A5030840416- Oral microbiology and periodontitis research
- Salivary Gland Disorders and Functions
- Infective Endocarditis Diagnosis and Management
- Bacterial Identification and Susceptibility Testing
- Periodontal Regeneration and Treatments
- Oral Health Pathology and Treatment
- Advanced biosensing and bioanalysis techniques
- Dental Implant Techniques and Outcomes
- Streptococcal Infections and Treatments
- Infectious Diseases and Tuberculosis
- Aerospace Engineering and Energy Systems
- Maritime Transport Emissions and Efficiency
- Carbon and Quantum Dots Applications
- Graphene and Nanomaterials Applications
- Gut microbiota and health
- MicroRNA in disease regulation
- Probiotics and Fermented Foods
- Oral and gingival health research
- Cancer Research and Treatments
- RNA Interference and Gene Delivery
- Circular RNAs in diseases
- Microbial infections and disease research
- Spacecraft and Cryogenic Technologies
- Advancements in Transdermal Drug Delivery
- Laser Applications in Dentistry and Medicine
Central South University
2012-2022
Second Xiangya Hospital of Central South University
2022
Southwest Minzu University
2015-2016
Shanghai Jiao Tong University
2010-2014
Shanghai Ninth People's Hospital
2010-2014
Fluorescent aptamer probes physisorbed on graphene oxide (GO) have recently emerged as a useful sensing platform. A signal is generated by analyte-induced probe desorption. To address nonspecific displacement and the false positive signal, we herein report covalently linked for adenosine triphosphate (ATP) detection. fluorophore amino dual modified was to carboxyl group GO with coupling efficiency of ∼50%. The linearity, specificity, stability, regeneration covalent sensor were...
Introduction: The aim of this study was to investigate the prevalence and molecular diversity Archaea in subgingival crevices patients with chronic periodontitis. Methods: Subgingival plaque collected from 41 periodontitis 15 healthy subjects. those samples tested by polymerase chain reaction two broad‐range archaeal primer sets. Amplicons eight ‐positive were cloned sequenced for analysis using one these sets a novel third set. Results: detected at 70.7–73.2%, but not Using set, all...
Targeted uptake of therapeutic nanoparticles in cell- or tissue-specific manner is an attractive technology since they can offer greater efficacy and reduce cytotoxicity on peripheral healthy tissues. In this study, AS1411 (AP), a DNA aptamer specifically binding to nucleolin that overexpressed the plasma membrane breast cancer (BC) cells, was exploited as targeting ligand nanoparticle-based drug delivery system. Vinorelbine (VRL) loaded PLGA-PEG (NP) were formulated by emulsion/solvent...
Periodontitis is a common chronic oral disease among the world. Periodontal ligament stem cells (PDLSCs) has been proved to be promising tool for treatment of periodontitis due their capability generating periodontal tissues. Circ_0087960 and KDM5B have shown participate in process osteogenic differentiation with unclear function mechanism.Circ_0087960 expressions were detected during induction PDLSCs. The functions circ_0087960 validated by manipulating expression shRNA. ChIP luciferase...
Porphyromonas gingivalis strain SJD2 was isolated from subgingival plaque of a patient in China with chronic periodontitis. Here, we report the draft genome this strain, size 2,328,850 bp, average G+C content 48.3%, and 2,020 predicted protein-coding sequences.
DGGE of 16S rDNA is one the most frequently used methods to study microbial communities. In this study, profiles different regions periodontal pathogens Porphyromonas gingivalis, Fusobacterium nucleatum, and Prevotella nigrescens were investigated. The results suggested that V3-V5 V6-V8 fragments may be suitable for community analysis subgingival bacteria. Further samples with as target that, in chronic periodontitis, re-colonization by bacteria a population very similar baseline occur 6...
The incidence of bone and joint tuberculosis is the highest in extrapulmonary tuberculosis, accounting for 3%-5% all TB cases 35%-50% tuberculosis. Currently, clinical treatment generally excision necrotic lesions then putting anti-tuberculosis drugs to clear residual tubercle bacillus. However, drug powders within will soon be washed away by body fluids. Sustained loaded scaffolds would on one hand recover remaining defect rebuild tissues other offer sustained local release desired places....