A5102879586- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Optical Coherence Tomography Applications
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Cardiovascular Disease and Adiposity
- Atherosclerosis and Cardiovascular Diseases
- Aortic aneurysm repair treatments
- Cardiac pacing and defibrillation studies
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Structural Anomalies and Repair
- Cardiac Arrhythmias and Treatments
- Lipoproteins and Cardiovascular Health
- Cardiac Fibrosis and Remodeling
- Immune cells in cancer
- Antiplatelet Therapy and Cardiovascular Diseases
- Heart Failure Treatment and Management
- Systemic Lupus Erythematosus Research
- Inflammatory Biomarkers in Disease Prognosis
- Photoacoustic and Ultrasonic Imaging
- Nitric Oxide and Endothelin Effects
- Aortic Thrombus and Embolism
Wakayama Medical University
2016-2025
MedStar Washington Hospital Center
2013-2014
American Heart Association
2014
Cardiac Society of Australia and New Zealand
2012
Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences
2009
Kawasaki Medical School
2008
Wakayama University
2007
Background— Plaque rupture and secondary thrombus formation play key roles in the onset of acute coronary syndrome (ACS). One pathological study suggested that morphologies plaque differed between rest-onset exertion-triggered men who experienced sudden death. The aim present was to use optical coherence tomography investigate relationship patients with ACS morphology a ruptured patient’s activity at ACS. Methods Results— population drawn from 43 consecutive (with or without ST-segment...
Intracoronary optical coherence tomography (OCT) is a high-resolution imaging modality used for evaluation of coronary lesion morphology. However, current time-domain OCT (TD-OCT) have number limitations with regard to both procedural usage and safety in the clinical setting. The next-generation frequency-domain (FD-OCT), which has much faster frame rate pullback speed than TD-OCT, expected overcome these limitations. aim this study was evaluate feasibility usability next generation FD-OCT...
We investigated whether aliskiren, a direct renin inhibitor, improves NO bioavailability and protects against spontaneous atherosclerotic changes. also examined the effects of cotreatment with aliskiren valsartan, an angiotensin II receptor blocker, on above-mentioned outcomes. Watanabe heritable hyperlipidemic rabbits were treated vehicle (control), or plus valsartan for 8 weeks. Then, acetylcholine-induced production was measured as surrogate index endothelium protective function, both...
Background: Although an intracoronary frequency-domain optical coherence tomography (FD-OCT) system overcomes several limitations of the time-domain OCT (TD-OCT) system, former requires injection contrast media for image acquisition. The increased total amount FD-OCT acquisition may lead to impairment renal function. safety and usefulness non-occlusion method with low-molecular-weight dextran L (LMD-L) via a guiding catheter TD-OCT have been reported previously. aim present study was compare...
Background: Recent studies suggest that fractalkine (FKN or CX3CL1) and its cognate receptor, CX3CR1, play a role in atherogenesis, so the relationship between coronary plaque rupture, as observed by preintervention optical coherence tomography, plasma levels of FKN CX3CR1 was investigated this study. Methods Results: The study population consisted 46 patients with unstable angina pectoris (UAP), 30 stable pectoris, 25 healthy controls. UAP underwent tomography study, which revealed number...
Background— Clinical presentation of bare metal stent in-stent restenosis (ISR) in patients undergoing target lesion revascularization is well characterized and negatively affects on outcomes, whereas the outcomes first- second-generation drug-eluting stents (DESs) remains under-reported. Methods Results— The study included 909 (1077 ISR lesions) distributed as follows: (n=388), first-generation DES (n=425), (n=96), categorized into acute coronary syndrome (ACS) or non-ACS mode at time first...
Background Because optical coherence tomography (OCT) requires balloon-occlusion to overcome image attenuation by blood, the present study investigated safety and usefulness of a new non-occlusive technique. Methods Results The 40 angina patients were assigned continuous-flushing method or group. was superior for observing proximal lesions compared with (94% vs 55%, p=0.01). There no differences between groups in visible length quality. major complications during OCT. Conclusions is safe...
Background: Thin-capped fibroatheroma (TCFA) is a recognized precursor lesion for acute coronary syndrome (ACS). Positive remodeling (PR) the predominant pattern of arterial in patients with ACS. The aim this study was to evaluate relationship between remodeling, fibrous cap thickness and high-sensitivity C-reactive protein (hs-CRP) concentration Methods Results: 47 consecutive ACS were enrolled study. Arterial culprit plaque assessed by intravascular ultrasound, measured optical coherence...