A5037298244- vaccines and immunoinformatics approaches
- Hepatitis C virus research
- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
- Liver Disease Diagnosis and Treatment
- Hepatitis Viruses Studies and Epidemiology
- HIV Research and Treatment
- Mosquito-borne diseases and control
- Systemic Lupus Erythematosus Research
- Immune Cell Function and Interaction
- Viral gastroenteritis research and epidemiology
- COVID-19 diagnosis using AI
- Monoclonal and Polyclonal Antibodies Research
- Organometallic Compounds Synthesis and Characterization
- Moringa oleifera research and applications
- Global Security and Public Health
- Synthesis and biological activity
- COVID-19 impact on air quality
- Healthcare Systems and Reforms
- Migration, Health and Trauma
- Machine Learning in Bioinformatics
- HIV/AIDS Impact and Responses
- HIV, Drug Use, Sexual Risk
University of Bahrain
2013-2023
Hepatitis B infection is one of the world's major infectious diseases with about 350 million chronic carriers. Because no data published on prevalence and risk factors this important disease in Bahrain, article evaluates available from 2000 to 2010 estimate evaluate factors. Epidemiologic HBV cases were collected hospitals health centers Bahrain statistically analyzed. Over indicated decade, 877,892 individuals screened for 5055 positive reported Bahrain. The during that period was 0.58%....
Proactive prediction of the epidemiologic dynamics viral diseases and outbreaks type COVID-19 has remained a difficult pursuit for scientists, public health researchers, policymakers. It is unclear whether RT-PCR Cycle Threshold (Ct) values - or any other virus as indicator load, could represent possible predictor underlying changes on population level. The study objective thus to investigate population-wide in SARS-CoV-2 Ct over time are associated with daily fraction positive tests. In...
The study on Erucin (ER) has gained interest of nutraceutical and pharmaceutical industries because its anti-cancer properties. is an isothiocyanate obtained from the seeds Eruca sativa which possess certain drawbacks such as poor aqueous solubility bioavailability. Therefore, present aimed at developing ER-cubosomes (CUB) by solvent evaporation technique followed applying Central Composite Design to optimize ER loaded cubosomes. For this purpose, independent variables selected were...
HIV/AIDS is one of the major health problems worldwide. Despite low prevalence HIV in Bahrain, educational and awareness programs remain highly important controlling preventing spread disease. This study aimed to assess public's knowledge, risk perceptions, attitudes towards Bahrain.A self-administered questionnaire-based survey was administered completed by 1,038 Bahraini adults.Although average general among participants good (63%), some misconceptions erroneous beliefs were common,...
The incidence of enteric viruses in treated wastewater and their potential release into the environment or use for agriculture are very critical matters public health. In our study, PCR (polymerase chain reaction) analysis was performed on 59 samples influents effluents collected from Tubli treatment plant (Water Pollution Control Center (WPCC)) Bay, where were discharged, Kingdom Bahrain during two sampling periods. Four clinically essential waterborne examined: enterovirus (EV), hepatitis...
BACKGROUND: To combat the global health issue caused by SARS-CoV2, scientists are attempting various therapeutic approaches towards drug discovery including computational biology and drug-repurposing. Recent studies have highlighted conserved nature of RNA-dependent RNA polymerase (RdRp) coronaviruses affecting human, bat animals. In this study attempts been made to identify potential inhibitors RdRp utilizing molecular docking MD simulation studies.METHODS: Systematic structure-based...
Approximately 170 million people are infected with Hepatitis C virus (HCV) worldwide, making it one of the world's major infectious diseases. There no published population based studies about prevalence HCV genotypes in Bahrain.Therefore, aim present study was to investigate and distribution subtypes among a large sample patients chronic infection Bahrain.Serum samples were collected from 202 positive patients; them 128 had viral load (> 500 IU/mL) suitable for type-specific genotyping...
Introduction: Proactive prediction of the epidemiologic dynamics viral diseases and outbreaks likes COVID-19 has remained a difficult pursuit for scientists, public health researchers, policymakers. It is unclear whether RT-PCR Cycle Threshold (Ct) values (or any other virus) as indicator load, could represent possible predictor underlying epidemiological changes on population level. Objectives: To investigate population-wide in SARS-CoV-2 Ct over time are associated with daily fraction...
Quercetin is one of the most powerful bioactive dietary flavonoids. The in vivo biological study quercetin extremely difficult due to its very low solubility. However, diorganotin complexes are more useful when contrasted with increased In present study, quercetin, substituted biguanide synthesized form Schiff base and di-alkyl/aryl tin (IV) were obtained by condensing respective dichloride. Advanced analytical techniques used for structural elucidation. results screening against...
Zika virus (ZIKV) is a mosquito-borne flavivirus distributed all over Africa, South America and Asia. The infection with the may cause acute febrile sickness that clinically resembles dengue fever, yet there no vaccine, satisfactory treatment, means of evaluating risk disease or prognosis in infected people. In present study, efficacy host's immune response reducing infectious diseases was taken into account to carry out immuno-informatics driven epitope screening strategy vaccine candidates...
Background: Approximately 400 million people are infected with Hepatitis B virus (HBV) around the world, which makes it one of world's major infectious diseases. The prevalence HBV genotypes and predictive factors for risk poorly known in Kingdom Bahrain. Objectives: aim present study was to investigate genotypes, its correlation demographic factor sand impacts on hepatic biomarkers. Materials Methods: Venous blood samples were collected from 82 positive patients (48 males, 34 females)....
Streptococcus pneumoniae is one of the major precarious pathogens accountable for over 1.2 million fatalities annually. The key drivers pneumococcal vaccine development involve high morbidity and mortality in cases, especially very young children elderly. In this study, immunoinformatics was integrated with subtractive proteomics to find antigenic proteins designing a multi-epitope against S. pneumoniae. As prospective targets, developed pipeline identified two proteins, i.e.,...
BACKGROUND: Recurrent outbreaks of respiratory viruses like SARS-CoV (severe acute syndrome-coronavirus, 2002), MERS (Middle East syndrome, 2012) including the ongoing SARS-CoV-2 (2019) pandemic warrants for a single-broad-spectrum vaccine against these viruses.METHODS: In present study, phylogenetic analysis followed by in-silico identification candidates SARS, and was performed exploiting T-cell B-cell mapping to ascertain best possible epitopes effector humoral- cell-mediated immune...
Rapid economic and industrial developments population growth in Bahrain are associated with increases energy demand greenhouse gas emissions. An Environmental Impact Assessment (EIA) process has been adopted the country to address environmental aspects within intensive projects such as oil petrochemical industries. The quality of EIA reports respect conservation emissions was investigated this study. results obtained showed that received more attention than conservation. reflected a good...
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