Jianhua Liu

ORCID: 0000-0001-8628-0127
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About
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Research Areas
  • Ultrasound and Hyperthermia Applications
  • Acupuncture Treatment Research Studies
  • Photoacoustic and Ultrasonic Imaging
  • Hepatitis Viruses Studies and Epidemiology
  • Healthcare and Venom Research
  • Nanoplatforms for cancer theranostics
  • MRI in cancer diagnosis
  • Hepatitis B Virus Studies
  • Abdominal Trauma and Injuries
  • Neonatal and fetal brain pathology
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Ultrasound and Cavitation Phenomena
  • Viral gastroenteritis research and epidemiology
  • Wireless Communication Networks Research
  • Blind Source Separation Techniques
  • Advanced Wireless Communication Techniques
  • Tendon Structure and Treatment
  • Nanopore and Nanochannel Transport Studies
  • Liver Disease Diagnosis and Treatment
  • Neurological Disease Mechanisms and Treatments
  • Cytomegalovirus and herpesvirus research
  • Advanced Wireless Network Optimization
  • Biofield Effects and Biophysics
  • Liver Diseases and Immunity
  • Angiogenesis and VEGF in Cancer

South China University of Technology
2010-2025

Guangzhou Medical University
2009-2025

Guangzhou First People's Hospital
2002-2025

Guangdong Provincial Hospital of Traditional Chinese Medicine
2015-2025

Zhejiang University of Water Resource and Electric Power
2025

Guangzhou University of Chinese Medicine
2020-2024

Guangzhou University
2023

Shandong Jianzhu University
2011-2022

First Affiliated Hospital of Jinan University
2021-2022

Shandong University
2006-2022

In China, hepatitis E virus (HEV) is prevalent and causes disease, but its epidemiological profile not well understood. We used a commercial enzyme-linked immunosorbent assay to detect total antibodies in 15,862 serum samples collected during the Third National Viral Hepatitis Prevalence Survey. The results were analyzed calculate estimates of HEV seroprevalence examine effects some putative risk factors. general Chinese population period from 2005 through 2006 was 23.46% (95% confidence...

10.1371/journal.pone.0110837 article EN cc-by PLoS ONE 2014-10-31

Introduction Tumor tissues exhibit significantly lower oxygen partial pressure compared to normal tissues, leading hypoxia in the tumor microenvironment and result resistance treatments. Strategies mitigate include enhancing blood perfusion supply, for example,by decomposing hydrogen peroxide within tumor. Improving could potentially improve efficacy of cancer Previous studies have demonstrated that ultrasound appropriate intensity when combined with microbubbles, can perfusion. However, its...

10.3389/fphar.2024.1502349 article EN cc-by Frontiers in Pharmacology 2025-01-13

To investigate the effect and mechanism of electroacupuncture (EA) at "Siguan" acupoints (bilateral Hegu [LI4] bilateral Taichong [LR3]) in ameliorating facial nerve injury-induced anxiety-like behavior mice. Thirty male C57BL/6J mice were randomly divided into control, model (unilateral injury), EA groups, with 10 each group. The injury was established by lightly clamping isolated for about 30 s, twice altogether after operation. group subjected to stimulation (2 Hz, 0.5 mA) LI4 LR3 min,...

10.13702/j.1000-0607.20240789 article EN PubMed 2025-01-25

Rationale: Following the structural destruction of annulus fibrosus (AF), early-stage damage manifests as symptoms such an inflammatory phenotype and loss mechanical support. The microenvironmental deterioration at injury site, limited population, inadequate differentiation intrinsic stem/progenitor cells impede efficient repair AF. To address aforementioned challenges, we developed a dual-drug-loaded hydrogel system to achieve systematic functional tissue repair. Methods: A tannic...

10.7150/thno.106913 article EN cc-by Theranostics 2025-04-21

Abstract The study of molecule transport within confined nanochannels is crucial to developing high‐performance membranes. Previous studies mainly focus on the interfacial transport; however, central transport, equally crucial, has been disregarded. Herein, vertically aligned vermiculite‐based (Vr‐based) membranes with long‐range are engineered ensure a stable flow. Meanwhile, channel surfaces functionalized (–CH 3 , –NH 2 and –CF groups) tune interaction molecules, thus affecting...

10.1002/aic.18893 article EN AIChE Journal 2025-05-08

As the theoretical core of acupuncture and moxibustion traditional Chinese medicine, meridian-collateral theory is an original medical unique to China, which embodies wisdom ancient medicine practitioners. The phenomenon stepping-stone success meridian research, most its research ideas are based on finding a pipeline system along meridian. Due fact that anatomical basis meridians has still not been made clear, there many phenomena reported, but they generally have problems such as low...

10.13702/j.1000-0607.20250087 article EN PubMed 2025-05-25

Interstitial fluid pressure (IFP) in tumor tissue was significantly higher than normal tissue, which reduced the effective of therapeutic drugs. There are many methods to decrease IFP level, such as normalizing blood vessel, decreasing content hyaluronic acid and collagen fibers extracellular matrix (ECM), recovering lymphatic function. Reducing may become a new way cancer therapy. Our research aimed focus on relationship mechanism between ultrasound combined with microbubble therapy IFP....

