A5089912030- Infant Nutrition and Health
- Digestive system and related health
- Plant biochemistry and biosynthesis
- Microbial Natural Products and Biosynthesis
- Probiotics and Fermented Foods
- Gut microbiota and health
- Enzyme Structure and Function
- Milk Quality and Mastitis in Dairy Cows
- RNA Interference and Gene Delivery
- Photosynthetic Processes and Mechanisms
- Extracellular vesicles in disease
- Insect Utilization and Effects
- Agriculture Sustainability and Environmental Impact
- Nutritional Studies and Diet
- Biochemical and Molecular Research
- Folate and B Vitamins Research
- Animal health and immunology
- Muscle metabolism and nutrition
- MicroRNA in disease regulation
- Protein Hydrolysis and Bioactive Peptides
- Diet and metabolism studies
- RNA modifications and cancer
- Microbial Metabolism and Applications
Morinaga (Japan)
2014-2023
Hokkaido University
2008-2013
To identify the genes for biosynthesis of off-flavor terpenoid alcohol, 2-methylisoborneol (2-MIB), key encoding monoterpene cyclase were located in bacterial genome databases by using a combination hidden Markov models, protein-family search, and sequence alignment their gene products. Predicted terpene cyclases classified into three groups: sesquiterpene, diterpene, other cyclases. Genes group that form an operon with S-adenosyl-l-methionine (SAM)-dependent methyltransferase found data...
The INFOGEST method is a valuable tool for understanding and monitoring food digestion as an alternative to in vivo assays. However, few studies have compared animal protein sources terms of quality using the method. This study aimed evaluate milk-, plant-, insect-based materials by vitro digestibility digestible indispensable amino acid score (DIAAS), following Milk-based had highest (86.1-90.8%), followed soy (85.1%) wheat (82.3%). These significantly higher with zein (65.1%), cricket...
Abstract It is important to provide formula-fed infants with a bifidobacteria-enriched gut microbiota similar those of breastfed ensure intestinal health. Prebiotics, such as certain oligosaccharides, are useful solution this problem, but the combinational benefits these oligosaccharides have not been evaluated. This study investigated oligosaccharide combinations and screened for an optimal combination promote healthy infants. In vitro in vivo experiments were performed assess bifidogenic...
Bifidobacteria are considered beneficial for infant health, however, they less prevalent in gut microbiota of formula-fed than breast-fed infants. This study investigated the bifidogenic effects cow's glycomacropeptide (GMP) and metabolic enzymes that Bifidobacterium bifidum JCM1254 uses when grown GMP-containing medium. was able to be medium, growth abolished glycans were chemically cleaved. Abundance carbohydrate metabolism-related proteins, including sialidase, higher cultured medium...
In the typical isoprenoid-biosynthesis pathway, condensation of universal C 5 -unit precursors isopentenyl pyrophosphate (IPP) and dimethylallyl (DMAPP) occurs via common intermediates prenyl pyrophosphates (C 10 –C 20 ). The diversity isoprenoids reflects differences in chain length, cyclization further additional modification after cyclization. contrast, biosynthesis 2-methylisonorneol (2-MIB), which is responsible for taste odour problems drinking water, unique that it primes enzymatic...
Hand-reared elephant calves that are nursed with milk substitutes sometimes suffer bone fractures, probably due to problems associated nutrition, exercise, sunshine levels and/or genetic factors. As we were expecting the birth of an Asian (Elephas maximus), analyzed elephant's breast improve for calves. Although there few nutritional differences between conventional and milk, found a large unknown peak in during high-performance liquid chromatography-based amino acid analysis determined it...
We recently reported that plasma albumin redox state, which correlates with synthesis rate, could be associated the quality of dietary protein. Aiming to elucidate association between them, state was investigated in rats fed various kinds AIN-93G-based low protein diets. Plasma shifted a more oxidized 3% casein (CN) diet than those whey or wheat gluten diet, while supplementing CN cystine reversed it reduced indicating would complement shortage cysteine CN, thereby increasing rate....
The biosynthetic pathway of the off-flavour terpenoid alcohol 2-methylisoborneol (2-MIB) requires geranyl pyrophosphate methyltransferase (GPPMT) to methylate GPP before cyclization reaction. GPPMT is first example an S-adenosyl-L-methionine-dependent that acts on general intermediates such as and farnesyl in isoprenoid pathways. In this study, recombinant was overproduced, purified crystallized absence presence cofactor, cofactor analogue substrate. Well diffracting crystals apo containing...
<h3></h3> Non-digestive oligosaccharides are often added to infant formula help formula-fed infants develop an intestinal microbiota composed predominantly of Bifidobacteria, similar that breast-fed infants. Because various types exhibit specific microbial metabolism, the combined usage is considered provide additive or synergistic effects for Bifidobacteria growth in microbiota. The aim this study was evaluate effect lactulose, raffinose, and galacto-oligosaccharide (GOS) on...