An in vivo study to measure rat spinal cord blood flow real-time at the site of compression using a newly developed device.To evaluate change thoracic by force and clarify association between recovery motor deficiency after injury.Until now, no measurement has been conducted. In addition, it not clearly determined whether is related function injury.Our system was combination noncontact type laser Doppler device. The exposed 11th vertebra continuously measured before, during, compression....

A retrospective cohort study.To investigate the risk factors for postoperative delirium after spine surgery, excluding older age, which has already been established as a strong factor.More than 30 have reported making it challenging to identify should be prioritized. We hypothesized that could not prioritized date because factor of age is very and influenced other factors. To eliminate influence we performed an age-matched group comparison analysis investigation factors.This study involved...

Adenosine is an endogenous neuromodulator in both the peripheral and central nervous systems. inhibits pain signals by hyperpolarizing neuronal membrane. To clarify effects of adenosine on signals, we tested intrathecal injection two neuropathic pains (spinal cord compression chronic constriction sciatic nerve) postoperative (plantar incision). In all three kinds models, significant shortening withdrawal latencies to thermal stimulation were detected from 24 h 1 week after surgery....

Study Design. Retrospective case-control study. Objective. To investigate the prevalence and characteristics of diffuse idiopathic skeletal hyperostosis (DISH) in vertebral fracture patients admitted to our hospital. Summary Background Data. Although is generally treated conservatively with rest use a corset, surgery rigid internal fixation recommended for fractures DISH. Thus, treatment strategies differ according presence or absence However, only few studies have investigated DISH...

Several studies have reported the prognostic factors for soft tissue sarcoma. Although serum lactate dehydrogenase (LDH) levels are associated with poor prognosis in several types of cancer, their role sarcomas remains unclear. Therefore, present study evaluated association between LDH and clinical characteristics A total 103 patients diagnosed primary sarcoma 2003 2019 were retrospectively examined, at first visit analysed. In high-grade sarcoma, survival characteristics, including...

Elucidation of the process degeneration injured axons is important for development therapeutic modules treatment spinal cord injuries. The aim this study was to establish a method time-lapse observation in living animals after contusion injury. YFP (yellow fluorescent protein)-H transgenic mice, which we used study, express fluorescence their nerve fibers. Contusion damage at 11th vertebra performed by IH (Infinite Horizon) impactor, applied pressure 50 kdyn. damaged cords were re-exposed...

The effect of intracellular cyclic guanosine monophosphate (GMP) increase on neuronal damage was tested using a newly developed nitric oxide-related injury model cultured spinal cord neurons.Neuronal after 24-hour-exposure to sodium nitroprusside (SNP), oxide (NO) donor, evaluated by measuring the activity released lactate dehydrogenase from injured neurons.Oxygen radical scavengers had protective effect, indicating that damage, elicited 10 μM SNP, largely due peroxynitrite formation....

Despite the availability of several modalities treatment, including surgery, pharmacological agents, and nerve blocks, neuropathic pain is often unresponsive sometimes progresses to intractable chronic pain. Although exercise therapy a candidate for treatment pain, mechanism underlying its efficacy has not been elucidated. To clarify molecular relief induced by exercise, we measured Rnf34 Pacap mRNA levels in spinal cord dorsal horn SNL rats, model rats exhibited stable mechanical...

Background: We report 8 years of follow-up after decompression to treat cervical myelopathy in a patient with Coffin–Lowry syndrome (CLS). CLS is rare X-linked semidominant associated growth and psychomotor retardation, general hypotonia, skeletal abnormalities. In this patient, the spinal cord was compressed by calcium pyrophosphate crystal deposition yellow ligament (YL). To date, only 1 has described clinical features surgery for calcified YL CLS. Methods: A 15-year-old male tetraplegia...

✓ Periosteal chondromas located in the spine are rare. The authors document a case of periosteal chondroma lumbar spinal canal 77-year-old man. patient had severe pain his right leg and used wheelchair because weakness both legs. Magnetic resonance imaging revealed round tumor that was hypo- or isointense on T1-weighted images uniformly hyperintense T2-weighted images. Administration gadolinium-diethylenetriamine pentaacetic acid resulted margin enhancement During operation, 1.5 cm diameter...

Background: It has been documented that diffuse idiopathic skeletal hyperostosis (DISH) exhibits a higher prevalence among elderly, male, and obese individuals. Additionally, diabetes mellitus other comorbidities are more frequently observed in this patient population. However, there is lack of reports exploring the correlation between extent ossification these demographic clinical characteristics. Objective: To examine severity anterior longitudinal ligament patients with DISH. Materials...