Chen Deng

ORCID: 0000-0001-8233-8723
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About
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Research Areas
  • Epilepsy research and treatment
  • Dental Implant Techniques and Outcomes
  • Periodontal Regeneration and Treatments
  • Pharmacological Effects and Toxicity Studies
  • EEG and Brain-Computer Interfaces
  • Radiomics and Machine Learning in Medical Imaging
  • MRI in cancer diagnosis
  • Dental materials and restorations
  • Neonatal and fetal brain pathology
  • Advanced MRI Techniques and Applications
  • Maternal and fetal healthcare
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Liver Disease Diagnosis and Treatment
  • Reconstructive Surgery and Microvascular Techniques
  • Ectopic Pregnancy Diagnosis and Management
  • Neuroscience and Neuropharmacology Research
  • Dental Radiography and Imaging
  • Functional Brain Connectivity Studies
  • Pneumonia and Respiratory Infections
  • ECG Monitoring and Analysis
  • Cardiac Arrest and Resuscitation
  • Melanoma and MAPK Pathways
  • Facial Trauma and Fracture Management
  • Pancreatitis Pathology and Treatment
  • Advanced Neuroimaging Techniques and Applications

Sichuan University
2016-2025

National Clinical Research
2025

State Key Laboratory of Oral Diseases
2025

Frontier Science Foundation
2025

West China Hospital of Sichuan University
2017-2025

Chengdu Women's and Children's Central Hospital
2021-2024

University of Electronic Science and Technology of China
2021-2024

Philips (China)
2023

Third Xiangya Hospital
2018-2019

Central South University
2010-2019

To evaluate the value of 24-hour video-EEG (VEEG) in assessing recurrence risk after a first unprovoked seizure.Consecutively 134 patients with epileptic seizure were recuited from West China Hospital, Sichuan University, between January 2010 and 2013. All underwent VEEG magnetic resonance imaging (MRI) brain, Each patient had at least 24-month follow up.Seventy-six (56.7%) abnormal VEEG, abnormalities was associated an increased (RR 2.84, 95% CI 1.67-4.82, p<0.001). The overall accumulated...

10.1016/j.seizure.2016.06.005 article EN publisher-specific-oa Seizure 2016-06-15

Abstract The overexpression of cyclic AMP (cAMP)–dependent protein kinase (PKA) has been reported in patients with cancer, and PKA inhibitors have tested clinical trials as a novel cancer therapy. present study was designed to characterize the population distribution extracellular activity cAMP-dependent (ECPKA) its potential value biomarker for detection monitoring ECPKA determined serum samples from Chinese consisting total 603 subjects (374 normal healthy volunteers 229 patients). by...

10.1158/1055-9965.epi-06-0367 article EN Cancer Epidemiology Biomarkers & Prevention 2007-04-01

To evaluate the dimensional reduction of peri-implant hard tissues and esthetic outcome after immediate implant placement (IIP) in zone. Patients who received IIP with bone grafts zone, either or delayed restoration, were included this retrospective cohort study. The implants categorized into three groups based on labial thickness (LBT) before implantation: Group 1 (≤ 0.5 mm), 2 (0.5-1 3 (≥ mm). horizontal loss (HBL) at 0, 3, 5 mm apical to shoulder, marginal (MBL), Pink Esthetic Score (PES)...

10.1111/cid.13439 article EN Clinical Implant Dentistry and Related Research 2025-02-01

Effective management of inflammation is one the promising strategies to prevent formation chronic wounds. Despite hydrogen being a prospective molecule for anti-inflammatory effects, on-demand delivery that could synchronize with dynamic stages has yet remained unaddressed. Moreover, its specific immunomodulatory mechanisms are still veiled. In this study, we introduced ISO-ZIF-8@AB, hydrogen-generating nanoplatform integrated visible-light photocatalysis and hydrolysis reactions achieve...

10.1021/acsami.5c00667 article EN ACS Applied Materials & Interfaces 2025-03-21

ABSTRACT Aim This study aimed to assess the effectiveness of a treatment strategy involving only implant restoration first molars (M1s) in cases where both M1s and second (M2s) lost. Materials Methods A retrospective design compared two groups: one underwent simultaneous M2s (Group 1), while other 2). Statistical models were used evaluate survival, complication‐free survival rates, cumulative costs, peri‐implant conditions, patient‐reported outcomes (PROMs). Results included 247 patients,...

10.1111/clr.14444 article EN Clinical Oral Implants Research 2025-05-01

ABSTRACT Objectives To investigate the clinically acceptable deviation threshold and factors associated with trueness across three computer‐assisted implant surgery (CAIS) approaches: static CAIS (s‐CAIS), dynamic (d‐CAIS), robotic (r‐CAIS). Materials Methods A total of 314 implants in 194 patients were retrospectively included, preoperative postoperative CBCT scans collected. Outcome measures included platform, apex, angular deviations, which assessed by registering to plans using a jawbone...

10.1111/clr.14458 article EN Clinical Oral Implants Research 2025-06-03

This study was conducted to develop a population pharmacokinetic (PopPK) model for vancomycin and detect the significant covariates that influence PopPKs facilitate individualized therapy Chinese pediatric patients.Patients ≤ 10 years old who received ≥ 72 hours between 2007 2010 were analyzed using nonlinear mixed-effects modeling approach (-NONMEM). A one-compartment with first-order elimination chosen depict data. Stepwise covariate (SCM) employed obtain final model. Internal validation...

10.5414/cp202835 article EN International Journal of Clinical Pharmacology and Therapeutics 2017-03-03

This paper describes the utility of dynamic bifurcation control for suppressing a pathological period-2 rhythm (cardiac alternans) in an atrioventricular modal conduction model. A commonly held view has linked alternans rhythms this model to period-doubling bifurcations. Our analysis shows that is actually associated with period-1 border-collision bifurcation. In design, we employ feedback incorporating washout filter suppress cardiac alternans. Important features law include equilibrium...

10.1109/iscas.1998.704092 article EN 2002-11-27

Abstract Objectives. Kaiser scoring system for breast magnetic resonance imaging (bMRI) is a clinical decision-making tool in diagnosing lesions. However, the score (KS) did not include evaluation of vascularity. Therefore, this study aimed to using KS combined with vascular assessment,defined as * , and investigate effectiveness differentiating benign from malignant Methods. This retrospective included 223 patients suspicious lesions pathologically verified results. The histopathological...

10.21203/rs.3.rs-2783493/v1 preprint EN cc-by Research Square (Research Square) 2023-04-17

The Kaiser scoring system for breast magnetic resonance imaging is a clinical decision-making tool diagnosing lesions. However, the score (KS) did not include evaluation of vascularity. Therefore, this study aimed to use KS combined with vascular assessment, defined as KS*, and investigate effectiveness KS* in differentiating benign from malignant lesions.This retrospective included 223 patients suspicious lesions pathologically verified results. histopathological diagnostic criteria were...

10.3389/fonc.2023.1165405 article EN cc-by Frontiers in Oncology 2023-07-06

Although overt hepatic encephalopathy (OHE) patients were shown to have bilaterally symmetrical structural and functional abnormalities in the whole brain, few studies focused on bilateral cerebral hemisphere commissural fibers measured coordination between hemispheres. This study aimed investigate changes of corpus callosum (CC) interhemispheric with OHE test hypothesis that abnormal CC induced by impairs cirrhosis patients.The microstructural integrity volumes each subregion analyzed...

10.21037/atm-21-5109 article EN Annals of Translational Medicine 2021-10-01
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