A5023705547- Lipid Membrane Structure and Behavior
- Surfactants and Colloidal Systems
- Proteins in Food Systems
- Protein Hydrolysis and Bioactive Peptides
- Supramolecular Self-Assembly in Materials
- Electrostatics and Colloid Interactions
- Protein Interaction Studies and Fluorescence Analysis
- Polymer Surface Interaction Studies
- Polydiacetylene-based materials and applications
- Advanced Polymer Synthesis and Characterization
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanopore and Nanochannel Transport Studies
- Phytase and its Applications
- Hydrogels: synthesis, properties, applications
- Nanocluster Synthesis and Applications
- Dendrimers and Hyperbranched Polymers
- Polymer Nanocomposites and Properties
- Spectroscopy and Quantum Chemical Studies
- Block Copolymer Self-Assembly
- RNA Interference and Gene Delivery
- Polymer crystallization and properties
- biodegradable polymer synthesis and properties
- Pickering emulsions and particle stabilization
- Nuclear Physics and Applications
- Polymer composites and self-healing
Semmelweis University
2024-2025
Eindhoven University of Technology
2022-2025
Institute of Biophysics
2025
Eötvös Loránd University
2020-2023
Aarhus University
2019-2023
HUN-REN Research Centre for Natural Sciences
2020-2022
Institute of Materials and Environmental Chemistry
2020-2022
HUN-REN Centre for Energy Research
2021-2022
Size characterization of extracellular vesicles (EVs) and drug delivery liposomes is great importance in their applications diagnosis therapy diseases. There are many different size techniques used the field, which often report values. Besides technological biases, these differences originate from fact that various methods measure physical quantities to determine particle size. In this study, synthetic with nominal diameters 50nm 100nm, red blood cell-derived EVs (REVs) were measured...
Biodegradable, biocompatible nanoparticles with tuneable fluorescence - due to their great potential in biology, medicine and sensor development are widely studied nowadays. Recently it was shown that the complex red emitting spectroscopic feature of Bovine Serum Albumin gold (BSAAu) bioconjugates can be related versatility conformational changes BSA protein. In our study, we performed a comprehensive study on structural host molecules by infrared spectroscopy (FTIR) small-angle X-ray...
Small-angle X-ray and neutron scattering (SAXS SANS) are versatile techniques for studying the structure of various materials particles, enabling investigations structures from a few to hundreds nanometres. However, interpreting SAXS or SANS data can be challenging, hence need effective training. Here, we present website SAStutorials.org, which offers tutorials on small-angle (SAS) analysis. The serves as learning platform that supports active both in classroom through self-study. cover...
Predicting 3D structures of synthetic heterograft polymers in solution starting from a chemical structure remains great challenge. Here, we get grip on the formed by amphiphilic, random water depending nature hydrophilic graft. Atomistic MD simulations explicit μs time scale show that large Jeffamine-based grafts combined with randomly distributed hydrophobic induce formation worm-like local domains. Replacing Jeffamine glucose affords core–shell ellipsoidal structures. The simulated...
The self-assembly of two oppositely charged diblock copolymers that have a common thermosensitive nonionic block poly(N-isopropylacrylamide) (pNIPAAM) has been investigated. effect the mixing ratio and total polymer concentrations on components phase stability mixtures was studied by dynamic light scattering, electrophoretic mobility, turbidimetry measurements in water at 20 °C. competing electrostatic hydrophobic interactions nanostructure negatively electrostatically self-assembled...
In the last 20 years, it has been demonstrated that oppositely charged polyelectrolyte-surfactant (PE-S) mixtures are prone to forming kinetically arrested non-equilibrium aggregates, which present in prepared from rather low surfactant-to-polymer-repeat-unit ratios. Practically, this means PE-S used for structural investigations of formed complexes typically a mixture primary and large aggregates close charge-neutral complexes.In work, we unique approach allows preparation equilibrium...
The interfacial structure and morphology of films spread from hyperbranched polyethylene imine/sodium dodecyl sulfate (PEI/SDS) aggregates at the air/water interface have been resolved for first time with respect to polyelectrolyte charged density. A recently developed method form efficient dissociation using a minimal quantity materials is exploited as step forward in enhancing understanding film properties view their future use technological applications. Interfacial techniques that...
Thylakoid membranes are energy-converting with a unique lipid composition. Though the primarily composed of proteins, their photosynthetic function is strongly influenced by constituents. Here we characterize, molecular dynamics (MD) simulations, bilayers compositions representative plant thylakoid membranes. We determine, in wide range temperatures, physical parameters model which relevant for function. found marked impact temperature on membrane permeability due to combination increased...
Self-immolative chemistries that respond in an irreversible manner to external stimuli are highly attractive permanently degrade filamentous supramolecular biomaterials. Within the monomer, a balance needs be struck between its capacity supramolecularly polymerized and degraded at appropriate rate for given application. Herein, we unravel structure-property-function relationships of library squaramide-based bolaamphiphiles bearing central disulfide-based self-immolative spacer construct...
When the separated erythrocyte membranes (known as ghosts) are ultrasonicated, a significant part of membrane proteins released in aqueous solvent, instead being incorporated into formed nanoerythrosomes. In contrast to their membrane-bound counterparts, where helices and β-strands dominate, show perturbed secondary structures with an increased ratio helices, presumably participating molten globules, it has been revealed by circular dichroism (CD) infra-red spectroscopy (IR). The shape size...
Water-soluble supramolecular polymers show great potential to develop dynamic biomaterials with tailored properties. Here, we elucidate the morphology, stability and dynamicity of derived from bisurea-based monomers. An accessible synthetic approach 2,4-toluene diisocyanate (TDI) as starting material is developed. TDI has two isocyanates that differ in intrinsic reactivity, which allows obtain functional, desymmetrized monomers a one-step procedure. We explore how hydrophobic/hydrophilic...
Thermoresponsive polymers, with special emphasis on poly(N-isopropylacrylamide) (PNIPAAM) have been the focus of several investigations due to its potential applications in many fields physical and polymer chemistry. PNIPAAM has a "lower critical solution temperature" at 32°C. The LCST can be finely tuned by copolymerization hydrophobic or hydrophilic comonomers, change chemical parameters, such as ionic strength solution. We investigated effect concentration two different environment, pure...
The red-emitting fluorescent properties of bovine serum albumin (BSA)-gold conjugates are commonly attributed to gold nanoclusters formed by metallic and ionized atoms, stabilized the protein. Others argue that red fluorescence originates from cation-protein complexes instead, not nanoclusters. Our infrared spectroscopy, neutron, X-ray small-angle scattering measurements show structural behavior BSA-Au different in normal heavy water, strengthening argument for existence loose ionic...