A5072985433- Health and Medical Studies
- Urinary Tract Infections Management
- Palliative Care and End-of-Life Issues
- Geriatric Care and Nursing Homes
- Urinary Bladder and Prostate Research
- Clinical practice guidelines implementation
- Frailty in Older Adults
- Antibiotic Use and Resistance
- Chronic Disease Management Strategies
- Health Systems, Economic Evaluations, Quality of Life
- Pediatric Urology and Nephrology Studies
- Childhood Cancer Survivors' Quality of Life
- Pelvic floor disorders treatments
- Emergency and Acute Care Studies
- Long-Term Effects of COVID-19
- Healthcare cost, quality, practices
- SARS-CoV-2 detection and testing
- Empathy and Medical Education
- Patient Dignity and Privacy
- COVID-19 and Mental Health
- COVID-19 Clinical Research Studies
- Social and Demographic Issues in Germany
- Sepsis Diagnosis and Treatment
- Clinical Laboratory Practices and Quality Control
- Patient-Provider Communication in Healthcare
Jena University Hospital
2019-2025
Friedrich Schiller University Jena
2022-2025
Medizinische Hochschule Hannover
2011-2021
LMU Klinikum
2020
<b>Study question</b> Can treatment of the symptoms uncomplicated urinary tract infection (UTI) with ibuprofen reduce rate antibiotic prescriptions without a significant increase in symptoms, recurrences, or complications? <b>Methods</b> Women aged 18-65 typical UTI and risk factors complications were recruited 42 German general practices randomly assigned to single dose fosfomycin 3 g (n=246; 243 analysed) 3×400 mg (n=248; 241 for three days (and respective placebo dummies both...
Abstract Background Uncomplicated lower urinary tract infections (UTI) are usually treated with antibiotics. However, there is little evidence for alternative therapeutic options. This pilot study was set out 1) to make a rough estimate of the equivalence ibuprofen and ciprofloxacin uncomplicated infection regard symptom resolution, 2) demonstrate feasibility double-blind, randomized controlled drug trial in German general practices. Methods We performed 29 Eighty otherwise healthy women...
Guideline recommendations on therapy in urinary tract infections are based antibiotic resistance rates. Due to a lack of surveillance data, little is known about rates uncomplicated infection (UTI) general practice Germany. In prospective observational study, urine cultures all women presenting with were analysed. Resistance against antibiotics recommended German guidelines UTI presented. prospective, multi-center study practitioner included female patients ≥ 18 years clinically suspected...
Heart failure (HF) is a life-limiting illness and patients with advanced heart often suffer from severe physical psychosocial symptoms. Particularly in older patients, HF occurs conjunction other chronic diseases, resulting complex co-morbidity. This study aims to understand how old very perceive their disease identify medical, information needs, focusing on the last phase of life. Qualitative longitudinal interview (≥70 years) (NYHA III-IV). Interviews were conducted at three-month...
Some patients experience long-term sequelae after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, despite a present post-COVID condition, defined as "any symptom lasting longer than 12 weeks," only subset of search for medical help and therapy.We invited all adults positive real-time polymerase chain reaction (RT-PCR) SARS-CoV-2 between March 2020 September 2021 (n = 4091) in the city Jena to answer standardized questionnaire including demographic...
Abstract Objectives To evaluate whether a multimodal intervention in general practice reduces the proportion of second line antibiotic prescriptions and overall for uncomplicated urinary tract infections women. Design Parallel, cluster randomised, controlled trial. Setting General practices five regions Germany. Data were collected between 1 April 2021 31 March 2022. Participants practitioners from 128 randomly assigned practices. Interventions Multimodal consisting guideline recommendations...
Uncomplicated urinary tract infections (UTI) are common in general practice, and usually treated with antibiotics. Recurrent UTI often pose a serious problem for affected women. Little is known about recurrent complications when uncomplicated without With ICUTI (Immediate vs. conditional antibiotic use UTI, funded by BMBF No. 01KG1105) we assessed whether initial symptomatic treatment ibuprofen could be alternative UTI. The presented analysis aims to assess the influence of (non-)antibiotic...
