A5100459952- Circular RNAs in diseases
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Eicosanoids and Hypertension Pharmacology
- Gastric Cancer Management and Outcomes
- BRCA gene mutations in cancer
- Axon Guidance and Neuronal Signaling
- Adipose Tissue and Metabolism
- Minerals Flotation and Separation Techniques
- Natural product bioactivities and synthesis
- Nanoplatforms for cancer theranostics
- Drug Transport and Resistance Mechanisms
- Immune Cell Function and Interaction
- Wnt/β-catenin signaling in development and cancer
- Nutrition, Genetics, and Disease
- Biological Activity of Diterpenoids and Biflavonoids
- Genetic Mapping and Diversity in Plants and Animals
- Hops Chemistry and Applications
- Gene expression and cancer classification
- Cancer Mechanisms and Therapy
- Peroxisome Proliferator-Activated Receptors
- Network Security and Intrusion Detection
- Neurological Disease Mechanisms and Treatments
- T-cell and B-cell Immunology
- Elevator Systems and Control
Nanjing University of Chinese Medicine
2023
Fudan University
2001-2022
Minhang District Central Hospital
2013-2022
Guangdong Province Women and Children Hospital
2020
Tianjin Medical University
2020
First Affiliated Hospital of Zhengzhou University
2010-2019
First Affiliated Hospital of Chengdu Medical College
2015
Shanghai Institutes for Biological Sciences
2015
Chinese Academy of Sciences
2015
Chinese People's Armed Police Force
2013-2014
Background/Aims: Gastric neuroendocrine tumors (G-NETs) are uncommon neoplasms that can present with or without clinical symptoms. In this study, we evaluated the incidence, prognosis, and temporal trends of G-NETs. Methods: We analyzed all cases G-NETs registered in Surveillance, Epidemiology, End Results (SEER) database from 1973 to 2014. Incidence was estimated by age joinpoint analyses. Survival rates were calculated survival over time evaluated. Results: A total 3740 eligible patients...
High mobility group proteins (HMGs) are the second most abundant chromatin and exert global genomic functions in establishment of active or inactive domains. Through interaction with nucleosomes, transcription factors, nucleosome-remodeling machines histones, HMGs family contribute to fine tuning response rapid environmental changes. Mammalian high Bs (HMGBs) characterized by two tandem HMG box domains followed a long acidic tail. Recent studies demonstrated that expression HMGBs has been...
Numerous studies reveal that circular RNAs (circRNAs) affect cancer progression. CircWHSC1 is a novel circRNA accelerates ovarian Nevertheless, the function of circWHSC1 in regulating breast (BC) elusive. Here, quantitative reverse transcription-polymerase chain reaction (qRT-PCR) was carried out to detect profiles and miR-195-5p BC tissues corresponding non-tumor tissues. Gain- loss-of-function assays were implemented both vivo ex verify significance development. cell proliferation...
Abstract Bulk nanobubbles fascinate scientists because of their stability over long periods time and ability to carry gases, leading numerous potential applications. Considering the hypoxic tumor microenvironment advantages bulk nanobubbles, lipid‐encapsulated oxygen are prepared from free in this study. The obtained carrier is then modified with a protein fused single‐chain antibody human epidermal growth factor receptor 2 (anti‐HER2 scFv) tandem‐repeat cytochrome c scFv‐nCyt ) enhance...
Damage to endothelial cells is a key event in the pathogenesis of atherosclerosis and vascular disease. This study aimed determine whether free fatty acids (FFAs) induced oxidative stress apoptosis human brain microvascular (HBMVECs) vitro and, if so, which signalling pathway mediated these effects. After culture different concentrations FFAs for 24-72 h, cell viability/proliferation was determined using counting kit, detected by measuring caspase-3 activity annexin V-conjugated fluorescein...
// Rong-liang Shi 1,2,3,* , Qian Chen 1,* Zhen Yang 1 Gaofeng Pan Ziping Zhang WeiHua Wang 1,4 Shaoqun Liu Dongbin Daowen Jiang and Weiyan Department of General Surgery, Minhang Hospital, Fudan University, Shanghai, People’s Republic China 2 Head Neck University Shanghai Cancer Center, 3 Oncology, Medical College, 4 Thoracic * These authors have contributed equally to this work Correspondence to: Liu, email: Jiang, Keywords : gastric cancer, marital status, SEER,survival analysis...
The concept of negative lymph node (NLN) counts has recently attracted attention as a prognostic indicator in various cancer. However, the correlation between NLN and patient prognosis setting gastric cancer is not fully studied. Surveillance, Epidemiology, End Results Program (SEER)-registered patients were used for analysis this study. Clinicopathological characteristics, including race, age, gender, tumor stage, grade, cause specific survival collected. Univariate multivariate Cox...
Recent advances in the understanding of microRNA have rendered microRNAs (miRNAs) a compelling novel class biomarker cancer biology. However, specific function miRNA‑18a (miR‑18a) colorectal (CRC) remains unclear. In present study, role miR‑18a carcinogenesis CRC was investigated. expression assessed specimens and cell lines using reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR). The targets were predicted bioinformatics tools. Luciferase reporter assays used to confirm...
Deep venous thrombosis (DVT) constitutes a great threat to health worldwide. Endothelial cell injury and dysfunction comprise the critical contributor for development of DVT. However, mechanism behind it remains poorly elucidated. The study is aimed at investigating role microRNA-122 (miR-122) oxidative stress on results showed that miR-122 overexpression dampened H2O2-evoked cytotoxic in human umbilical vein endothelial cells (HUVECs) by increasing viability, suppressing apoptosis injury....
In an actual concrete dam construction, the efficiency of thermal field reconstruction directly affects timeliness temperature control measures. Therefore, using lightweight methods to obtain real-time, accurate fields is crucial for control. To balance both accuracy and efficiency, this study proposes optimization method in dams. The consists three components: evaluating interpolation algorithms, optimizing number monitoring points, analyzing their positions. Specifically, a distributed...
Objective To study the expression of RhoA protein in colorectal carcinoma. Methods The 92 cases ccarcinoma and 30 normal rectal tissue was detected by SP immunohistochemical technique. Results were negative 40 tissue. In carcinoma, positive rate 70.7%. It significantly higher than that high-differentiated 、moderate-differentiated lowdifferentiated carcinoma 43.5% 、74.4% 86.7% ,respectively(P ＜0.05). rates phase Ⅰ、phase Ⅱ、phase Ⅲ Ⅳ 48.6% 、77.3% 、83.3% 94.1%, respectively (P ＜ 0.05).The...
Objective To investigate the association between microRNA5 (miRNA, miR)-675 expression level in tumor tissues and adjacent from patients with gastric cancer prognosis. Meanwhile, to explore influence of miR-675 carcinoma (SGC-7901) cells. Methods The miRNA data TCGA databases were collected, survival time was analyzed according tissues. Real-time quantitative reverse transcriptase-polymerase chain reaction (RT-qPCR) used detect 30 non-tumor Cell counting assay kit-8 (CCK-8) analyze...