A5044033060- Endometrial and Cervical Cancer Treatments
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Ovarian cancer diagnosis and treatment
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Cervical Cancer and HPV Research
- Pregnancy and preeclampsia studies
- Intraperitoneal and Appendiceal Malignancies
- Atherosclerosis and Cardiovascular Diseases
- Reproductive Biology and Fertility
- Ectopic Pregnancy Diagnosis and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy-related medical research
- Health Systems, Economic Evaluations, Quality of Life
- Minimally Invasive Surgical Techniques
- Quality and Safety in Healthcare
- Colorectal Cancer Surgical Treatments
- Medical and Biological Sciences
- Abdominal Surgery and Complications
- Glycosylation and Glycoproteins Research
- Vascular anomalies and interventions
- Carbohydrate Chemistry and Synthesis
- Reproductive System and Pregnancy
- Hernia repair and management
Osaka International Cancer Institute
2021-2025
Osaka University
2025
Takarazuka City Hospital
2020-2022
To examine the association between intrauterine manipulator use and pathological factors oncologic outcomes in patients with endometrial cancer who had laparoscopic hysterectomy Japan. This was a nationwide retrospective cohort study of tumor registry Japan Society Obstetrics Gynecology. Study population 3846 for from January 2015 to December 2017. An automated 1-to-1 propensity score matching preoperative intraoperative demographics performed assess postoperative associated manipulator....
We investigated clinical implications of CRP and its receptor, LOX-1, in cervical cancer progression the underlying mechanisms. Clinical data from 121 patients with administered definitive radiotherapy were analyzed to investigate relationship among pretreatment serum levels, tumor LOX-1 expression, treatment outcomes. samples, cell lines, mouse xenograft models employed elucidate mechanisms for CRP-mediated cancer, focusing on expression myeloid-derived suppressor (MDSCs) cells. Patients...
Many urinary free-glycan markers were identified in our previous studies. Here, the clinical utility of these was examined. Urine samples taken from 120 healthy subjects and 503 patients with various malignant tumors analyzed. Four lactose-core glycans containing N-glycolylglucosamine (GlcNGc) synthesized used as internal standards (ISs). Free-glycans isolated using a two-step column purification procedure, pyridylaminated, subjected to LC-selected reaction monitoring. Assay validation...
Abstract Objective This study aimed to investigate the prognostic significance of tumor size and number positive pelvic lymph nodes (PLN) in International Federation Gynecology Obstetrics (FIGO) 2018 stage IIIC1 cervical cancer patients. Methods Clinical data from 626 women with treated at Osaka Cancer Center 2010–2020 were retrospectively reviewed. Using cutoff value obtained on receiver operating characteristic analysis, PLN patients was first evaluated via uni- multivariate analyses....
This study examined the effect of hospital surgical volume on oncologic outcomes in minimally invasive surgery (MIS) for gynecologic malignancies. The objectives were to assess survival related and evaluate perioperative examine non-gynecologic Literature available from PubMed, Scopus, Cochrane Library databases systematically reviewed. All procedures including with information eligible analysis. Twenty-three studies met inclusion criteria, nine gastro-intestinal studies, seven genitourinary...
We aimed to compare the oncological outcomes between Japanese women with uterine-confined and node-negative cervical cancer who underwent open surgery those minimally invasive (MIS). A population-based retrospective cohort study was conducted using data from Osaka Cancer Registry that ranged 2011 2018. total of 2279 patients surgical treatment for were identified. The classified into groups according type (open MIS groups) year diagnosis (group one, 2011–2014; group two, 2015–2018)....
To compare the oncological outcomes between Japanese women who underwent minimally invasive surgery and those open for early-stage endometrial cancer.This population-based retrospective cohort study was conducted using data from Osaka Cancer Registry 2011 to 2018. Surgically treated patients localized (uterine-confined) cancer were identified. Patients classified into two groups according type of (minimally group open-surgery group), pathological risk factors (low-risk high-risk), year...
We retrospectively investigated the significance of metastatic lymph nodes in patients with locally recurrent or persistent cervical cancer a previously irradiated field and subsequently had salvage hysterectomy. Clinical data were obtained from chart review, prognostic impact presence, number (1–2 versus ≥3), location (pelvic pelvic plus para-aortic) node metastasis was by comparing recurrence survival. In total, 50 included this study, which 21 (42.0%) showed pathological evidence...
Abstract Seromucinous borderline tumors (SMBT) are papillary neoplasms without invasive capabilities. Originally categorized as ovarian tumors, SMBT, being an endometriosis‐related tumor, can manifest beyond the ovaries. To date, only four cases of extraovarian SMBT have been documented in literature. In this report, we present our experience with first case uterine cervix, which exhibited highly elevated CA19‐9 levels. The patient, initially clinically diagnosed cervical cancer, underwent...
Abstract Aim To compare the surgical and oncologic outcomes between patients with locally recurrent cervical cancer undergoing robotic‐assisted salvage radical hysterectomy (RH) those conventional open RH, performed by a single surgeon. Methods This retrospective comparative observational study utilized data obtained from consecutive cancer, developed after definitive radiotherapy. These either underwent robot‐assisted RH (robotic group) or (open group). Clinicopathological characteristics,...