A5066796010- Textile materials and evaluations
- HIV/AIDS drug development and treatment
- Methane Hydrates and Related Phenomena
- Biochemical and Molecular Research
- Carbohydrate Chemistry and Synthesis
- Spacecraft and Cryogenic Technologies
- Thermoregulation and physiological responses
- DNA and Nucleic Acid Chemistry
- Protein Structure and Dynamics
- RNA and protein synthesis mechanisms
- CO2 Sequestration and Geologic Interactions
- Consumer Perception and Purchasing Behavior
- Dyeing and Modifying Textile Fibers
- Pharmacological Effects of Natural Compounds
- Advanced biosensing and bioanalysis techniques
- Inorganic Fluorides and Related Compounds
- Crystallization and Solubility Studies
- Bioactive Compounds and Antitumor Agents
- Color perception and design
- Synthesis and Characterization of Heterocyclic Compounds
- Cell death mechanisms and regulation
- Ginseng Biological Effects and Applications
- Bone health and treatments
- Click Chemistry and Applications
- Bone Metabolism and Diseases
Chosun University
2015-2024
Sungkyunkwan University
2024
Chonnam National University
2024
Research Institute of Industrial Science and Technology
2023-2024
Yeungnam University
2012-2022
Korea Advanced Institute of Science and Technology
2005-2021
Seoul National University
2017-2021
Korea Institute of Materials Science
2020
Korea Research Institute of Chemical Technology
2018-2019
Yonsei University
2006-2018
In this study, the feasibility of gas hydrate-based greenhouse (CHF3) separation was investigated with a primary focus on thermodynamic, structural, and cage-filling characteristics CHF3 + N2 hydrates. The three-phase (hydrate (H)–liquid water (LW)–vapor (V)) equilibria (10%, 20%, 40%, 60%, 80%) systems provided thermodynamic stability conditions Powder X-ray diffraction revealed that structure hydrates identified as sI (Pm3n) for all concentration ranges considered in study. A...
The anticancer therapeutic effects of usnic acid (UA), a lichen secondary metabolite, have been demonstrated in vitro and vivo. However, the mechanism underlying effect UA remains to be clarified. In this study, target protein was identified using UA-linker-Affi-Gel molecule, which showed that binds 14-3-3 protein. 14-3-3, causing degradation proteasomal autophagosomal proteins. interaction with isoforms modulated cell invasion, cycle progression, aerobic glycolysis, mitochondrial...
We proposed a simple van der Waals backbone correction (O2' and OP) to the AMBER ff12 force field in conjunction with OPC water via an unequal Lorentz-Berthelot combination rule. As tested on four different tetranuceotides such as r(GACC), r(CCCC), r(AAAA), r(CAAU), this new correctly captured each native fold largest population. For RNA tetraloop (UUCG) tested, stability of its is substantially improved.
Houghton (HG) base pairing plays a central role in the DNA binding of proteins and small ligands. Probing detailed transition mechanism from Watson–Crick (WC) to HG pair (bp) formation duplex DNAs is fundamental importance terms revealing intrinsic functions double helical beyond their sequence determined functions. We investigated free energy landscape B-DNA with an adenosine–thymine (A–T) rich probe its conformational pathways WC pairing. The was computed state-of-art two-dimensional...
Investigating the genetic and environmental causes of variation in genome-wide average DNA methylation (GWAM), a global measure from HumanMethylation450 array, might give better understanding influences on methylation.We measured GWAM for 2299 individuals aged 0 to 90 years seven twin and/or family studies. We estimated familial correlations, modelled correlations with cohabitation history fitted variance components models GWAM.The correlation pairs was ∼0.8 at birth, decreased age during...
Licochalcone D (LCD), a flavonoid isolated from Chinese medicinal plant Glycyrrhiza inflata, has variety of pharmacological activities. However, the anti-cancer effects LCD on non-small cell lung cancer (NSCLC) have not been investigated yet. The amplification MET (hepatocyte growth factor receptor) compensates for inhibition epidermal receptor (EGFR) activity due to tyrosine kinase inhibitor (TKI), leading TKI resistance. Therefore, EGFR and can be attractive targets cancer. We...
In this study, the effects of number and position fabrics treated with phase-change materials (PCMs) on thermo-regulating properties in four-layer garments were investigated. Nanosilver-coated nonadecane was employed as a PCM coated onto cotton for study. The heating cooling evaluated by measuring temperature changes air layers microclimate within clothing using Human–Clothing–Environment simulator. Results showed that increased incorporation PCM-treated garment led to effects. cases which...
An electrospun nanofiber web membrane is thinner, lighter and more moisture permeable than other types of membrane, but it has low waterproof poor abrasion resistance. To improve its waterproofness resistance a waterborne polyurethane coating been applied the change in water vapor permeability waterproofness, examined, together with effect on fabric structure. The hydrophilicity resin these were properties was also assessed. Taffeta taslan used as base fabrics, resins maintained at 10, 15,...
Dysregulation of the anti-apoptotic protein, cellular FLICE-like inhibitory protein (c-FLIP), has been associated with tumorigenesis and chemoresistance in various human cancers. Therefore, c-FLIP is an excellent target for therapeutic intervention. MicroRNAs (miRNAs) are small non-coding RNAs that involved tumorigenesis, tumor suppression, resistance or sensitivity to anti-cancer drugs. However, whether miRNAs can suppress c-FLIPL expression cancer cells unclear. The aim this study was...
As one of the perovskite families, potassium sodium niobates (K1–xNax)NbO3 (KNN) have been gaining tremendous attention due to their various functional properties which can be largely determined by crystallographic phase and composition. However, a selective evolution different phases for KNN with controlled composition difficult achieve, especially in solution chemical synthesis because its strong tendency stabilize into orthorhombic at conventional synthetic temperature. We herein...
Abstract This study was performed to estimate the exchange of air (ventilation) and temperature distribution in cylinder that simulated human body. Simulation simplified body wearing running wear jacket with slits. Slits were positioned at shoulder, mid-back lower-back. For jacket, non-air permeable material assumed eliminate effect porosity fabrics. Airflow microclimate analyzed using computational fluid dynamics (CFD). The results showed tended rise drift towards Air flown out through...
Abstract Oral cancer is of an aggressive malignancy that arises on oral cavity and lip, 90% cancers histologically originated in the squamous cells. Licochalcone (LC)C has been known as natural phenolic chalconoid substances, its origin root Glycyrrhiza glabra or inflata . LCC inhibited cell carcinoma (OSCC) viability, mitochondrial function, anchorage‐independent growth a dose‐dependent manner. To investigate ability to target Janus kinase 2 (JAK2), we performed pull‐down binding assay,...
Deoxypodophyllotoxin (DPT) is a cyclolignan compound that exerts anti-cancer effects against various types of cancers. DPT induces apoptosis and inhibits the growth breast, brain, prostate, gastric, lung, cervical tumors. In this study, we sought to determine effect on cell proliferation, apoptosis, motility, tumorigenesis three colorectal cancer (CRC) lines: HT29, DLD1, Caco2. inhibited proliferation these cells. Specifically, compound-induced mitotic arrest in CRC cells by destabilizing...