A5082554330- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- Photosynthetic Processes and Mechanisms
- Enzyme Structure and Function
- Peptidase Inhibition and Analysis
- Fungal and yeast genetics research
- Lipoproteins and Cardiovascular Health
- Plant Stress Responses and Tolerance
- RNA Research and Splicing
- Diet and metabolism studies
- Cancer, Lipids, and Metabolism
- Vibrio bacteria research studies
- Metabolism, Diabetes, and Cancer
- Mitochondrial Function and Pathology
- Plant Gene Expression Analysis
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pancreatic function and diabetes
Charmo University
2020-2023
Iraq University College
2023
The University of Western Australia
2019-2022
Australian Research Council
2022
ARC Centre of Excellence in Plant Energy Biology
2019-2021
University of Sulaimani
2019
Abiotic stress in plants causes accumulation of reactive oxygen species (ROS) leading to the need for new protein synthesis defend against ROS and replace existing proteins that are damaged by oxidation. Functional plant ribosomes critical these activities, however we know little about impact oxidative on ribosome abundance, turnover, function. Using Arabidopsis cell culture as a model system, induced using 1 µm H2 O2 or 5 menadione more than halve growth rate limit total content. We show...
Lipids are considered as organic substances that relatively insoluble in water while soluble solvents such alcohol and ether. Unlike carbohydrates, proteins nucleic acids, lipids not polymers. Further, mostly small molecules. More than 90% of the fatty acids found plasma form acid esters primarily triacylglycerol, cholesteryl esters. can be exogenously from dietary sources endogenously mainly liver. Due to insolubility lipids, so circulation blood is performed by actions several transport...
Significance Photoinhibitory high light stress in plants leads to increases markers of protein degradation and transcriptional up-regulation proteases proteolytic machinery, but homeostasis (proteostasis) most enzymes is largely maintained under light, so we know little about the metabolic consequences it beyond photosystem damage. We developed a technique look for rapid turnover events response through 13 C partial labeling detailed peptide mass spectrometry. This analysis reveals...
Abstract Cholera is a disease caused by Gram-negative bacterium Vibrio cholerae and among the significant threats to global public health. The mainly spread in hot months of year; low sanitation lack clean water are major causes disease. In this study, we conducted molecular epidemiological study recent outbreak city Sulaymaniyah Iraq. Based on bacteriological, serological, identification bacterium, it was shown that V. O1 serotype Ogawa Additionally, number positive cholera cases were...
Abstract The cytosolic 80S ribosome is composed of protein and RNA molecules its function in synthesis modulated through interaction with other components. Defining the role each proteins associated ribosomes plants a major challenge which hampered by difficulties attribution different to roles biogenesis, mature (r-proteins) or broader translatome functioning ribosomes. Here we refined core r-protein composition determining abundance low, partially highly purified ribosomal samples from...
Abstract Photo-inhibitory high light stress in Arabidopsis leads to increases markers of protein degradation and transcriptional upregulation proteases proteolytic machinery, but proteostasis is largely maintained. We find significant the vivo rate for specific molecular chaperones, nitrate reductase, glyceraldehyde-3 phosphate dehydrogenase, phosphoglycerate kinase other plastid, mitochondrial, peroxisomal, cytosolic enzymes involved redox shuttles. Coupled analysis rates, mRNA levels,...
Carbohydrates are the major source of energy for living cells, they first cellular constituents that synthesized during photosynthesis from carbon dioxide and water by green plants through absorption sun light. To be used as energy, carbohydrates compounds should undergo series enzymatic metabolic stages in cell. Beside productions, catabolism provides different intermediates molecules synthesis biomolecules like fatty acids, amino DNA, RNA. Among three main examples monosaccharide (i.e:...
The Receptor for Activated C Kinase 1 (RACK1) protein is one of the ribosomal proteins that located in small subunit which maintained across most eukaryotes and functions as a flexible scaffold involved multiple signaling pathways. It considered highly conserved found wide range tryptophan-aspartate (WD40) repeat eukaryotic organisms, from Chlamydomonas to plants mammals. RACK1 adopts propeller structure with seven blades structures, enabling binding capability protein. participates...