A5033520563- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Antibiotics Pharmacokinetics and Efficacy
- Cancer-related molecular mechanisms research
- Nosocomial Infections in ICU
- Anesthesia and Pain Management
- COVID-19 Clinical Research Studies
- Antibiotic Resistance in Bacteria
- COVID-19 Impact on Reproduction
- Hemodynamic Monitoring and Therapy
- Circular RNAs in diseases
- Pneumothorax, Barotrauma, Emphysema
- Palliative Care and End-of-Life Issues
- Thermal Regulation in Medicine
- Emergency and Acute Care Studies
- SARS-CoV-2 and COVID-19 Research
- RNA modifications and cancer
- Pleural and Pulmonary Diseases
- Vitamin C and Antioxidants Research
- Inflammatory Biomarkers in Disease Prognosis
- Anesthesia and Sedative Agents
- Pneumonia and Respiratory Infections
- MicroRNA in disease regulation
- Cardiac Arrest and Resuscitation
- Vitamin D Research Studies
Imam Hossein Hospital
2018-2025
Shahid Beheshti University of Medical Sciences
2012-2025
Isfahan University of Medical Sciences
2025
Masih Daneshvari Hospital
2012
Despite 2.5 million infections and 169,000 deaths worldwide (as of April 20, 2020), no maternal only a few pregnant women afflicted with severe respiratory morbidity have been reported to be related COVID-19 disease. Given the disproportionate burden fatal disease previously documented among following other coronavirus-related outbreaks (SARS-CoV in 2003 MERS-CoV 2012) influenza pandemics over last century, absence mortality is unexpected.To describe perinatal outcomes death case series...
To determine if real-time compression feedback using a non-automated hand-held device improves patient outcomes from in-hospital cardiac arrest (IHCA).We conducted prospective, randomized, controlled, parallel study (no crossover) of patients with IHCA in the mixed medical-surgical intensive care units (ICUs) eight academic hospitals. Patients received either standard manual chest compressions or performed Cardio First Angel™ (CFA) device. The primary outcome was sustained return spontaneous...
Hyperinflammatory state has a role in the pathogenesis of COVID-19. Anakinra could reduce inflammation and help to combat condition. In this study, we aimed assess safety efficacy anakinra (PerkinRA®) severe COVID-19.The study was an open-label, randomized, controlled trial conducted Imam Hossein Medical Center from May July 2020. Patients with confirmed diagnosis COVID-19 were included study. We administered 100 mg daily intravenously. All patients received pharmacotherapy based on...
Multiple trauma can cause an increase in creatine phosphokinase (CPK) and subsequently rhabdomyolysis acute kidney injury (AKI). This study was designed to evaluate the effect of vitamin D3 on serum CPK level incidence rhabdomyolysis-induced AKI patients with multiple trauma. Patients levels <1000 IU/L were followed as control 1 group. Subjects ≥1000 randomly allocated 2 or intervention group at Imam Hossein Medical Center, Tehran, Iran 2020. received a single dose (300,000 units)...
Background: It is known that in certain situations, such as heart failure, hypertonic saline can facilitate fluid removal by diuretics — especially loop which improve the pathophysiological condition and reduce symptoms hospitalized ICU patients. Objectives: Our study aimed to evaluate effect of adding 5% NaCl solution managing edema increasing urine volume critically ill patients with edema. Methods: This was designed a two-arm, parallel-group, randomized, open-label clinical trial blinded...
To determine if non-invasive oxygenation indices, namely peripheral capillary oxygen saturation (SpO2)/fraction of inspired (FiO2) and partial pressure alveolar (PAO2)/FiO2 may be used as effective surrogates for the arterial (PaO2)/FiO2. Also, to SpO2/FiO2 PAO2/FiO2 values that correspond PaO2/FiO2 thresholds identifying acute respiratory distress syndrome (ARDS) in patients following coronary artery bypass graft (CABG) surgery. A prospective derivation-validation cohort study Open-Heart...
In late December 2019, a cluster of unexplained pneumonia cases has been reported in Wuhan, China, named coronavirus disease 2019 (COVID -19) which spreading 204 countries. this review, the mains pharmaceutical option quoted previously and especially available for ICU patients are reviewed.
The purpose of this study was evaluating the efficacy and safety intravenous (IV) ampicillin-sulbactam plus nebulized colistin in treatment Ventilator-Associated Pneumonia (VAP) caused by MDR Acinetobacter (MDRA) ICU patients as an alternative to IV colistin. In single-blinded RCT, one group received another (16 12 from total 28 patients, respectively) for 14 days or since clinical response. Both groups mesh nebulizer. There were no statistically significant differences between 2 baseline...
The rapid shallow breathing index (RSBI) is used clinically to help predict a patient's likelihood of successful liberation from mechanical ventilation (MV). However, the traditional threshold (<105 breaths/min/L) may underperform in patients with chronic obstructive pulmonary disease (COPD). We sought determine optimal RSBI for COPD improve diagnostic accuracy predicting ventilator liberation.This was prospective observational multicenter study [according Global initiative Chronic...
Sepsis is one of the common causes hospitalization patients in intensive care units. A significant role for vitamin D sepsis has been proposed, which due to its active metabolite, calcitriol.
A Case of pregnant woman (G2Ab1, twin pregnancy with microinjection, Gestational Age 23 weeks and 3 days) referred to our center a complaints fever dry cough dyspnea. She was admitted diagnosis COVID-19. During the hospitalization, O2 saturation progressively decreased, which led patient get intubate. Gradual recovery treatment occurred extubed. Unfortunately, she intubated again due decreased saturation, 5 days later. Liver enzymes increased, then both fetuses died intrauterine, cardiac...