bread decreased by about 81.6%...
Emerging epidemiological evidence has linked per- and polyfluoroalkyl substances (PFAS) exposure could be to the disturbance of gestational glucolipid metabolism, but toxicological mechanism is unclear, especially when at a low level. This study examined metabolic changes in pregnant rats treated with relatively dose perfluorooctanesulfonic acid (PFOS) through oral gavage during pregnancy [gestational day (GD): 1–18]. We explored molecular mechanisms underlying perturbation. Oral glucose...
A combination of spectroscopy and DFT calculations has been used to define the geometric electronic structure nitrite bound type 2 (T2) copper site at high low pH in reductase from Rhodobacter sphaeroides. At there is no electron transfer reduced 1 (T1) T2 copper, while protonation triggers T1 → generation NO. The calculated reaction coordinate for N−O bond cleavage reduction by suggests that process best described as proton triggering transfer. Bidentate binding play a major role activating...
Mussels (Bivalve: Mytilidae) have adapted to various habitats, from fresh water the deep sea. To understand their adaptive characteristics in different particularly bathymodiolin mussels deep-sea chemosynthetic ecosystems, we conducted a comparative transcriptomic analysis between and shallow-water relatives. A number of gene families related stress responses were shared across all mussels, without specific or significantly expanded species, indicating that are capable adapting diverse harsh...
As novel alternatives to perfluorooctanoic acid (PFOA), perfluoropolyether carboxylic acids (multiether PFECAs, CF3(OCF2)nCOO–, n = 2–4) have been detected in various environmental matrices; however, public information regarding their toxicities remains unavailable. To compare the hepatotoxicity of multiether PFECAs (e.g., PFO2HxA, PFO3OA, and PFO4DA) with PFOA, male mice were exposed 0.4, 2, or 10 mg/kg/d each chemical for 28 d, respectively. Results demonstrated that PFO2HxA PFO3OA...