A5041919373- Salivary Gland Tumors Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Reproductive System and Pregnancy
- Oral and Maxillofacial Pathology
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Toxin Mechanisms and Immunotoxins
- Gestational Diabetes Research and Management
- Ear and Head Tumors
- IL-33, ST2, and ILC Pathways
- Cell death mechanisms and regulation
- Cancer-related Molecular Pathways
- Oral Health Pathology and Treatment
- Microtubule and mitosis dynamics
- Ocular Infections and Treatments
- Musculoskeletal pain and rehabilitation
- Diverse Scientific Research Studies
- Myasthenia Gravis and Thymoma
- Cancer and Skin Lesions
- Ubiquitin and proteasome pathways
- Economic and Industrial Development
- Electromagnetic Fields and Biological Effects
- Temporomandibular Joint Disorders
- Periodontal Regeneration and Treatments
- Heat shock proteins research
Shiraz University of Medical Sciences
2014-2025
Shiraz University
2014
Aurora kinase A (AurkA) plays a vital role in mitosis and is therefore critical tumors development progression. There are few studies on AurkA expression salivary gland tumors. The aim of the present study was to evaluate pattern most common benign malignant by immunohistochemistry. In this retrospective cross-sectional study, 68 cases including 25 pleomorphic adenomas (PAs), 21 adenoid cystic carcinomas (ADCa), 15 mucoepidermoid (MEC), 7 normal glands (NSG) were enrolled from archive...
Nicotine is a major component of tobacco plants and responsible for the development reproductive problems in smokers. has been recognized to result oxidative stress by inducing generation reactive oxygen species (ROS) some parts female system, but effect nicotine on endometrium that plays an important role biology stays unexplored. The aim this work was clarify direct effects administration antioxidant defense system lipid peroxidation human endometrial cells. Human stromal primary cells...
Background: BIRC6, regarded as the pivotal member of inhibitor apoptosis (IAP) family, has been linked to development different types cancer in humans. The objective this study was examine expression BIRC6 various oral conditions, including OLP with dysplasia (OLPD), hyperkeratosis (HK), OLP, epithelial (ED), and squamous cell carcinoma (OSCC), investigate its potential involvement OSCC pathogenesis malignant transformation which is known a precancerous condition. Methods: In retrospective...
Background: Paxillin is a cytoskeletal protein involved in the pathogenesis of several types cancers. However, roles paxillin epithelial dysplasia (ED), oral squamous cell carcinoma (OSCC), lichen planus with (OLPD), hyperkeratosis (HK), and (OLP) have remained unnoticed literature. This study aimed to evaluate its attainable functions malignant transformation potentially epithelium benign lesions. Methods: In this retrospective cross-sectional study, expression was investigated 99 tissue...
Among leading causes of the ischemic stroke pathogenesis, oxidative stress strongly declines rate stem cell engraftment at injury site, and disables cell-based therapy as a key treatment for ischemia stroke. To overcome this therapeutic limitation, preconditioning has been represented possible approach to augment adaptation viability cells stress. Here, we illustrated protective impacts valproic acid (VPA) and/or rapamycin (RAPA) unto oxygen glucose serum deprivation (OGSD)-stimulated damage...
Endometriosis is a common gynecological disease in which oxidative stress potential factor. Caffeine and caffeic acid are present various foods beverages with anti-oxidant, anti-inflammatory, anti-carcinogenic properties. In this study, we aimed to investigate the ameliorative effects of caffeine, acid, caffeine+caffeic treatments on ectopic endometrial cells taken from patients eutopic ones women without endometriosis.In experimental were obtained biopsies free (n=10) endometriosis who...
This study was designed to assess oxidative damage and cell apoptosis in the uterus of rats with streptozotocin (STZ)-induced diabetes. The role vitamin E (VE) and/or folic acid (FA) protection from such also evaluated. treatments were performed for 4 weeks on six groups rats: 1) normal control 2) diabetic 3) receiving olive oil as a vehicle (without VE) 4) treated VE (200 mg/kg) 5) FA (25 6) VE+FA 25 mg/kg, respectively). We measured malondialdehyde level (MDA), glutathione content (GSH)...
