A5100435797- Traditional Chinese Medicine Analysis
- Traditional Chinese Medicine Studies
- Acupuncture Treatment Research Studies
- Neurological Disease Mechanisms and Treatments
- Medical Research and Treatments
- Healthcare and Venom Research
- Metabolomics and Mass Spectrometry Studies
- Cardiovascular and exercise physiology
- Ginseng Biological Effects and Applications
- Ovarian function and disorders
- Medicinal Plant Pharmacodynamics Research
- Inflammatory mediators and NSAID effects
- Natural product bioactivities and synthesis
- Natural Compounds in Disease Treatment
- Medicinal Plants and Bioactive Compounds
- Plant-based Medicinal Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Heart Rate Variability and Autonomic Control
- Histone Deacetylase Inhibitors Research
- Biofield Effects and Biophysics
- Plant Reproductive Biology
- Medicinal Plants and Neuroprotection
- Ginkgo biloba and Cashew Applications
- Pharmacological Effects of Natural Compounds
- Flavonoids in Medical Research
Shanghai University of Traditional Chinese Medicine
2006-2025
Seventh People's Hospital of Shanghai
2020-2025
University of Chinese Academy of Sciences
2024
Shandong Agricultural University
2024
Anhui University of Traditional Chinese Medicine
2022-2023
Xuzhou Medical College
2008-2023
Beijing University of Chinese Medicine
2023
The First People’s Hospital of Lianyungang
2023
Second People’s Hospital of Huai’an
2017-2023
Tianjin University of Traditional Chinese Medicine
2014-2023
Angiogenesis and vasculogenic mimicry (VM) are thought to be the predominant processes ensuring tumor blood supply during growth metastasis of glioblastoma (GBM). Celastrol has potential anti-glioma effects, however mechanisms underlying these effects remain unclarified. Recent studies have shown that PI3K/Akt/mTOR signaling pathway is closely related angiogenesis VM formation. In present study, we demonstrated, for first time, celastrol eliminated formation by blocking this in glioma cells....
Growing evidence has demonstrated exercise as an effective way to promote cardiovascular health and protect against diseases However, the underlying mechanisms of beneficial effects have yet be elucidated. Animal studies are widely used investigate key exercise-induced protection. standardized procedures well-established evaluation indicators for animal models needed guide researchers in carrying out effective, high-quality using prevent treat diseases. In our review, we present commonly...
Moutan Cortex (MC) is a traditional Chinese medicine that contains abundant medicinal components, such as paeonol, paeoniflorin, etc. Paeonol the main active component of MC. In this study, paeonol was extracted from MC through an ultrasound-assisted extraction process, which based on single-factor experiments and response surface methodology (RSM). Subsequently, eight macroporous resins different properties were used to purify The components purified extract identified by ultra-performance...
Abstract Background Parkinson’s disease (PD) is a neurodegenerative characterized by intraneuronal Lewy Body (LB) aggregates composed of misfolded alpha-synuclein (α-syn). The spread α-syn follows typical pattern: starting in the olfactory bulb (OB) and gut, this pathology followed progressive invasion to posterior part brain. It unknown whether administration human mutant (hm-α-syn, mutation which occurs familial PD) into OB rats would trigger similar propagation subsequently cause...
This research is aimed at studying the effect of Angelica sinensis polysaccharide (ASP) extracted from Lixinshui prescription on cardiac disease induced by hypertension in rats. Rat models cardiovascular were established, and associated factors measured. The data showed that ASP treatment increased ejection fraction short axis shortening rate, while decreasing LV end-diastolic diameter, end-systolic volume, volume HHD downregulated expression level TGF-β1, alpha-smooth muscle actin (α-SMA),...
<title>Abstract</title> <bold>Objective:</bold> To investigate the clinical efficacy of Didang Decoction in treatment diabetic retinopathy (DR) with obstruction collaterals due to blood stasis. <bold>Methods: </bold>A total 110 patients DR whose were obstructed stasis selected and randomly divided into observation group control using a random number table, 55 each group. For 16 weeks, received standard hypoglycemic therapy while was given Decoction. Before after treatment, both groups...
Myocardial ischemia triggers an inflammatory reaction and oxidative stress that increases apoptosis of myocardiocytes. It has been evidenced tanshinone‑IIA (Tan‑IIA) protects against heart failure post‑myocardial infarction via inhibition the apoptotic pathway. The purpose present study was to investigate therapeutic effect Tan‑IIA in a rat model myocardial ischemia, explore possible mechanism established by left anterior descending coronary artery rats received treatment with either (10...
Shengmai San (SMS) is a traditional Chinese medicine (TCM) comprising three different herbal components, Panax ginseng, Ohiopogon japonicus and Fructus schisandrae has been used for treating coronary heart diseases (Bensky Barolet, 1990). It was shown that SMS effectively prevented cerebral oxidative injury in rats when it administered into the duodenum before ischemia-reperfusion. In present study, we examined whether post-ischemic administration of can ameliorate ischemia-reperfusion as...
PHAP1 (Putative HLA-DR-associated protein 1), also termed acidic leucine-rich nuclear phosphoprotein 32A (ANP32A), Phosphoprotein 32 (pp32) or phosphatase 2A inhibitor (I1PP2A), is a multifunctional aberrantly expressed in multiple types of human cancers. However, its expression pattern and clinical relevance glioma remain unknown. In this study, Western blotting immunohistochemistry analysis demonstrated was highly patients, especially those with high-grade disease. Publicly available data...
Malignant tumor has become a major threat affecting human health, and is one of the main causes death. Recent studies have shown that many traditional Chinese medicines (TCM) good anti-tumor activity, which may improve therapeutic effect routine treatment quality life with lower toxicity. However, efficacy TCM alone for tumors limited. Metal ions are essential substances maintaining normal physiological activities. This article summarized multiple mechanisms in metal involved prevention TCM.
Twelve new labdane-type diterpenoid glycosides were isolated from the stems and leaves of <italic>P. angulata</italic>.
Abstract Background Diabetic retinopathy (DR) is a common and serious microvascular complication of diabetes. Taohong Siwu decoction (THSWD), famous traditional Chinese medicine (TCM) prescription, has been proved to have good clinical effect on DR, whereas its molecular mechanism remains unclear. Our study aimed uncover the core targets signaling pathways THSWD against DR. Methods First, active ingredients were searched from Traditional Medicine Systems Pharmacology (TCMSP) Database....
Zilongjin (ZLJ) tablet, which is a traditional Chinese medicine, has been approved as new anti‐tumor drug by the State Food and Drug Administration of China; however, its anti‐cancer mechanisms remain elusive. The goal this study was to investigate underlying activities ZLJ tablet in vitro . In study, four lung cancer cell lines, A549, H446, H460 H520, were treated with 2.2 mg/mL solution for 24 h at 37 °C under 5% CO 2 RNA isolated microarray experiment using Affymetrix Human Genome U133...