A5103165302- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Carbon Nanotubes in Composites
- Conducting polymers and applications
- Gas Sensing Nanomaterials and Sensors
- Graphene research and applications
- Advanced Sensor and Energy Harvesting Materials
- MicroRNA in disease regulation
- Analytical Chemistry and Sensors
- Polymer composites and self-healing
- Silicone and Siloxane Chemistry
- Nanomaterials for catalytic reactions
- Organic Electronics and Photovoltaics
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Minerals Flotation and Separation Techniques
- Advanced Chemical Sensor Technologies
- Analytical chemistry methods development
- RNA modifications and cancer
- Copper-based nanomaterials and applications
- Surface Modification and Superhydrophobicity
- Electrocatalysts for Energy Conversion
- Synthesis and properties of polymers
- Extraction and Separation Processes
- Immune Cell Function and Interaction
Sun Yat-sen University
2025
Dalian Ocean University
2025
Nanchang Normal University
2025
Southeast University
2025
Ministry of Agriculture and Rural Affairs
2025
Sun Yat-sen Memorial Hospital
2025
University of Jinan
2024
Xiangya Hospital Central South University
2010-2024
Central South University
2010-2024
Nantong University
2024
One key to malignant progression of pancreatic cancer (PC) is the acquired ability tumour cells escape immune-mediated lysis. Hypoxic microenvironment plays a causal role in PC metastasis. According previous studies, hypoxia could induce upregulation HIF1A, ADAM10 and sMICA, leading decreased NKG2D NK from immune surveillance cell-mediated In present study, derived high-HIF1A expression patients, levels internalization MICA/B were obviously higher than those low-HIF1A group; dramatically...
A vinylogous tetrathiafulvalene (TTFV) monomer was prepared and copolymerized with fluorene to give a conformationally switchable conjugated copolymer. This copolymer shown undergo conformational change upon protonation trifluoroacetic acid (TFA). When mixed single-walled carbon nanotubes (SWNTs), this TTFV-fluorene exhibited strong interactions the SWNT surface, leading stable, concentrated nanotube dispersions in toluene. Photoluminescence excitation mapping indicated that selectively...
A stretchable silicon elastomer comprising cobalt ions in pyridine pendant polydimethylsiloxane (PDMS) was prepared. Different from previously reported cobalt-coordinated elastomers, these elastomers are self-healable at room temperature with a high healing efficiency of over 90%. Besides, they exhibit tailored solvatochromic properties wide range without sacrificing its self-healing ability room-temperature.
A co-coordinated PDMS@PET fabric exhibited high oil/water separation performance and rapid self-healing at room temperature.
Using molecular dynamics (MD) simulation, we studied the structural transformation and breaking mechanism of a single crystalline copper nanowire under continuous strain. At certain strain rate, an ensemble relaxed initial states can preferentially go through one or more paths deformation. In each deformation path, disordered atoms be generated at specific positions nanowire, where necking take place afterward. Such position is not predetermined; multiple lead to strain-rate-dependent,...
Given the low resection rate and chemoresistance of patients with pancreatic cancer (PC), their survival rates are typically poor. Long noncoding RNAs (lncRNAs) have recently been shown to play an important role in tumourigenesis human progression, including PC. In this study, we aimed investigate taurine-upregulated gene 1 (TUG1) A quantitative polymerase chain reaction was used analyse TUG1 expression PC tissues peritumoural normal tissues. overexpressed compared that tissues, high...
FePt nanoparticles have great potential for biomedical applications due to their superior characteristics, including superparamagnetism, resistance oxidation, and high chemical stability. The present paper reviews the methods used prepare nanoparticles, surface modifications, in field, such as biosensing, magnetic resonance imaging (MRI), targeted drug delivery, therapy.
Abstract Pancreatic cancer (PC) has a high mortality rate in all cancers worldwide. According to recent studies, long noncoding RNA‐CASC2 is involved the development and progression of many malignant tumors; present study, we demonstrated that lncRNA‐CASC2 was specifically downregulated PC tissues cell lines, lower CASC2 expression related with poorer prognosis. suppressed proliferation. Hepatocyte nuclear factor 1 alpha (HNF1A) transcription known regulate pancreatic differentiation...
Antimicrobial materials have attracted much attention all over the world. Herein, a new kind of antimicrobial material, poly (ether amide) (Pebax Ⓡ ) nanofibers containing Ag nanoparticles, was prepared by electrospinning method. The Ag/Pebax composites were characterized scanning electron microscopy (SEM), transmission (TEM), X‐ray diffraction (XRD), photoelectron spectroscopy (XPS), differential calorimetry (DSC), and thermogravimetric analyzer (TGA) measurements. properties against...
Abstract The clinical benefits of neoadjuvant chemoimmunotherapy (NACI) are demonstrated in patients with bladder cancer (BCa); however, more than half fail to achieve a pathological complete response (pCR). This study utilizes multi‐center cohorts 2322 pathologically diagnosed BCa, collected between January 1, 2014, and December 31, 2023, explore the correlation tumor budding (TB) status NACI disease prognosis. A deep learning model is developed noninvasively evaluate TB based on CT images....
Long non-coding RNA (lncRNA) X-inactive specific transcript (XIST) is involved in the development and progression of many tumors. In this study, XIST was specifically upregulated pancreatic carcinoma tissues cell lines; a higher expression correlated to poorer clinicopathologic features. After knockdown, proliferation PC lines suppressed cycle stagnated G1 phase; knockdown also reduced protein levels inhibitor apoptosis-stimulating p53 (iASPP) Cyclin-dependent kinase 1 (CDK1), increased...
In this study, we identified AlgVR7, a novel bifunctional alginate lyase from Vibrio rumoiensis and characterized its biochemical properties substrate specificity. Sequence alignment analysis inferred the key residues K267, H162, N86, E189, T244 for AlgVR7 catalysis, it is derived PL7 family; exhibited high activity towards sodium alginate, polyM (PM), polyG (PG); can also degrade polygalacturonic acid (PGA) efficiently, with highest affinity catalytic efficiency MG block of substrate. The...
A series of π-conjugated polymers made up tetrathiafulvalene vinylogue (TTFV) and phenylacetylene repeat units was synthesized investigated as supramolecular hosts for non-covalent functionalization single-walled carbon nanotubes (SWNTs). Adopting a folding conformation in the neutral state, these can effectively interact with individual SWNTs forming complexes good solubility organic solvents. Responding to certain external chemical stimuli (e.g., oxidation or protonation), however, change...
Monodisperse silver nanocages (AgNCs) with specific interiors were successfully synthesized by an azeotropic distillation (AD) assisted method and exhibited excellent catalytic activities for reduction of 4-nitrophenol (4-NP) into 4-aminophenol (4-AP) due to the unique hollow morphology small thickness shell.
MicroRNAs are ∼22 nucleotide RNAs processed from RNA hairpin structures that play important roles in regulating protein expression level via binding to mRNA, either suppressing its translation or speeding up degradation. In humans, they regulate most protein-coding genes, including genes cancer and other diseases. this study, the of microRNA-140 (miR-140) was demonstrated be significantly suppressed pancreatic duct adenocarcinoma specimens cell lines, compared with their adjacent normal...
Phenylene ethynylene-based π-conjugated polymers grafted with dithiafulvenyl groups on their side chains were found to be efficient in dispersing single-walled carbon nanotubes a selective and controllable way.
Monodisperse face-centered tetragonal (fct) FePt nanoparticles were successfully synthesized by a new and facile approach based on reverse microemulsion method, which exhibited high electrocatalytic activity in methanol oxidation.