A5020209235- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Vascular Malformations Diagnosis and Treatment
- Retinal Imaging and Analysis
- Retinal Development and Disorders
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Ophthalmology and Visual Impairment Studies
- Acupuncture Treatment Research Studies
- Orthopedic Surgery and Rehabilitation
- Viral gastroenteritis research and epidemiology
- Corneal Surgery and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Ocular Disorders and Treatments
- Optical Coherence Tomography Applications
- Cell Adhesion Molecules Research
- Ocular Infections and Treatments
- Pain Mechanisms and Treatments
- Viral Infections and Immunology Research
- Systemic Lupus Erythematosus Research
- Ocular and Laser Science Research
- Corneal surgery and disorders
- Digital Radiography and Breast Imaging
Beijing Tongren Hospital
2016-2025
Capital Medical University
2016-2025
Beijing Hospital of Traditional Chinese Medicine
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2025
Wangjing Hospital of China Academy of Chinese Medical Sciences
2022-2025
Gansu Provincial Center for Disease Control and Prevention
2025
Dalian Medical University
2019-2024
Shanghai Ninth People's Hospital
2024
Shanghai Jiao Tong University
2024
Hunan Cancer Hospital
2022-2024
<h3>Objective</h3>To determine the prevalence, characteristics, and risk factors for myopic retinopathy in a rural population Northern China.<h3>Methods</h3>The Handan Eye Study is population-based study of eye disease Chinese individuals 30 years or older. Eligible residents underwent detailed ophthalmic examination including standardized visual acuity tests retinal photography after pupil dilation. Myopic was defined to include signs staphyloma, lacquer cracks, Fuchs spot, chorioretinal...
To determine the prevalence and association of epiretinal membranes (ERMs), as assessed by retinal photography optical coherence tomography (OCT), in a Chinese population.The Handan Eye Study is population-based study eye disease rural aged 30+ years. Eligible residents underwent detailed ophthalmic examination including Stratus OCT. ERMs were defined combination photographs OCT classified cellophane macular reflex (CMR) or preretinal fibrosis (PMF) based on characteristics.Of 6830 persons...
The involvement of local and systemic oxidative stress in intraocular pressure (IOP) elevation optic nerve damage has been hypothesized the pathogenesis glaucoma. In this study, we aim to evaluate antioxidant effects curcumin BV-2 microglia assess its neuroprotective a chronic high IOP rat model.BV-2 cell line was used an vitro study Wistar rats were vivo study. Cultured cells pretreated with 10, 1, or 0.1 μM for 1 h, sustained induced by subjecting 200 hydrogen peroxide (H2O2) 24 h. MTT...
Norovirus (NoV) causes epidemic acute gastroenteritis in humans, whereby histo-blood group antigens (HBGAs) play an important role host susceptibility. Each of the two major genogroups (GI and GII) human NoVs recognizes a unique set HBGAs through distinct binding interface that is conserved within genogroup, indicating evolutionary path for each genogroup. Here, we characterize Lewis (Lea) antigen strain (OIF virus) GII.21 genotype does not share GII interface, revealing new evolution...
Choroidal detachment (CD) following primary rhegmatogenous retinal (RRD) is a special type of RRD. The purpose this study to investigate the potential risk factors RRD with CD in Chinese population.All 201 consecutive patients and 210 without were enrolled case-control retrospective study. clinical data from these cases reviewed here. Patients undergone scleral buckling or encircling both, pars plana vitrectomy both according patients' condition. incidence population was measured, for...
In Brief Purpose: To investigate the concentrations and pharmacokinetics of ketorolac in rabbits by three different routes administrations: a single intracameral, intravitreal, suprachoroidal injection. Methods: Fifty-four New Zealand white received (250 μg/0.05 mL) one eye intracameral injection (group A, n = 18), intravitreal B, C, 18). Drug vitreous, retina–choroid (RC), plasma were determined methods high-performance liquid chromatography at 0.5, 1, 2, 4, 8, 24 hours after The opposite...
