A5102803273- Motor Control and Adaptation
- EEG and Brain-Computer Interfaces
- Muscle activation and electromyography studies
- Advanced Neuroimaging Techniques and Applications
- Pain Mechanisms and Treatments
- Neural and Behavioral Psychology Studies
- Action Observation and Synchronization
- Functional Brain Connectivity Studies
- Musculoskeletal pain and rehabilitation
- Stroke Rehabilitation and Recovery
- Neurological disorders and treatments
- Sport Psychology and Performance
- Transcranial Magnetic Stimulation Studies
- Neuroscience and Neural Engineering
- Heart Rate Variability and Autonomic Control
- Parkinson's Disease Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Autism Spectrum Disorder Research
- Neural dynamics and brain function
- Advanced MRI Techniques and Applications
- Alzheimer's disease research and treatments
- Dementia and Cognitive Impairment Research
- Behavioral Health and Interventions
- Vestibular and auditory disorders
- Pain Management and Placebo Effect
University of Florida
2016-2025
University of Florida Health
2025
Florida International University
2021
Mount Sinai Medical Center
2021
Rutgers, The State University of New Jersey
2021
University of Miami
2021
Florida College
2008-2021
Malcom Randall VA Medical Center
2013
University of Illinois Chicago
2009-2011
Nottingham University Hospitals NHS Trust
2010
The purpose of this study was to develop a high-resolution sensorimotor area tract template (SMATT) which segments corticofugal tracts based on 6 cortical regions in primary motor cortex, dorsal premotor ventral supplementary (SMA), pre-supplementary (preSMA), and somatosensory cortex using diffusion tensor imaging. Individual probabilistic tractography analyses were conducted 100 subjects the highest resolution data currently available. Tractography results refined novel algorithm...
Abstract Neurite orientation dispersion and density imaging (NODDI) uses a three‐compartment model to probe brain tissue microstructure, whereas free‐water (FW) models two‐compartments. It is unknown if NODDI detects more disease‐specific effects related neurodegeneration in Parkinson's disease (PD) atypical Parkinsonism. We acquired multi‐ single‐shell diffusion at 3 Tesla across two sites. (using multi‐shell; isotropic volume [Viso]; intracellular [Vic]; [ODI]) FW single‐shell; FW;...
There is a critical need to develop valid, non-invasive biomarkers for Parkinsonian syndromes. The current 17-site, international study assesses whether diffusion MRI (dMRI) can distinguish between
Abstract INTRODUCTION Amyloid positron emission tomography (PET) is increasingly available for diagnosis of Alzheimer`s disease (AD); however, its practical implications in heterogenous cohorts are debated. METHODS PET from 890 National Coordinating Center participants with up to 10 years post‐PET follow was analyzed. Cox proportional hazards and linear mixed models were used investigate amyloid burden prediction etiology prospective functional status cognitive decline. RESULTS positivity...
Human neuroimaging and virus-tracing studies in monkey predict that motor control pain processes should overlap anterior midcingulate cortex (aMCC), but there is currently no direct evidence this the case. We used a novel functional magnetic resonance imaging paradigm to examine brain activity while subjects performed task, experienced pain-eliciting stimulus on their hand, task also experiencing stimulus. Our experiment produced 3 results. First, group-level analyses showed when separate...
Essential tremor is a neurological syndrome of heterogeneous pathology and aetiology that characterized by primarily in the upper extremities. This commonly hypothesized to be driven single or multiple neural oscillator(s) within cerebello-thalamo-cortical pathway. Several studies have found an association blood-oxygen level-dependent (BOLD) signal pathway with essential tremor, but there behavioural evidence also points possibility severity could influenced visual feedback. Here, we...
In Brief Pain-related adaptations in movement require a network architecture that allows for integration across pain and motor circuits. Previous studies addressing this issue have focused on cortical areas such as the midcingulate cortex. Here, we focus processing human cerebellum. The goal of study was to identify activation cerebellum, which are common processing, determine whether is limited superior inferior cerebellar maps or extends into multimodal posterior Our observations...
