- Protist diversity and phylogeny
- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Computational Drug Discovery Methods
- Machine Learning in Bioinformatics
- RNA and protein synthesis mechanisms
- Marine and coastal ecosystems
- Cancer Genomics and Diagnostics
- Polar Research and Ecology
- vaccines and immunoinformatics approaches
- Environmental DNA in Biodiversity Studies
European Bioinformatics Institute
2024
Adigrat University
2017
Università di Camerino
2010-2016
We report the characterization of bacterial consortium associated to Euplotes focardii, a strictly psychrophilic marine ciliate that was maintained in laboratory cultures at 4 °C after its first isolation from Terra Nova Bay, Antarctica. By Illumina genome analyser, we obtained 11,179 contigs potential prokaryotic origin and classified them according NCBI's attributes table. The majority these sequences correspond either Bacteroidetes (16 %) or Proteobacteria (78 %). latter were dominated by...
Abstract The European Nucleotide Archive (ENA, https://www.ebi.ac.uk/ena), maintained at the Molecular Biology Laboratory's Bioinformatics Institute (EMBL-EBI) provides freely accessible services, both for deposition of, and access to, open nucleotide sequencing data. Open scientific data are of paramount importance to community contribute daily acceleration advance. Outlined here changes updates on ENA service in 2024, aligning with broad goals enhancing interoperability, globalisation...
Abstract We identified two ice-binding protein (IBP) sequences, named EFsymbAFP and EFsymbIBP, from a putative bacterial symbiont of the Antarctic psychrophilic ciliate Euplotes focardii . is 57.43% identical to antifreeze (AFP) Stigmatella aurantiaca strain DW4/3-1, which was isolated Victoria Valley lower glacier. EFsymbIBP 53.38% IBP Flavobacteriaceae bacterium 3519-10, glacial ice Lake Vostok. are 31.73% at amino acid level organized in tandem on chromosome. The relatively low sequence...
Malaria is a major killer disease causing heavy loss in terms of life and medical expenditure. The genome Plasmodium falciparum sequenced 2002 but more than 60% its meaning still remains unknown. We compared protein sequences from P. the genomic with vivax knowlesi through standalone blast tool NCBI. found many proteins annotated one species sharing high similarity unannotated other/s species. Based on 'annotation transfer by homology' method we 715 hypothetical proteins. By latest...
Malaria is a major killer disease causing heavy loss in terms of life and medical expenditure. The genome Plasmodium falciparum sequenced 2002 but more than 60% its meaning still remains unknown. We compared protein sequences from P. the genomic with vivax knowlesi through standalone blast tool NCBI. found many proteins annotated one species sharing high similarity unannotated other/s species. Based on 'annotation transfer by homology' method we 715 hypothetical proteins. By latest...