Лариса Анатольевна Тарарина

ORCID: 0000-0001-8006-698X
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Research Areas
  • Nanoplatforms for cancer theranostics
  • Photodynamic Therapy Research Studies
  • Nanoparticle-Based Drug Delivery
  • Porphyrin and Phthalocyanine Chemistry
  • Phytochemistry and Biological Activities
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Abdominal Trauma and Injuries
  • Multiple Myeloma Research and Treatments
  • Inflammatory mediators and NSAID effects
  • Sensory Analysis and Statistical Methods
  • Lipid Membrane Structure and Behavior
  • Occupational and environmental lung diseases
  • Toxin Mechanisms and Immunotoxins
  • Helicobacter pylori-related gastroenterology studies
  • Analytical Methods in Pharmaceuticals
  • Neonatal Respiratory Health Research
  • SARS-CoV-2 and COVID-19 Research
  • Rheumatoid Arthritis Research and Therapies
  • Eosinophilic Esophagitis
  • Medicinal plant effects and applications
  • Biochemical Analysis and Sensing Techniques
  • Pleural and Pulmonary Diseases
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • Natural product bioactivities and synthesis

Moscow State University of Medicine and Dentistry
2019-2024

Ministry of Health of the Russian Federation
2019-2024

Introduction: For people with allergies, it is not always possible to prevent allergens admission the body. this reason, essential create a long-acting drug that can an allergic reaction. The very promising option transdermal therapeutic system (TTS), H1 blockers. aim of study: To technology for production desloratadine-based TTS, suitable routine use prolonged releasing. Materials and Methods: Polyvinylpyrrolidone K30 (PVP) was used as main matrix polymer Kruofilm membrane adhesive layer....

10.18413/rrpharmacology.10.487 article EN cc-by Research Results in Pharmacology 2024-06-28

This review examines the consequences of excessive consumption sweet products on human health and explores potential sugar substitutes intensive sweeteners, including proteins, as their healthier alternatives. Analyzing statistical data prevalence diabetes obesity, study highlights risks associated with high intake. An extensive properties various sweeteners has been conducted, focusing glycemic index sweetness level. Special attention is given to such monellin brazzein, structure,...

10.33667/2078-5631-2024-16-58-64 article EN Medical alphabet 2024-09-05

Introduction. The inefficiency of proton pump inhibitors (PPIs) in patients with symptoms gastroesophageal reflux disease (GERD) may be caused by functional esophageal diseases, which should diagnosed using pH-impedance monitoring. Aim. To evaluate the clinical efficacy therapies after phenotyping based on 24-h Materials and methods. A total 61 GERD were observed a prospective study. categorized into 3 phenotypes Lyon Consensus 2.0 Rome criteria IV: nonerosive (NERD), hypersensitive...

10.21518/ms2024-406 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2024-10-16

Objective. To investigate the possibility of pharmacological correction acute lung injury aspiration genesis with a liposomal form dexamethasone in experiment. Materials and methods. For experiment, simple liposomes were prepared from phosphatidylcholine cholesterol an average size 320±50 nm concentration 2.98±0.02 mg/ml. The study used outbred white rats, divided into four groups 16 animals. 1st group Control (without experimental therapy), 2nd - Experiment 1, where solution was injected...

10.21626/vestnik/2021-3/05 article EN Человек и его здоровье 2021-11-01

Introduction: Photodynamic therapy is a promising method of tumors treatment using photosensitizers and light certain wavelength. PS modification improves enhances the phototoxic effect with decreased dark cytotoxicity. Materials Methods: We compared photosensitizing polyelectrolyte microcapsules chlorin E6 (ClE6) free ClE6 at equivalent concentrations on murine fibroblast culture L929 in vitro tests. Microcapsules were prepared layer by layer, sequentially depositing oppositely charged...

10.18413/rrpharmacology.9.10055 article EN cc-by Research Results in Pharmacology 2023-11-15

Introduction: The study of the pharmacokinetics glucocorticosteroids is often required to solve fundamental and applied tasks pharmacology. HPLC methods based on ultraviolet detection are attractive due their availability, but sensitivity low enough in vivo kinetics. In this study, we propose a method for determination dexamethasone biological objects, use with UV having sufficient determine drug media (blood periarticular tissues). Materials methods: Extraction from biosamples was carried...

10.18413/rrpharmacology.9.10045 article EN cc-by Research Results in Pharmacology 2023-09-30
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