Frail older people are an increasingly important group in primary care due to demographic change. For these patients, a palliative approach may be useful sustain the quality of life last phase their lives. While general practitioners (GPs) play key role for is still its infancy and little known Germany about caring frail towards end life. This study aims explore tasks challenges regarding patients from GPs' point view, latter's perception own responsibilities.Explorative qualitative based on...
Abstract Background Uncomplicated urinary tract infections (UTI) are usually treated with antibiotics as recommended by primary care guidelines. Antibiotic treatment supports clinical cure in individual patients but also leads to emerging resistance rates the population. We designed a comparative effectiveness study investigate whether use of for uncomplicated UTI could be reduced initial ibuprofen, reserving antibiotic who return due ongoing or recurrent symptoms. Methods/design This is...
Uncomplicated urinary tract infections (UTI) are common in general practice and usually treated with antibiotics. This contributes to increasing resistance rates of uropathogenic bacteria. A previous trial showed a reduction antibiotic use women UTI by initial symptomatic treatment ibuprofen. However, this strategy is not suitable for all equally. Arctostaphylos uva-ursi (UU, bearberry extract arbutin) potential alternative treatment. study aims at investigating whether an UU can reduce...
Medication safety is an important health issue for nursing home residents (NHR). They usually experience polypharmacy and often take potentially inappropriate medications (PIM) antipsychotics. This, coupled with a frail state, makes NHR particularly vulnerable to adverse drug events (ADE). The value of systematic medication reviews interprofessional co-operation improving quality in has been recognized. Yet the evidence positive effect on NHR' wellbeing inconclusive at this stage. This study...
At the end of life, about 85-90% patients can be treated within primary palliative care (PC) provided by general practitioners (GPs). In Germany, there is no structured approach for provision PC GPs including a systematic as well timely identification who might benefit from PC, yet. The project "Optimal at life" (OPAL) focusses on an improvement with both oncological and non-oncological chronic progressive diseases in their last phase life health services.OPAL will take place Hameln-Pyrmont,...
Background/Objectives: Despite recent decades’ rapid advances in the management of patients with sepsis and septic shock, global mortality post-acute morbidity rates remain high. Our aim was, therefore, to provide a first overview care pathways as well barriers supportive conditions for optimal pre-clinical, clinical, Germany. Methods: Between May September 2023, we conducted semi-structured, video-based, one-to-one pilot expert interviews healthcare professionals representing pre-hospital,...
Physician-assisted suicide (PAS) has been legalised in an increasing number of countries Western Europe. In Germany, after a landmark decision by the Federal Constitutional Court 2020, ban on PAS was removed from Model Medical Code Conduct 2021. Although German Association makes it clear that assisted (AS) is not genuine medical task, doctors have approached about it. As long-standing, trusted companions their patients, general practitioners (GPs) can be predestined as initial contacts for...
Abstract Background Due to their fast turnaround time and user-friendliness, point-of-care tests (POCTs) possess a great potential in primary care. The purpose of the study was assess general practitioners’ (GPs) perspectives on POCT use German care, including utilization, limitations requirements. Methods We conducted cross-sectional survey among GPs Germany (federal states Thuringia, Bremen Bavaria (Lower Franconia), period: 04/22–06/2022). Results From 2,014 reached, 292 participated our...
Abstract Background General Practitioners (GPs) are the main providers of primary palliative care (PPC). At same time they initiators specialised homecare (SPHC). In Germany, little is known about factors which influence GPs in their involvement SPHC. Aim our study to identify that drive give value and involve Methods A cross-sectional survey was performed. 2018, questionnaires were mailed 6000 randomly selected from eight German federal states, focusing on extent GPs’ activities Results...
Patient and public involvement (PPI) has become an essential part of the design, conduct, dissemination research. While researchers who employed PPI mainly report on positive aspects, in practice is still exception clinical trials Germany. There are specific challenges process that can jeopardize conduct involvement. The aim our study was to analyze experience patients with a trial Germany, so we could learn more about potential how they be addressed.We established patient board for...