A5056641311- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- Livestock and Poultry Management
- Single-cell and spatial transcriptomics
- Autophagy in Disease and Therapy
- Animal Nutrition and Physiology
- Adipose Tissue and Metabolism
- Phytochemical Studies and Bioactivities
- Neurogenesis and neuroplasticity mechanisms
- CRISPR and Genetic Engineering
- Botanical Research and Chemistry
- RNA regulation and disease
- Traditional and Medicinal Uses of Annonaceae
- Genetic diversity and population structure
- Genetic Mapping and Diversity in Plants and Animals
- Chromosomal and Genetic Variations
- Sirtuins and Resveratrol in Medicine
- Neuroinflammation and Neurodegeneration Mechanisms
Kunming Institute of Zoology
2017-2025
Chinese Academy of Sciences
2017-2025
Yunnan Academy of Agricultural Sciences
2022
University of Chinese Academy of Sciences
2021
Skolkovo Institute of Science and Technology
2020-2021
Shaanxi Provincial People's Hospital
2017
Comparative analysis of primate genomes within a phylogenetic context is essential for understanding the evolution human genetic architecture and diversity. We present such study 50 species spanning 38 genera 14 families, including 27 first reported here, with many from previously less well represented groups, New World monkeys Strepsirrhini. Our analyses reveal heterogeneous rates genomic rearrangement gene across lineages. Thousands genes under positive selection in different lineages play...
Numerous biological functions of long intergenic non-coding RNAs (lincRNAs) have been identified. However, the contribution lincRNAs to domestication process has remained elusive. Following from their wild ancestors, animals display substantial changes in many phenotypic traits. Therefore, it is possible that diverse molecular drivers play important roles this process.We analyzed 821 transcriptomes study and annotated 4754 lincRNA genes chicken genome. Our population genomic analysis...
Piao chicken, a rare Chinese native poultry breed, lacks primary tail structures, such as pygostyle, caudal vertebra, uropygial gland, and feathers. So far, the molecular mechanisms underlying absence in this breed remain unclear. In study, we comprehensively employed comparative transcriptomic genomic analyses to unravel potential genetic underpinnings of rumplessness chicken. Our results reveal many biological factors involved development several regions under strong positive selection...
The evolutionary and functional features of RNA editing are well studied in mammals, cephalopods, insects, but not birds. Here, we integrated transcriptomic whole-genomic analyses to exhaustively characterize the expansive repertoire adenosine-to-inosine (A-to-I) sites (RESs) chicken. In addition, investigated status chicken editome as a potential mechanism domestication. We detected lowest level liver chickens, compared muscles humans, found higher activity specificity brain than non-neural...
Abstract Piao chicken, a rare Chinese native poultry breed, lacks primary tail structures, such as pygostyle, caudal vertebra, uropygial gland and feathers. So far, the molecular mechanisms underlying absence in this breed have remained unclear. We employed comprehensive comparative transcriptomic genomic analyses to unravel potential genetic underpinnings of rumplessness chicken. Our results reveal many biological factors involved development several regions under strong positive selection...