Objective: Twist is an important transcription factor that induces epithelial-mesenchymal transition and therefore plays role in tumor progression.There are a few studies on expression salivary gland carcinomas.The aim of this study was to evaluate compare the most common benign malignant tumors determine whether its correlated with any characteristics.Material Method: retrospective cross-sectional study, 45 cases including 11 normal gland, 12 pleomorphic adenomas, adenoid cystic carcinomas...
Job burnout is a stress-related phenomenon that significant threat to the health and performance of organizations employees. Interventions ameliorate potentials for have been limited by lack comprehensive tool considers work system stressors. Thus, aim this study was develop questionnaire predicting job based on macroergonomics approach. The setting petrochemical company in South Iran. In qualitative phase sequential exploratory mixed methods research, 971 meaning codes were extracted from...
Different factors are involved in the incidence, etiology, metastasis, diagnosis, and treatment of oral squamous cell carcinoma, including apoptosis inhibitor proteins. Baculoviral IAP repeat containing protein 6 (BIRC6) is one proteins contributing to cancer cells' survival many types with diagnostic importance. This study aimed at assessing serum level BIRC6 carcinoma.In this retrospective cross-sectional study, 60 samples were collected from 45 male 15 female patients a mean age 61 years...
BACKGROUND: Interleukin-33 (IL-33) has been recently discovered as an influential factor in the process of tumor immunity, and is presented cancer pathogenesis. OBJECTIVE: This study aimed to determine serum levels IL-33 patients with benign malignant Salivary gland tumors (SGTs). METHODS: descriptive cross-sectional was performed on 47 samples SGTs including 18 mucoepidermoid carcinoma (MEC), 8 adenoid cystic (ADCC), 21 mixed (MMT), 14 pleomorphic adenoma (PA). A control group considered...
Objective: Midkine is a heparin-binding growth factor whose expression increased in most tumors, namely ameloblastomas.This study aimed to compare different odontogenic lesions. Material and Method:This analytical cross-sectional was performed on 52 definitely diagnosed lesions including 15 dentigerous cysts, 13 keratocysts, 17 unicystic 5 multicystic ameloblastomas archived from 1997 2015.Midkine examined tissue samples through immunohistochemistry.The nonparametric Kruskal-Wallis...
The castability of nonprecious gold color alloy using torch/ centrifugal and induction/vacuum-pressure casting techniques has not been studied yet.This study was conducted to compare the nickel chromium, cobalt-chromium torch/centrifugal induction/ vacuum-pressure techniques.In this in vitro study, a total number 54 identical acrylic wax meshes were prepared divided into 6 different groups 9 each. Group 1: nickel-chromium alloy, which casted with induction technique. 2: 3: 4: 5: 6: Then...
The present study is the first attempt made to investigate effects of diabetes on expression and promoter DNA methylation TGF-β1, ESR-1, CDH-1 genes also folic acid (FA) vitamin E (Vit E) supplementations improving mellitus. STZ-induced diabetic rats were treated with Vit (200 mg/kg/day) FA (25 for 8 weeks in uterus analysed. Data indicated that increases TGFβ-1 ESR-1 decreases rats. improved negative by decreasing increasing In conclusion, these findings emphasise could improve caused...
Background: Bioactivation of nitroglycerin (NTG) leads to the production reactive oxygen species and nitrogen species. The aim this study was investigate effects NTG treatment on redox homeostasis in rat uterus around the time implantation number pups. M aterials Methods: rats long-term test groups were treated subcutaneously with (15mg/kg BW) normal saline (1ml/kg B) control for 4 weeks. Afterwards, they mated divided into four groups. Two until 5 days after mating. Thereafter, sacrificed...
The epithelial-to-mesenchymal transition (EMT) is a unique process resulting in enhanced cell motility, invasiveness, and metastasis cancer. EMT regulated by several transcription factors, including Snail Slug, which exert crucial roles during cancer progression. We have studied the effects of Docetaxel as first-line chemotherapy agent for prostate cancer, Telmisartan an anti-hypertensive drug on expression level Slug. In addition, Docetaxel, their combination proliferation were...