A5027380772- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Radiomics and Machine Learning in Medical Imaging
- Neuroendocrine Tumor Research Advances
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal and Anal Carcinomas
- Genetic factors in colorectal cancer
- Lung Cancer Research Studies
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Pancreatitis Pathology and Treatment
- Biliary and Gastrointestinal Fistulas
- Colorectal Cancer Treatments and Studies
- Gastrointestinal disorders and treatments
- Helicobacter pylori-related gastroenterology studies
- Viral-associated cancers and disorders
- Metastasis and carcinoma case studies
- Cancer, Lipids, and Metabolism
- Wound Healing and Treatments
- Colorectal Cancer Screening and Detection
- Liver Disease and Transplantation
- Galectins and Cancer Biology
- Hernia repair and management
İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi
2022-2025
Sağlık Bilimleri Üniversitesi
2018-2025
Istanbul Metropolitan Municipality
2025
University of Health Sciences Antigua
2020-2023
İstanbul Eğitim ve Araştırma Hastanesi
2017-2021
Emory University
2010-2020
University of Health Sciences
2020
Education Training And Research
2009-2019
Orient-Institut Istanbul
2018
Samsung Medical Center
2015
The literature on the clinicopathologic characteristics of tumoral intraepithelial neoplasms (neoplastic polyps) gallbladder (GB) is fairly limited, due in part to variability definition and terminology. Most reported adenomas (pyloric gland type others) were microscopic thus regarded as clinically inconsequential, whereas papillary situ carcinomas have been largely considered a invasive adenocarcinoma under heading "papillary adenocarcinomas." In this study, 123 GB cases that well-defined...
GLUT-1 has been found to have an important role in the upregulation of various cellular pathways and implicated neoplastic transformation correlating with biological behavior malignancies. However, literature regarding significance expression pancreatic neoplasia limited controversial.Immunohistochemical was tested a variety including ductal adenocarcinomas (DAs), intraepithelial neoplasms (PanINs), intraductal papillary mucinous (IPMNs), serous cystadenomas.There progressive increase from...
There are virtually no data in the literature regarding incidence, patterns, and clinicopathologic characteristics of mucinous carcinomas (MCs) gallbladder (GB).To determine incidence differentiation invasive GB those that qualify as MC.Primary (n = 606) were reviewed for differentiation. Some degree mucin production was identified 40 cases (6.6%); however, only 15 (2.5%) qualified World Health Organization definition MC (stromal deposition constituting >50% tumor).The mean age 65 years,...
Background Different perspectives exist regarding the clinicopathologic characteristics, biology and management of gallbladder polyps. Size is often used as surrogate evidence polyp behavior size ≥1cm widely cholecystectomy indication. Most studies on this issue are based pathologic correlation polyps clinically selected for resection, whereas, data nature polypoid lesions from pathology perspective -regardless indication- highly limited. Methods In study, 4231 gallbladders -606 which had...
We describe a clinicopathologically distinct subtype of cholecystitis, the extensively calcific version which has been presented in clinical literature as "porcelain gallbladder (PG)." This we propose to refer hyalinizing cholecystitis (HC), is characterized by dense, paucicellular hyaline fibrosis transforming (GB) wall into relatively thin and uniform band. The process diffusely effaces most normal structures GB, some cases show calcifications. To determine clinicopathologic associations...
Purpose Lymphovascular invasion (LVI) and perineural (PNI) are associated with poor prognosis in gastric cancers. In this work, we aimed to investigate the potential role of computed tomography (CT) texture analysis predicting LVI PNI patients tubular adenocarcinoma (GAC) using a machine learning (ML) approach. Methods Sixty-eight who underwent total gastrectomy curative (R0) resection D2-lymphadenectomy were included retrospective study. Texture features extracted from portal venous phase...
Background/Purpose: The aim of our study was to examine the factors that affect prognosis gastric cancer and evaluate effect different chemotherapy regimens on disease-free survival overall survival. Methods: This cohort retrospectively analyzed patients diagnosed with at institution between 2009 2013. demographic characteristics patients, presence Helicobacter pylori (HP), according patients' treatment protocols were examined. Results: Thirty-three women 85 men a mean age 58.6 ± 10.3 years...
Calcifying Nested Stromal-Epithelial Tumor (CNSET) of the liver is a hepatic neoplasm uncertain lineage, primarily affecting young individuals. This case report aims to elucidate clinical, histopathological, and molecular characteristics CNSET, contributing sparse knowledge regarding this unusual entity. We present here 17-year-old female patient diagnosed with highlighting tumor's radiologic appearance, surgical management, postoperative findings, alongside comprehensive review existing...
There is no systematic histopathologic analysis of non-neoplastic polyps in the gallbladder. In this study, addition to a computer search for cases designated as “polyp,” review 2533 consecutive routinely sampled archival and 203 totally submitted prospective cholecystectomies were analyzed >2 mm (cut-off was based on radiologic sensitivity). A total 447 identified. The frequency 3% 5% cases. Only 21 (5%) ≥1 cm. average age 52 years, female male ratio 3.1. Two distinct categories...
Context.— The nature and associations of gallbladder (GB) “adenomyoma” (AM) remain controversial. Some studies have attributed up to 26% GB carcinoma AMs. Objective.— To examine the true frequency, clinicopathologic characteristics, neoplastic changes in AM. Design.— Cholecystectomy cohorts analyzed were 1953 consecutive cases, prospectively with specific attention AM; 2347 archival cases; 203 totally embedded GBs; 207 GBs carcinoma; search institutions for all cases diagnosed as Results.—...
Amaç: Kolorektal kanserde KRAS mutasyonu ve tümörün lokalizasyonu ile ilişkili prognostik etki tartışmalı bir konudur.Bu nedenle 18 F-floro-2deoksi-glukoz pozitron emisyon tomografi/bilgisayarlı tomografi ( F-FDG PET/BT) görüntülemede FDG tutulum paterni kolon kanseri tanısı almış hastalarda tümör arasındaki ilişkiyi değerlendirdik.Bu üç faktörün prognoz sağkalım üzerindeki etkileri değerlendirildi
To investigate the correlation between cytology and cervical biopsy in patients with squamous cell abnormality on cytology.The smears diagnosed our clinic 2005-2008 were reviewed retrospectively. Cases which exhibited (n: 374) evaluated.The mean age was 45.15±10.78. In cytopathological results, 256 (68.4%) ASC-US, 21 (5.6%) ASC-H, 31 (8.2%) LSIL, 48 (12.8%) HSIL, 8 (4.8%) invasive carcinomas diagnosed. Histopathological results 213 (57%) nonneoplastic, 85 (22.7%) CIN I, 14 (3.7%) II,...
Colonic mucosal pseudolipomatosis is rare, and its pathogenesis controversial. A number of mechanisms, including mechanical injury during an endoscopic procedure or chemical by disinfectant, seem to contribute pathogenesis.This retrospective study examined the colonic biopsies 1370 patients. These were preserved at Department Pathology Istanbul Training Research Hospital between January 2012 June 2013.We found in 14 colonoscopy cases (1.02%). Of these patients, 8 male 6 female. The patients...
Context. Follicular cholecystitis (FC) is a poorly characterized entity. Objective. To determine its frequency/clinicopathologic associations. Design. A total of 2550 cholecystectomy specimens were examined. Two hundred three these consecutive routine cholecystectomies submitted entirely for microscopic examination to the relative frequency incidental pathologies in gallbladders (GBs). The remainder had representative sampling. Underlying conditions nonobstructive (1270 nonspecific...