A5084906958- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Optical Coherence Tomography Applications
- Cardiovascular Function and Risk Factors
- Peripheral Artery Disease Management
- Cardiovascular Disease and Adiposity
- Atherosclerosis and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Lipoproteins and Cardiovascular Health
- Cardiac Fibrosis and Remodeling
- Immune cells in cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Heart Rate Variability and Autonomic Control
- Aortic aneurysm repair treatments
- Hormonal Regulation and Hypertension
- Angiogenesis and VEGF in Cancer
- Systemic Sclerosis and Related Diseases
- Protease and Inhibitor Mechanisms
- Cardiac pacing and defibrillation studies
- Aortic Thrombus and Embolism
- Diabetes Treatment and Management
- Photoacoustic and Ultrasonic Imaging
Hidaka Hospital
2016-2020
Wakayama Medical University
2009-2018
Deutsches Herzzentrum München
2017
St. Antonius Ziekenhuis
2017
Technical University of Munich
2017
KU Leuven
2017
Glenfield Hospital
2017
Ospedale Papa Giovanni XXIII
2013-2016
Cardiac Society of Australia and New Zealand
2012
Wakayama University
2008-2010
Stent thrombosis (ST) is a serious complication following coronary stenting. Intravascular optical coherence tomography (OCT) may provide insights into mechanistic processes leading to ST. We performed prospective, multicenter study evaluate OCT findings in patients with ST.Consecutive presenting ST were prospectively enrolled registry by using centralized telephone registration system. After angiographic confirmation of ST, imaging the culprit vessel was frequency domain OCT. Clinical data...
Although some recent guidelines recommend an early invasive strategy for non-ST-segment elevation acute coronary syndrome (NSTEACS), several studies have failed to identify any benefit very intervention NSTEACS. The no-reflow phenomenon may inhibit the expected from recanalization NSTEACS subjects. aim of this study was investigate whether optical coherence tomography (OCT) could predict in patients with NSTEACS.This comprised 83 consecutive who underwent OCT and successful emergent primary...
Intracoronary optical coherence tomography (OCT) is a high-resolution imaging modality used for evaluation of coronary lesion morphology. However, current time-domain OCT (TD-OCT) have number limitations with regard to both procedural usage and safety in the clinical setting. The next-generation frequency-domain (FD-OCT), which has much faster frame rate pullback speed than TD-OCT, expected overcome these limitations. aim this study was evaluate feasibility usability next generation FD-OCT...
Background: Although an intracoronary frequency-domain optical coherence tomography (FD-OCT) system overcomes several limitations of the time-domain OCT (TD-OCT) system, former requires injection contrast media for image acquisition. The increased total amount FD-OCT acquisition may lead to impairment renal function. safety and usefulness non-occlusion method with low-molecular-weight dextran L (LMD-L) via a guiding catheter TD-OCT have been reported previously. aim present study was compare...
Background: For the identification of functionally significant coronary artery disease, there have not been any dedicated optical coherence tomography (OCT) studies reported previously, although OCT can clearly detect vessel lumina at higher resolution than intravascular ultrasound (IVUS). Methods and Results: fractional flow reserve (FFR) measurements were performed in 62 intermediate lesions 59 patients. FFR was calculated as ratio distal pressure divided by proximal during maximal...
Background: Recent studies suggest that fractalkine (FKN or CX3CL1) and its cognate receptor, CX3CR1, play a role in atherogenesis, so the relationship between coronary plaque rupture, as observed by preintervention optical coherence tomography, plasma levels of FKN CX3CR1 was investigated this study. Methods Results: The study population consisted 46 patients with unstable angina pectoris (UAP), 30 stable pectoris, 25 healthy controls. UAP underwent tomography study, which revealed number...
Background— The frequency of papillary muscle infarction (PapMI) without rupture has not been fully investigated in vivo. Furthermore, the relationship between dysfunction and mitral regurgitation (MR) controversial patients with ST-segment elevation myocardial infarction. Therefore, aim this study was to assess clinical characteristics PapMI using late gadolinium-enhanced magnetic resonance imaging (MRI) Methods Results— One hundred eighteen primary percutaneous coronary intervention...
Background— Plaque contents can cause microvascular impairment, which is an important determinant of clinical outcomes in patients with acute coronary syndrome (ACS). We hypothesized that percutaneous intervention (PCI) for thin-cap fibroatheroma (TCFA) could easily disrupt the fibrous cap and expose plaque to flow, possibly resulting obstruction (MVO). The purpose this study was investigate whether TCFA associated MVO after PCI ACS. Methods Results— enrolled 115 ACS who were successfully...
AimsThe importance of oxidized low-density lipoprotein (oxLDL) has been implicated in the process plaque rupture. However, few previous studies demonstrated relationship between morphology and oxLDL. We evaluated coronary vulnerability assessed by optical coherence tomography (OCT) circulating malondialdehyde-modified (MDA-LDL).
Background: Circulating monocytes can be divided into 2 subsets typically identified by the expression of CD14 and CD16. Although previous studies have shown that circulating contribute to progression coronary atherosclerotic lesions, relationship between severity artery disease (CAD) distinct monocyte has not previously been evaluated. We investigated CAD assessed angiography (CAG) in patients with stable angina pectoris (SAP). Methods Results: enrolled 125 who underwent diagnostic CAG....
Virtual histology intravascular ultrasound (VH-IVUS) allows detailed assessment of plaque composition in the clinical setting. Optical coherence tomography (OCT) has been developed as a high-resolution imaging method, which might be promising technique to identify thin-cap fibroatheroma (TCFA) vivo. The purpose present study was evaluate diagnostic accuracy VH-IVUS TCFA determined by OCT.We examined 96 target lesions patients with stable angina pectoris using and OCT. derived defined focal...