- Cannabis and Cannabinoid Research
- Diet, Metabolism, and Disease
- Muscle metabolism and nutrition
- Cardiovascular and exercise physiology
- Adipose Tissue and Metabolism
- Exercise and Physiological Responses
- Biochemical Analysis and Sensing Techniques
- Magnesium in Health and Disease
- Coffee research and impacts
- Pharmacological Effects and Assays
- Circadian rhythm and melatonin
- Pancreatic function and diabetes
- Thermoregulation and physiological responses
- Neuroscience of respiration and sleep
- Heart Rate Variability and Autonomic Control
- Therapeutic Uses of Natural Elements
- Alcohol Consumption and Health Effects
- Physical Activity and Health
- Nutrition and Health in Aging
- Sports Performance and Training
- Diet and metabolism studies
- Diabetes Treatment and Management
- Travel-related health issues
- Cardiovascular Effects of Exercise
- Pharmacology and Obesity Treatment
Colorado State University
2020-2025
American College of Sports Medicine
2023
Cannabidiol (CBD) is widely available and marketed as having therapeutic properties. Over-the-counter CBD unregulated, many of the claims lack scientific support, controversy exists to safety CBD-liver interaction. The study aims were compare pharmacokinetics commercial metabolites following ingestion five different formulations, determine influence on food induced thermogenesis, pharmacokinetics, markers liver function. Fourteen males (body mass index ≥ 25 kg/m2) studied in a...
Data supporting the physiological effects of cannabidiol (CBD) ingestion in humans are conflicting. Differences between CBD preparations and bioavailability may contribute to these discrepancies. Further, an influence body composition on is feasible, but currently undocumented. The aims this study were to: (1) compare pharmacokinetics five oral over 4 h; (2) examine relationship pharmacokinetics; and, (3) explore heart rate variability. In total, CBD, standardized 30 mg, orally administered...
Background/Objectives: Although the importance of magnesium for overall health and physiological function is well established, its influence on exercise performance less clear. The primary study objective was to determine short-term supplementation cycle ergometer performance. hypothesis that would elicit an ergogenic effect. Methods: A randomized, double-blind, placebo-controlled, two-period crossover design used men women who were regular exercisers. Fifteen participants ingested either a...
The purpose of this study was to investigate the potential ergogenic effects an oral lactate supplement. For double-blind, randomized, placebo-controlled crossover design, fifteen recreational exercisers (nine males, six females) ingested a placebo or commercially available supplement prior cycle ergometer exercise. Primary outcomes included peak oxygen uptake (VO2peak; via indirect calorimetry), VO2 at ventilatory threshold, and work rate threshold (arterialized venous blood from heated...
The purpose of the study was to describe and compare pharmacokinetics five commercial edible marijuana products, determine influence body composition on pharmacokinetics, and, in light epidemiology suggesting may offer diabetes protection, explore glucose tolerance. Seven regular users self-administered products a randomized crossover design; each product contained 10 mg delta-9-tetrahydrocannabinol (THC). Thirty minutes following ingestion, participants imbibed 75 g beverage. Time-to-peak...
Purpose: There is extensive public and scientific interest in the influence of cannabis psychoactive cannabinoid, delta-9-tetrahydrocannabinol (THC), on exercise performance. Unfortunately, recent, up-to-date studies are lacking. The aim current study was to address hypothesis that ingestion edible marijuana, prior exercise, would have unfavorable effects physiological response Methods: 17 Healthy adult male female habitual exercisers, who were regular users products, screened for...
Sedentary obesity is associated with increased risk of many cardio-metabolic diseases, including type 2 diabetes. Weight loss therefore a desirable goal for sedentary adults obesity. also well-documented side effect sodium glucose co-transporter (SGLT2) inhibition, pharmaceutical strategy diabetes treatment. We hypothesized that, compared placebo, SGLT2 inhibition as an adjunct to out-patient dietary counselling weight would lead more favorable modification body mass and composition, greater...
ABSTRACT Introduction The release of interleukin (IL)-6 from contracting skeletal muscle is thought to contribute some the health benefits bestowed by exercise. This IL-6 response seems proportional exercise volume and lactate production. Unfortunately, high volumes are not feasible for all people. Caffeine augments magnitude increase in circulating high-intensity long-duration also increases concentrations during We hypothesized that caffeine, ingested before short-duration,...
The purpose of the study was to describe and compare pharmacokinetics five commercial edible marijuana products, determine influence body composition on pharmacokinetics, and, in light epidemiology suggesting may offer diabetes protection, explore glucose tolerance. Seven regular users self-administered products a randomized crossover design; each product contained 10mg delta-9-tetrahydrocannabinol (THC). 30-minutes following ingestion, participants imbibed 75g beverage. Time-to-peak plasma...
Brown fat is a thermogenic tissue that may have therapeutic value for the treatment of obesity and diabetes. That brown under sympathetic control indisputable, but considerable controversy exists as to which beta-adrenergic receptor subtypes, b 1 AR, 2 AR or 3 primary regulator. The purpose current study was determine if co-administration agonist, mirabegron, would increase energy expenditure activation more than non-selective bAR stimulation (isoproterenol) alone. 14 healthy, active young...
In light of the many demands competing for our attention in today’s modern lifestyle, scheduling healthy behaviors, such as daily exercise, at or around same time day can be difficult. Accordingly, purpose this study was to compare endurance benefits short‐term sprint interval training (SIT) when SIT completed a constant variable day. The influence assessment relative also examined. consisted six sessions 4‐to‐7 x 30‐second sprints on stationary cycle ergometer over two weeks. Endurance...
The release of interleukin 6 (IL-6) from contracting skeletal muscle is thought to contribute some the health benefits bestowed by exercise. This IL-6 response appears proportional exercise volume. Unfortunately, high volumes are not feasible for all people. Caffeine augments magnitude increase in circulating concentration high-intensity and long-duration exercise, men. also known concentrations lactate during One mechanisms exercising production. We hypothesized that caffeine, ingested...
The thermic effect of feeding (the increase in energy expenditure above resting metabolic rate following ingestion food) is lower adult humans with overweight and obesity compared to their lean counterparts. In animal models obesity, the endocannabinoid system upregulated thought contribute an unfavorable phenotype. influence cannabidiol, a non-psychoactive component Cannabis sativa L., on thermogenic properties unclear. Accordingly, purpose current study was explore hypothesis that acute...