Introduction: The aim of this study was to evaluate the clinical characteristics and surgical outcomes epiretinal membrane foveoschisis (ERM-FS) with different morphological types. Methods: This retrospective observational reviewed 44 consecutive ERM-FS patients who underwent ERM surgery. According optical coherence tomography images, classified into three groups: group A, FS crossed fovea foveola elevated; B, located at foveal edges a near-normal central point thickness; C, undermined...
Purpose: To evaluate the effect of internal limiting membrane peeling and air tamponade for idiopathic macular hole, explore reasons interventions persistent holes. Methods: One hundred thirty-five eyes with Stage III IV hole that underwent 23-gauge vitrectomy, peeling, were reviewed. Eyes holes a second surgery. Outcome-related factors treating discussed. Results: The initial closure (Type I) rate was 89.63% (121/135). surgery all obtained final I). Diameter significantly smaller ( P <...
Diabetic cardiomyopathy (DCM) is one of the common cardiovascular complications in patients with diabetes. Accumulating evidence has demonstrated that DCM thoroughly related to mitochondrial energy impairment and increases generation reactive oxygen species (ROS). Therefore, an ongoing study developing strategies protect cardiac mitochondria from diabetic complications, especially hyperglycemia. Phosphocreatine (PCr) plays a major metabolic role muscular cells including intracellular...
Purpose: This work aimed to study the effect of posterior scleral reinforcement (PSR) on choroidal thickness (CT) and blood flow. Methods: included 25 eyes 24 patients with high myopia ( ≤ -6.0 dioptres or axial length ≥ 26.0 mm) who underwent PSR surgery. All completed 1-month follow-up visit. Myopic macular degeneration (MMD) was graded according International Meta-Analysis for Pathologic Myopia (META-PM) classification based color fundus photographs. Swept-source optical coherence...
To report the characteristics and surgical outcomes of full-thickness macular holes (MHs) accidently caused by laser devices analyze visual predictors. Thirty-three eyes that underwent vitrectomy for laser-induced MHs were included. Full ophthalmic examinations optical coherence tomography used assessment at baseline follow-ups. Preoperative 6 months postoperative features analyzed, respectively, as potential predictors final acuity (VA). Eleven injured a neodymium-doped yttrium aluminum...
Background: Renal tubule hypoxia injury plays a pivotal role in the development of renal fibrosis diabetic kidney disease (DKD). The Qi-Huang-Yi-Shen formula (QHYS) is traditional Chinese medicine compound used for treating DKD. Nevertheless, underlying mechanism remains unclear. Therefore, this study aimed to investigate whether QHYS could inhibit tubular epithelial-mesenchymal transition (EMT) through hypoxia-inducible factor-1 alpha (HIF-1α) /snail pathway, thereby conferring protection....
Introduction: The outcomes and prognosis of pars plana vitrectomy (PPV) for high myopia epiretinal membranes (HM-ERM) patients with retinoschisis remains unclear. To analyze the impact on recovery macular configuration visual acuity following ERM removal in eyes HM to explore prognostic factors. Methods: A retrospective study 73 consecutive HM-ERM who underwent PPV peeling. According optical coherence tomography images, were classified into 4 groups: group without retinoschisis, B outer C...
The pathogenesis of age-related macular degeneration (AMD) is complex. It has been shown that vitreomacular traction (VMT) plays a role in the AMD. We speculate continuous stretch induced by VMT might impair function retinal pigment epithelium (RPE) cells and it also be involved progression Cultured ARPE-19 were subjected to cyclic on Flexcell Strain system at level 25% increment surface area for 8 h, 14 20 24 h. In another group, was withdrawn h cell cultured 6 Then, we observed changes...
Vitreomacular adhesion (VMA) has been reported to associated with age-related macular degeneration (AMD). Understanding the mechanisms underlying cyclic stretch induced in retinal pigment epithelial cells (RPE) may be important for treatment of VMA-related AMD.Cyclic (1HZ, 20% elongation) was applied cultured ARPE-19 15 min, 2 h, 6 12 24 h by flexcell FX-5000 Tension system. Total reactive oxygen species (ROS) were detected using DCFH-DA. Mitochondrial superoxide MitoSOX Red mitochondrial...