Dale Whittington

ORCID: 0000-0002-6075-8812
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About
Contact & Profiles
Research Areas
  • Water resources management and optimization
  • Child Nutrition and Water Access
  • Economic and Environmental Valuation
  • Transboundary Water Resource Management
  • Water Governance and Infrastructure
  • Global Maternal and Child Health
  • Fiscal Policy and Economic Growth
  • Poverty, Education, and Child Welfare
  • Pharmacological Effects and Toxicity Studies
  • Pharmacogenetics and Drug Metabolism
  • Hydropower, Displacement, Environmental Impact
  • Drug Transport and Resistance Mechanisms
  • Vibrio bacteria research studies
  • Housing Market and Economics
  • Salmonella and Campylobacter epidemiology
  • Energy and Environment Impacts
  • Vaccine Coverage and Hesitancy
  • Decision-Making and Behavioral Economics
  • Urban and Rural Development Challenges
  • COVID-19 epidemiological studies
  • Health Systems, Economic Evaluations, Quality of Life
  • Climate Change Policy and Economics
  • International Development and Aid
  • Water-Energy-Food Nexus Studies
  • Water Systems and Optimization

University of Washington
2016-2025

University of North Carolina at Chapel Hill
2015-2024

University of Manchester
2014-2024

Seattle University
2022

Center for Global Development
2019-2020

National University of Singapore
2016-2019

Institute of Development Studies
2018-2019

Heinrich Heine University Düsseldorf
2018

University of Duisburg-Essen
2018

Manchester School of Architecture
2008-2017

A better understanding of household water use in developing countries is necessary to manage and expand systems more effectively. Several meta-analyzes have examined the determinants demand industrialized countries, but little effort has been made synthesize growing body literature evaluating countries. This article reviews what known missing from that thus far. Analysis for complicated by abundant evidence that, contrary observed most developed households access to, may than one several...

10.1093/wbro/lkp016 article EN The World Bank Research Observer 2009-11-11

Abstract When construction of the Grand Ethiopian Renaissance Dam (GERD) is completed, Nile will have two world’s largest dams—the High Aswan (HAD) and GERD—in different countries (Egypt Ethiopia). There not yet agreement on how these dams operate to manage scarce water resources. We elucidate potential risks opportunities Egypt, Sudan Ethiopia by simulating filling period reservoir; a new normal after reservoir fills; severe multi-year drought filling. Our analysis illustrates during HAD...

10.1038/s41467-020-19089-x article EN cc-by Nature Communications 2020-10-16

10.1023/a:1015575517927 article EN Environmental and Resource Economics 2002-01-01

This paper investigates two complementary pieces of data on households' demand for improved water services, coping costs and willingness to pay (WTP), from a survey 1500 randomly sampled households in Kathmandu, Nepal. We evaluate how WTP vary across types users income. find that Kathmandu Valley engage five main behaviors: collecting, pumping, treating, storing, purchasing. These activities impose an average household as much 3 U.S. dollars per month or about 1% current incomes,...

10.1029/2003wr002443 article EN Water Resources Research 2005-02-01

This paper reports the main findings of a multi-country research project designed to develop better understanding performance community-managed rural water supply systems in developing countries. Data were collected from households, village committees, focus groups residents, system operators and key informants 400 communities Peru, Bolivia Ghana. Our suggest that demand-driven, community management model, coupled with access spare parts some technical expertise, has come long way toward...

10.2166/wp.2009.310 article EN Water Policy 2009-10-01

Two nonmarket valuation techniques-the contingent method and travel cost model-are used to estimate the economic value that people in Davao, Philippines, place on improving water quality of rivers sea near their community. The estimates are very close each other quite low, both absolute terms as a percentage household income. These findings suggest pollution control is simply not high priority for Davao's residents, support argument households' willingness pay environmental amenities such...

10.2307/3146913 article EN Land Economics 1996-11-01

Background Metabolism and clearance of racemic methadone are stereoselective highly variable, yet the mechanism remains largely unknown. Initial in vitro studies attributed metabolism to cytochrome P4503A4 (CYP3A4). CYP3A4 was also assumed responsible for vivo. Nevertheless, recent clinical data do not support a primary role suggest that CYP2B6 may mediate clearance. Expressed CYP2C19 N-demethylate vitro. This investigation tested hypothesis CYPs 2B6, 3A4, and/or 2C19 human liver microsomes...