The translation of brief, millisecond-long pain-eliciting stimuli to the subjective perception pain is associated with changes in theta, alpha, beta, and gamma oscillations over sensorimotor cortex. However, when a stimulus continues for minutes, regions beyond cortex, such as prefrontal are also engaged. Abnormalities cortex have been chronic states, but conventional, EEG paradigms do not engage regions. In current study, we collected high-density data during an experimental paradigm which...
Abstract INTRODUCTION Magnetic resonance imaging (MRI) biomarkers are needed for indexing early biological stages of Alzheimer's disease (AD), such as plasma amyloid‐β (Aβ42/40) positivity in Aβ positron emission tomography (PET) negative individuals. METHODS Diffusion free‐water (FW) MRI was acquired individuals with normal cognition (NC) and mild cognitive impairment (MCI) plasma‐/PET‐ (NC = 22, MCI 60), plasma+/PET‐ 5, 20), plasma+/PET+ (AD dementia 21) biomarker status. Gray white matter...
Autism spectrum disorder (ASD) is a lifelong condition that profoundly impacts health, independence, and quality of life. However, research on brain aging in autistic adults limited, microstructural variations white gray matter remain poorly understood. To address this critical gap, we assessed novel diffusion MRI (dMRI) biomarkers, free water, water corrected fractional anisotropy (fwcFA), mean diffusivity (fwcMD) across 32 transcallosal tracts their corresponding homotopic grey...
Abstract We examined the effectiveness of different cueing conditions during observational learning a soccer accuracy pass. Sixty participants (30 males, 30 females) were randomly assigned and stratified by sex into one six groups: discovery learning, verbal instruction, video model with visual cues, only. Each participant completed eight blocks 10 trials each, trial 1 2 representing practice phase (no manipulation), 3, 4, 5 6 acquisition (manipulation administered) 7 8 retention (24 h after...
The authors investigated the impact of emotion on performance a square-tracing task after participants (N = 40) were exposed to pleasant (P), unpleasant (U), and neutral (N) pictures. Physiological self-report measures indexed affective valence arousal. In Experiment 1, greater error followed exposure 4 consecutive U images than P images. Speed did not vary as function valence. 2, viewed 1 slide per trial within modified protocol. varied valence; faster relative stimuli. Accuracy between...
It is well established that the prefrontal cortex involved during memory-guided tasks whereas visually guided are controlled in part by a frontal-parietal network. However, nature of transition from to force control not as established. As such, this study examines spatiotemporal pattern brain activity occurs control. We measured 128-channel scalp electroencephalography (EEG) healthy individuals while they performed grip task. After visual feedback was removed, first significant change...
When humans perform movements and receive on-line visual feedback about their performance, the spatial qualities of information alter performance. The can be altered via manipulation gain changes in lead to force error. current study used functional magnetic resonance imaging during a steady-state precision grip task examine how cortical subcortical brain activity change with induced Small increases < 1° were associated substantial reduction error small increase amplitude feedback. These...
The aim of the current study was to determine extent which pleasant and unpleasant emotional states impact initiation forward gait. Participants initiated gait walked for several steps following presentation low arousing pleasant, high unpleasant, neutral pictures. Reaction time, displacement, velocity center pressure (COP) trajectory, length first second were calculated. Exposure highly pictures reduced reaction times compared all other affective conditions. Compared pictures, exposure...
Cervical dystonia (CD) is the most common type of focal dystonia, causing abnormal movements neck and head. In this study, we used noninvasive imaging to investigate motor system patients with CD uncover neural correlates dystonic symptoms. Furthermore, examined whether a commonly prescribed anticholinergic medication in has an effect on dystonia-related brain abnormalities. Participants included 16 healthy age-matched controls. We collected functional MRI scans during force task previously...