A5101779180- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Infectious Aortic and Vascular Conditions
- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Cancer-related molecular mechanisms research
- Fermentation and Sensory Analysis
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Intracranial Aneurysms: Treatment and Complications
- Cardiac Arrhythmias and Treatments
- Sepsis Diagnosis and Treatment
- Moyamoya disease diagnosis and treatment
- Liver Disease and Transplantation
- Congenital Heart Disease Studies
- Cardiac electrophysiology and arrhythmias
- Circular RNAs in diseases
- Organ Transplantation Techniques and Outcomes
- Tea Polyphenols and Effects
- Cardiac Structural Anomalies and Repair
- Cardiovascular Issues in Pregnancy
- Advanced Glycation End Products research
- Intensive Care Unit Cognitive Disorders
- Cardiovascular and Diving-Related Complications
Xiangya Hospital Central South University
2014-2025
Central South University
2014-2025
Zhejiang Shuren University
2024
Zhejiang Gongshang University
2020-2023
Wenzhou Medical University
2014-2021
Zhejiang University
2017
First Affiliated Hospital of Wenzhou Medical University
2014-2015
Enhanced recovery after surgery (ERAS) pathways have not been reported in cardiac surgery. The aim of this study was to evaluate the clinical effectiveness and safety profile ERAS compared with routine care for patients undergoing valvular A randomized trial conducted between July 2015 November 2016. total 226 who underwent elective were randomly assigned pathway or (control) group. protocol consisted an evidence-based systematic optimization approach managing perioperative patients. control...
Lung cancer remains the top contributor to cancer-related mortality worldwide. Long non-coding RNAs (lncRNAs) have been reported participate in normal development and tumorigenesis. LncRNA nuclear enriched abundant transcript 1 (NEAT1) is highly expressed lung promotes cell proliferation migration. However, upstream regulatory mechanism still needs investigation. In present study, we investigated regulators mechanisms of NEAT1 expression disorders. We first examined adenocarcinoma tissues...
Cardiac fibrosis is a pathological process characterized by excess extracellular matrix (ECM) deposition and plays critical role in nearly all types of heart disease. The mechanism cardiac still unclear no effective medication treatment fibrosis. Research showed that mesenchymal stem cell (MSC) derived exosomes may play effect human amniotic fluid MSC (hAFMSC)-derived (hAFMSCExos) on has remained unclear.The hAFMSCExos were extracted using sequential centrifugation approach. effects...
Abstract Vascular calcification is a highly regulated process in cardiovascular disease (CVD) and strongly correlated with morbidity mortality, especially the adverse stage of vascular remodeling after coronary artery bypass graft surgery (CABG). However, pathogenesis calcification, particularly role endothelial‐smooth muscle cell interaction, still unclear. To test how ECs interact SMCs grafts, single‐cell analysis wild‐type mice first performed using an arterial isograft mouse model found...
Abstract OBJECTIVES Kommerell’s diverticulum presents a distinctive challenge in clinical management due to its rarity and diverse manifestations, particularly when concurrent with type B aortic dissection. However, consensus on the optimal treatment strategy has yet be established. This study our experience an open surgical approach treating associated METHODS retrospective evaluated 10 patients who underwent repair for Through median sternotomy, under cardiopulmonary bypass deep...
Abstract The observations of fully-charm tetraquark states in the LHCb, CMS and ATLAS experiments suggested existence hadronic molecules two-charmonium states, which may also imply bound three-charmonium systems. In this work, we study possible triple- η c J/ψ systems with J PC = 0 -+ 1 -- , respectively. QCD sum rules, calculate two-point correlation functions spectral up to dimension-four gluon condensate. We use iterative dispersion relation approach deal five-loop banana integrals,...
Abstract Epicardial adipose tissue (EAT) contributes to the pathophysiological process of coronary artery disease (CAD). The expression profiles long non-coding RNAs (lncRNA) in EAT patients with CAD have not been well characterized. We conducted high-throughput RNA sequencing analyze lncRNA compared without CAD. Gene Ontology (GO) and Kyoto Encyclopedia Genes Genomes (KEGG) pathway enrichment analyses were executed investigate principal functions significantly dysregulated mRNAs. confirmed...
Serum bicarbonate (HCO3-) level is strongly related to multiple cardiovascular complications. Currently, there no study evaluating the prognostic ability of serum HCO3- in intensive care unit (ICU) patients with acute aortic dissection (AAD). Hence, this was assess relationship between admission and clinical outcomes AAD.Clinical data were extracted from MIMIC-III database. Cox proportional hazards models Kaplan-Meier (KM) survival curve used evaluate association levels short- long-term...
