Bruce K. Young

ORCID: 0000-0001-8518-9436
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About
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Research Areas
  • Pregnancy and preeclampsia studies
  • Neonatal Respiratory Health Research
  • Prenatal Screening and Diagnostics
  • Assisted Reproductive Technology and Twin Pregnancy
  • Preterm Birth and Chorioamnionitis
  • Neonatal and fetal brain pathology
  • Mesenchymal stem cell research
  • Birth, Development, and Health
  • Maternal and Perinatal Health Interventions
  • Tissue Engineering and Regenerative Medicine
  • Reproductive System and Pregnancy
  • Cardiovascular Issues in Pregnancy
  • Maternal and fetal healthcare
  • Fetal and Pediatric Neurological Disorders
  • Renal function and acid-base balance
  • Pluripotent Stem Cells Research
  • Pregnancy-related medical research
  • Gastroesophageal reflux and treatments
  • Congenital Diaphragmatic Hernia Studies
  • Congenital Anomalies and Fetal Surgery
  • Cardiac, Anesthesia and Surgical Outcomes
  • Metabolism and Genetic Disorders
  • Pediatric Urology and Nephrology Studies
  • Nitric Oxide and Endothelin Effects
  • Pregnancy and Medication Impact

NYU Langone Health
2013-2024

New York University
2007-2023

Creative Commons
2020

Columbia University Irving Medical Center
1985-2012

University Medical Center
1978-2000

University Medical Center Utrecht
2000

Bellevue Hospital Center
1976-1995

Memorial Medical Center
1991

Society for Maternal-Fetal Medicine
1980

Institute of Rural Management Anand
1979

Objective: Nitric oxide, a potent vasodilator released by endothelial cells, inhibits platelet aggregation and adhesion to vascular surfaces. Because cell damage is considered pivotal in the pathogenesis of preeclampsia, this study was initiated determine whether nitric oxide production decreased patients with preeclampsia. Study Design: Twenty-six preeclampsia (as defined blood pressure ≥ 140 mm Hg systolic or 90 diastolic plus proteinuria, 300 mg per 24 hours 2 + dipstick, both occurring...

10.1016/s0002-9378(94)70064-8 article EN cc-by-nc-nd American Journal of Obstetrics and Gynecology 1994-10-01

Abstract Objective. To assess the activity of systemic lupus erythematosus (SLE) during pregnancy and to distinguish it from preeclampsia. Methods. We prospectively measured complement activation products Ba, Bb, SC5b—9, C4d, as well conventional determinants C3, C4, CH50, in 14 patients with SLE 10 women Results. Four were considered have disease flares, 3 occurring second trimester 1 postpartum. In these patients, significant abnormalities CH50 noted. contrast, measures C4d did not between...

10.1002/art.1780350109 article EN Arthritis & Rheumatism 1992-01-01

10.1016/0002-9378(80)91008-x article EN American Journal of Obstetrics and Gynecology 1980-03-01

Abstract Hydrocephalic women with cerebrospinal fluid shunts are now surviving to reproductive age. Twenty-one pregnancies in 18 patients shunts, including 11 from the present series and 10 previous series, were analyzed for neurological, obstetrical, perinatal outcome. Fourteen had preexisting 4 onset of symptomatic hydrocephalus placement during pregnancy. Neurological complications occurred 13 17 (76%) symptoms increased intracranial pressure (ICP) (59%) pregnancies, exacerbation seizure...

10.1227/00006123-199112000-00004 article EN Neurosurgery 1991-12-01

This paper proposes a novel approach for detecting fetal heart rate (FHR) using seismo-cardiogram (SCG) and gyro-cardiogram (GCG) recordings collected from abdominal inertial sensors. A proof-of-concept setup with commercially available sensor nodes is prepared. The FHR components are extracted the fused cepstrum of all feasibility proposed method evaluated experiments on ten pregnant women under supine, seated, standing positions. results compared simultaneously-collected cardiotocography...

10.1109/jsen.2019.2930886 article EN publisher-specific-oa IEEE Sensors Journal 2019-07-24

10.1016/s0002-9378(16)32284-0 article EN American Journal of Obstetrics and Gynecology 1982-01-01

A method is described for the assay of estriol conjugates in amniotic fluid. Tritiated estriol-3 sulfate (E3-3S), estriol-16 glucosiduronate (E3-16G), (E3-3G) and sulfate-16 (E3-3S-16G) are added to After removal proteins, separated on a Celite partition column. Each conjugate hydrolyzed with Glusulase E3 purified by chromatography Sephadex LH-20. Assay fluorescence. The was applied 7 samples obtained from midpregnancy term pregnancy. total 0.84 9.3 μg/ml former 74 311 μg/100 ml latter. most...

10.1210/jcem-35-2-208 article EN The Journal of Clinical Endocrinology & Metabolism 1972-08-01

In Brief Objective To determine whether the degree of cervical lengthening after cerclage and serial follow-up measurements length are predictive pregnancy outcome. Methods Eighty women whose primary physician determined that a prophylactic (n = 50) or urgent 30) was indicated had transvaginal ultrasonographic evaluation before cerclage. Thereafter, most three additional ultrasound examinations until 32 weeks' gestation. At each examination, mean calculated. Statistical analyses were done by...

10.1097/00006250-200009000-00006 article EN Obstetrics and Gynecology 2000-09-01

This study attempts to determine the major source of lactate in normal and depressed human fetus, order assess applicability fetal blood measurement for evaluation stress during labor. We obtained umbilical arterial venous samples at delivery 132 liveborn infants, together with simultaneous maternal radial samples. All were analyzed immediately pH, gases, lactate. In vigorous newborns (1-minute Apgar score greater than or equal 7), levels lowest elective cesarean section done before onset...

10.1515/jpme.1984.12.4.211 article EN Journal of Perinatal Medicine 1984-01-01

We report only the 3 rd case of closure amniorrhexis following genetic amniocentesis. Our techinque is first to use endoscopic visualization rupture site and apply maternal platelets fibrinogen/thrombin (Hemaseel ® Haemacure Corp Sarasota Fl). The patient underwent repair at 20.6 weeks, 26 days after spontaneous membranes post-amniocentesis. At time procedure amniotic fluid index was 1 cm. Patient delivered 32.3 weeks secondary complications diabetes severe preeclampsia. neonate had APGARS 7...

10.1515/jpm.2000.042 article EN Journal of Perinatal Medicine 2000-01-11

To describe a new technique for wound closure after endoscopic intrauterine procedures which prevents amniotic fluid leakage the procedure.This is an observational study reviews under IRB-approved protocol. The rationale this was increasing frequency of procedures. most common complication these persistent from puncture sites, can result in preterm labor and delivery. Thus, carry high morbidity rate that may overcome benefit intervention. We have employed technique, has successfully...

10.1159/000076715 article EN Fetal Diagnosis and Therapy 2004-01-01

10.1016/s0002-9378(84)80105-2 article EN American Journal of Obstetrics and Gynecology 1984-09-01
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