A5039868487- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Congenital Heart Disease Studies
- Cardiac Imaging and Diagnostics
- Autism Spectrum Disorder Research
- Acute Myocardial Infarction Research
- Cognitive and developmental aspects of mathematical skills
- Family and Disability Support Research
- Cardiac Valve Diseases and Treatments
- Reading and Literacy Development
- Digital Radiography and Breast Imaging
- Consumer Attitudes and Food Labeling
- Eosinophilic Esophagitis
- Radiation Dose and Imaging
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Attention Deficit Hyperactivity Disorder
- Hemodynamic Monitoring and Therapy
- Muscle Physiology and Disorders
- Genetic Neurodegenerative Diseases
- Cardiovascular Issues in Pregnancy
- Gastroesophageal reflux and treatments
St. Patrick Hospital
2024
Providence College
2024
University of Washington
2015-2024
Samaritan Health Services
2023
The University of Sydney
2022-2023
University of Washington Medical Center
2023
Mercy Hospital
2022
Children's Mercy Hospital
2022
Robinson Memorial Hospital
2022
The University of Texas MD Anderson Cancer Center
2022
Heart failure remains a significant cause of morbidity and mortality following myocardial infarction. Cardiac remuscularization with transplantation human pluripotent stem cell-derived cardiomyocytes is promising preclinical therapy to restore function. Recent large animal data, however, have revealed risk engraftment arrhythmia (EA). Although transient, the posed by EA presents barrier clinical translation. We hypothesized that clinically approved antiarrhythmic drugs can prevent EA-related...
Background: Critically ill patients often require invasive monitoring to evaluate and optimize cardiac function preload. With questionable outcomes associated with pulmonary artery catheters (PACs), some have evaluated the role of less monitors. We hypothesized that Bedside Echocardiographic Assessment in Trauma (BEAT) examination would generate index (CI) central venous pressure (CVP) estimates correlate a PAC. Methods: BEAT was performed on all SICU PAC place. Prospective data included...
VT Ablation Treatment of Last Resort. Introduction: Despite advances in ablation ventricular tachycardia (VT), recognized toxicity amiodarone, and potential harm implantable cardioverter defibrillator (ICD) shocks, there appears to be reluctance pursue catheter ablation. Methods Results: We tested the hypothesis that patients with structural heart disease are referred late for may have worse outcomes as a result. Consecutive single center, between January 2008 April 2009 were studied....
Ventricular tachycardia (VT) is associated with high mortality in patients cardiac sarcoidosis (CS), and medical management of CS-associated VT limited by failure rates. The role catheter ablation has been investigated small, single-center studies.To investigate outcomes CS.This cohort study from the Cardiac Sarcoidosis Consortium registry (2003-2019) included 16 tertiary referral centers US, Europe, Asia. A total 158 consecutive CS were (33% female; mean [SD] age, 52 [11] years; 53%...
Prior reports demonstrate prognostic value in noninducibility of atrial arrhythmias after fibrillation (AF) ablation and suggest their utility guiding additional lesion sets. The type mechanism induced arrhythmias, relationship to the underlying substrate, significance organized are unknown.One hundred forty-four patients (30 women; median age 60 years; 54% with paroxysmal AF) undergoing AF (circumferential pulmonary vein isolation focal nonvein triggers on isoproterenol) were evaluated...
Spinobulbar muscular atrophy and Huntington's disease are caused by polyglutamine expansion in the androgen receptor huntingtin, respectively, their pathogenesis has been associated with abnormal nuclear localization aggregation of truncated forms these proteins. Here we show, diverse cell types, that glucocorticoids can up- or down-modulate expanded polypeptides derived from huntingtin through specific regulation gene expression. Wild-type glucocorticoid (GR), as well C-terminal deletion...
Sudden death is a leading cause of mortality in sickle cell disease, implicating ventricular tachyarrhythmias. Prolonged QTc on an electrocardiogram (ECG), commonly seen with myocardial ischemia, known risk for polymorphic tachycardia (VT). We hypothesized that prolonged associated disease. ECG were analyzed from cohort 224 patients (University Illinois at Chicago, UIC) along available laboratory, and echocardiographic findings, another 38 UC) which cardiac MRI free heme values also...
Ninety-six first grade students in an urban school system were tested October and May on reading, mathematics, their understanding of sequences letters numbers. A time lag analysis was subsequently conducted. In such analyses, cross-correlations between the measurement one variable second another are compared. The larger correlations indicates direction relationship; i.e., which is most likely to be causal. Correlations fall scores number with spring mathematics concepts scale significant,...
Abstract Introduction Late‐gadolinium enhancement magnetic resonance (LGE‐MRI) imaging is increasingly used in management of atrial fibrillation (AFib) patients. Here, we assess the usefulness LGE‐MRI‐based fibrosis quantification to predict arrhythmia recurrence patients undergoing cryoballoon ablation. Our secondary goal was compare two widely methods. Methods In 102 AF LGE‐MRI and ablation (mean age 62 years; 64% male; 59% paroxysmal AFib), quantified using pixel intensity histogram (PIH)...
The Role of Cognitive Flexibility in Pattern Understanding Allison Bock, Kelly B. Cartwright, Christian Gonzalez, Sarah O'Brien, Melissa F. Robinson, Katrina Schmerold, Amber Shriver, Robert Pasnak Abstract ability to discover a regularity among an ordered set units, termed patterning, is crucial cognitive that precedes pre-algebraic mathematics skills and possibly reading. However, there limited research on the underpinnings patterning. There some suggestion relation between flexibility,...
Research indicates that youth with autism spectrum disorder often experience unmet health care needs and receive poorer quality of care. Intellectual disability commonly co-occurs disorder; however, the nature in intellectual have not been investigated. As such, this study sought to examine associations among co-occurring disability, physical mental needs, disorder. Data from were acquired 2016–2018 National Survey Children’s Health, a nationally distributed caregiver-report questionnaire....
This study examined the effects of reading modality (oral vs. silent) on comprehension in elementary school students with a specific learning disability ( N = 77). A 2 (development-level) × (reading modality) (time) mixed factorial analysis variance (ANOVA) was conducted to determine influence these variables comprehension. Significant main were found for and time comprehension, but effect developmental level not significant. Students understood more what read orally than silently showed...
Reentrant Circuit of Typical Atrial Flutter . Background: Reentry utilizing cavotricuspid isthmus (CTI) is accepted as the mechanism underlying typical atrial flutter (AFLT). However, it unclear how right (RA) posterior wall (PW) participates in AFLT circuit. We sought to investigate this by using noncontact electroanatomic mapping. Methods: Fifteen patients (pts) undergoing ablation for participated. Multipolar catheters were deployed RA and coronary sinus. shell was created during AFLT....