10.1097/aln.0b013e3181642938 article EN Anesthesiology 2008-03-01

Abstract This article presents a methodology for planning new water resources infrastructure investments and operating strategies in world of climate change uncertainty. It combines real options (e.g., to defer, expand, contract, abandon, switch use, or otherwise alter capital investment) approach with principles drawn from robust decision‐making (RDM). RDM comprises class methods that are used identify investment perform relatively well, compared the alternatives, across wide range...

10.1002/2013wr013705 article EN Water Resources Research 2014-03-01

Significance The outer membrane (OM) of Gram-negative bacteria is composed lipopolysaccharide (LPS) and glycerophospholipids (GPLs). Environmental regulation LPS promotes bacterial resistance to host cationic antimicrobial peptides by altering surface charge hydrophobicity. This work demonstrates that pathogenic Salmonella coordinately regulate GPL through the PhoPQ regulatory proteins OM palmitoyltransferase enzyme PagP. broad conservation PagP in suggests environmental may be a conserved...

10.1073/pnas.1316901111 article EN Proceedings of the National Academy of Sciences 2014-01-21

10.1016/j.bbalip.2017.02.002 article EN Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2017-02-09

Benefit-cost analysis and other forms of economic evaluation are powerful tools, encouraging the systematic collection assessment evidence needed to support sound policy decisions. In low-and middle-income countries, where resources very scarce needs great, such decisions particularly difficult can be especially useful. If not well conducted clearly reported, however, these studies lead erroneous conclusions. Differences in analytic methods assumptions also obscure important differences...

10.2139/ssrn.4015886 article EN SSRN Electronic Journal 2019-01-01

Abstract The landscape of water infrastructure in the Nile Basin is changing with construction Grand Ethiopian Renaissance Dam. Although this dam could improve electricity supply Ethiopia and its neighbors, there a lack consensus between Ethiopia, Sudan, Egypt on operation. We introduce new modeling framework that simulates River System Egypt’s macroeconomy, dynamic feedbacks river system macroeconomy. Because two systems “coevolve” throughout multi-year simulations, we term “coevolutionary”...

10.1038/s41467-021-25877-w article EN cc-by Nature Communications 2021-09-23

Heart failure remains a significant cause of morbidity and mortality following myocardial infarction. Cardiac remuscularization with transplantation human pluripotent stem cell-derived cardiomyocytes is promising preclinical therapy to restore function. Recent large animal data, however, have revealed risk engraftment arrhythmia (EA). Although transient, the posed by EA presents barrier clinical translation. We hypothesized that clinically approved antiarrhythmic drugs can prevent EA-related...

10.1016/j.stemcr.2021.08.005 article EN cc-by Stem Cell Reports 2021-09-09

Nation‐states rarely go to war over water, but it is equally rare that water conflicts in an international river basin are resolved through cooperation among the riparian countries use shared resources. Gains from will mean little individual riparians unless required cooperative behaviors incentive compatible. Cooperative game theory offers useful insights for assessing solutions basins. Applying concepts such as core, nucleolus, and Shapley value Nile conflicts, we examine structure of both...

10.1029/2005wr004238 article EN Water Resources Research 2006-02-01

Since 1999 a multilateral effort termed the Nile Basin Initiative has been underway among riparians to explore opportunities for maximizing benefits of river's waters through cooperative development and management basin. However, date there virtually no explicit discussion economic value water resources development. We believe that serious discourse about economics cooperation is both inevitable desirable, this will not diminish importance environmental, social, or cultural issues new...

10.2166/wp.2005.0015 article EN Water Policy 2005-06-01

This paper presents a typology of international rivers based on asymmetries in economic and political power among riparian states. is then used, along with other factors such as the spatial location riparians river, to explore question why some have been able successfully negotiate treaties others not. The findings lend support both economy explanations cooperative action rivers. International countervailing are far more likely negotiated than river types. Riparian states sharing “western...

10.1029/2003wr002536 article EN Water Resources Research 2004-05-01
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