10.3389/fphar.2019.00716 article EN cc-by Frontiers in Pharmacology 2019-06-26

This study sought to (1) assess the effectiveness of acupuncture and moxibustion with a method soothing liver regulating mind on quality life among patients depression (2) sex differences in treatment basis patient-reported outcomes.In single-blind, randomized, controlled trial conducted Guangdong Province, China, January December 2010, 163 who met criteria for were enrolled. Eligible allocated three groups (soothing group, acupoint shallow puncturing non-acupoint group). In all groups, was...

10.1089/acm.2015.0068 article EN The Journal of Alternative and Complementary Medicine 2015-08-20

Numerous nanomedicines have been developed recently that can accumulate selectively in tumours due to the enhanced permeability and retention (EPR) effect. However, high interstitial fluid pressure (IFP) solid limits targeted delivery of nanomedicines. We were previously able relieve intra-tumoural IFP by low-frequency non-focused ultrasound (LFNFU) through ultrasonic microbubble destruction (UTMD), improving FITC-dextran. accumulation nanoparticles different sizes optimal acoustic not...

10.1080/1061186x.2024.2367579 article EN Journal of drug targeting 2024-06-17

Microbubble-enhanced therapeutic ultrasound (MEUS) can block the blood flow in organs. The aim of this study was to evaluate hemostatic effect microbubble-enhanced pulsed, low-intensity a New Zealand White rabbit model avulsion trauma liver. (TUS) transducer operated with frequency 1.2 MHz and an acoustic pressure 3.4 MPa. Microbubble-(MB) enhanced (n = 6) delivered distal part liver where created. Livers were treated by TUS only 4) or MB which served as controls. Bleeding rates measured...

10.1371/journal.pone.0095589 article EN cc-by PLoS ONE 2014-05-01

Dengue has become a serious public health problem in southern China particularly with record-breaking outbreak 2014. Serological evidence from areas no known dengue cases reported prior to 2014 could provide information on possible unrecognized circulation of virus (DENV) before this outbreak. Between March and May 2015, we performed cross-sectional serosurvey using stratified random sampling method among individuals aged 1-84 years-old 7 communities Guangzhou Sera subjects were initially...

10.1093/ofid/ofz256 article EN cc-by-nc-nd Open Forum Infectious Diseases 2019-06-03

Objectives . One reason for the high recurrence and metastatic rates of tumors such as hepatocellular carcinoma (HCC) treated by microwave ablation (MWA) is presence residual foci in tumor due to heat sink effect. Microbubble-enhanced ultrasound (MEUS) can noninvasively disrupt block blood perfusion has potential overcome effect enhance therapeutic MWA. The study aimed at evaluating additional benefit microbubble-enhanced (MWA). Methods In this study, a new strategy combining MWA with MEUS...

10.1155/2020/3050148 article EN cc-by BioMed Research International 2020-01-23

To evaluate the hepatitis A vaccine coverage among 2-29 year olds and reported incidence rates of A, in China.Based on data from national sero-survey B 2014, information immunization was collected analyzed with SAS software (Version 9.4). Incidence also National Notifiable Disease Reporting System between 2004 using micro-software Excel 2007.Totally, involving 29 058 people aged years were available for analysis overall 44.6%. The younger age, higher appeared. Among 2-6 7-14 olds, 91.2%...

10.3760/cma.j.issn.0254-6450.2016.08.009 article EN PubMed 2016-08-10

Tanshinone IIA was identified as a novel natural MAGL inhibitor by an <italic>in silico</italic> approach combined with vitro</italic> experimental analysis.

10.1039/c4md00186a article EN MedChemComm 2014-01-01

BACKGROUND This study embarked on an innovative exploration to elucidate the effects of integrating electroacupuncture (EA) with motor training (MT) enhancing corticospinal excitability and learning. Central this investigation is interplay between homeostatic non-homeostatic metaplasticity processes, providing insights into how these combined interventions may influence neural plasticity skill acquisition. MATERIAL AND METHODS The enrolled 20 healthy volunteers, subjecting them 4 distinct...

10.12659/msm.943748 article EN cc-by-nc-nd Medical Science Monitor 2024-04-26

The tumor microenvironment is increasingly acknowledged as a critical contributor to cancer progression, mediating genetic and epigenetic alterations. Beyond diverse cellular interactions from the microenvironment, physicochemical factors such acidosis also significantly affect dynamics. Recent research has highlighted that facilitates invasion, immune escape, metastasis, resistance therapies. Thus, noninvasive measurement of acidity development targeted interventions represent promising...

10.3389/fonc.2024.1424824 article EN cc-by Frontiers in Oncology 2024-07-18

To investigate the causes of damage dispersion in fatigue life alloy materials, tests on 42CrMo are carried out under microscope with aid a micro testing device. The crack initiation and propagation evolution process studied micromechanical scale. short growth rates measured respectively loads 1400, 1550, 1650 N. experimental result shows that cracks is related to randomness microstructure defects. surface samples random local, while characterized by first deceleration then acceleration.

10.1177/16878140211073206 article EN cc-by Advances in Mechanical Engineering 2022-03-01

We conducted a multi-center study to investigate the prevalence, malignant transformation potential of simple renal cysts and factors that might predict malignancy. defined as Bosniak class I & II (including IIF) lesions. In prevalence study, data from 115,132 ultrasonographies was collected individuals who participated in multiphasic health wellness screen. natural history progression we retrospectively reviewed 333 participants with were followed for at least 3 years mean 6.3±2.9 (ranged...

10.21037/tau.2020.03.29 article EN Translational Andrology and Urology 2020-04-01
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