Hyperuricemia is associated with aortic dissection and cardiovascular diseases. The implication of high serum uric acid (UA) level after acute repair remains unknown. aim this study to explore the role peri-operative UA in predicting 30-days mortality type A (AAAD) patients, who underwent surgery.This retrospectively enrolled 209 consecutive patients AAAD, surgery Xiangya Hospital from 2017 2020. Post-operative laboratory examinations were measured within 24 h surgery. Univariate analysis...
The aim of the present study was to investigate role miR-31 in Th22 differentiation coronary heart disease (CHD). frequencies peripheral blood CHD patients and controls as well CD4+ T cells were detected by flow cytometry. mRNA expression Th22-associated transcription factor aryl hydrocarbon receptor (AHR) Th22-effector cytokine interleukin (IL)-22, examined quantitative real-time PCR (qRT-PCR). protein level BTB domain CNC homolog 2 (Bach2) measured Western blotting. interaction between...
Ischemia-reperfusion injury after liver transplantation (LT) impairs graft function and affects prognosis of recipients. Isoglycyrrhizinate magnesium (Iso) is a hepatoprotective drug usually used injury. In this study, we intended to explore whether Iso alone have protective effect ischemia-reperfusion in rat model transplantation. We also aimed study could enhance the FK506 (tacrolimus) underlying mechanism.Rats LT were treated with different concentration or without, lower-dose plus Iso....
Inflammation underlies both the pathogenesis and prognosis in patients with acute aortic dissection (AAD). This study aimed to assess association of ICU admission white blood cell count (WBCc) post-discharge mortality these patients.Clinical data were extracted from MIMIC-III V1.4 database. After adjusted covariables, Cox regression analysis Kaplan-Meier survival curve performed determine relationship between WBCc on (30-day, 90-day, 1-year 5-year) AAD patients. Subgroup receiver operating...
Abstract Background Cardiac myxoma (CM) is the most common type of primary cardiac tumors. The prevalence tumors 0.0017–0.28% in various autopsy studies. clinical symptoms CM which includes embolism, intracardiac obstruction, general or constitutional manifestations and infected are largely depended on size, growing speed, location pedicle length tumor. following case reported a missed diagnostic right atrial firstly presented digestive, systemic immunologic disorder, leading to emergent...
Open thoracoabdominal aortic aneurysm (TAAA) repair is a complex and challenging operation with high incidence of serious complications, perioperative mortality morbidity. Left heart bypass (LHB) circulatory support system used to perfuse the distal aorta during TAAA operation, advantages LHB include guaranteeing perfusion, reducing use heparin, diminishing risk bleeding postoperative neurological deficits. In China, circuit for deficient, far from perfusion requirements. We designed modular...
Background Heparin-induced thrombocytopenia (HIT) in infants is a rare disorder, and the diagnosis management of HIT still remains challenging. Argatroban synthetic direct thrombin inhibitor (DTI) that widely used for treating HIT. However, little known about efficacy activated clotting time (ACT) test monitoring DTI treatment as an alternative to routinely partial thromboplastin (aPTT). Methods Between July 2013 January 2015, four were diagnosed with after surgical correction congenital...
Post-operative delirium (POD) is a common complication after aortic surgery with poor outcomes. Blood pressure may play role in the occurrence of POD. The study aimed to identify whether admission systolic blood (SBP) level intensive care unit (ICU) correlated POD acute Stanford type A dissection (AAAD) patients undergoing surgery.We conducted single-center retrospective cohort enrolling consecutive 205 surgery. Patients were divided into 3 groups: low, normal, and high SBP group. Outcomes...
This study aims to explore the core microbiota producing volatile flavor substances during fermentation of kombucha and discover potential correlations between substance. Microbial analysis based on high throughput sequencing (HTS) technology shows that bacteria Komagataeibacter, Pseudomonas, Burkholderia, Ralstonia, Halomonas, Sphingomonas fungi Dekkera, Saccharomyces cerevisiae, Botryotrichum, Monascus Pichia are dominant genera. In addition, it is found correlation fungi. During kombucha,...
Postoperative oxygenation impairment represents a common complication in patients with the acute aortic syndrome (AAS). The study aimed to explore relationship between inflammatory indicators and AAS after operation.In this study, 330 who underwent surgery were enrolled divided into 2 groups based on postoperative (non-oxygenation group group). Regression analysis was performed assess impairment. A smooth curve interaction further conducted. Stratified used according preoperative...
The optimal surgical strategy for acute type A aortic dissection (ATAAD) with coronary artery disease (CAD) remains unclear. goal of this study was to investigate the cardiovascular protective effects myocardial priority (MP) or traditional selective cerebral perfusion (SCP) in ATAAD CAD. total 214 adults were analyzed retrospectively, which 80 underwent MP intraoperatively. Seventy-nine pairs propensity-score-matched and divided into SCP groups. follow-up period ranged from 6 36 months....