Barbora de Courten
A5073815544- Biochemical effects in animals
- Diet and metabolism studies
- Stress Responses and Cortisol
- Vitamin D Research Studies
- Free Radicals and Antioxidants
- Nutritional Studies and Diet
- Ovarian function and disorders
- Diet, Metabolism, and Disease
- Adipokines, Inflammation, and Metabolic Diseases
- Advanced Glycation End Products research
- Global Public Health Policies and Epidemiology
- Obesity, Physical Activity, Diet
- Human Health and Disease
- Adipose Tissue and Metabolism
- Eating Disorders and Behaviors
- Nutrition and Health in Aging
- Liver Disease Diagnosis and Treatment
- Global Health Care Issues
- Health Systems, Economic Evaluations, Quality of Life
- Vitamin C and Antioxidants Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health disparities and outcomes
- Pancreatic function and diabetes
- Metabolism, Diabetes, and Cancer
- Global Maternal and Child Health
Monash University
2016-2025
Monash Health
2016-2025
RMIT University
2022-2025
The University of Queensland
2024
Australian Regenerative Medicine Institute
2017-2023
University of Washington
2018-2022
Institute for Health Metrics and Evaluation
2017-2022
The Alfred Hospital
2021
Republic of Burundi
2020
UNSW Sydney
2019
Stroke is a leading cause of mortality and disability worldwide the economic costs treatment post-stroke care are substantial. The Global Burden Diseases, Injuries, Risk Factors Study (GBD) provides systematic, comparable method quantifying health loss by disease, age, sex, year, location to provide information systems policy makers on more than 300 causes disease injury, including stroke. results presented here estimates burden due overall stroke ischaemic haemorrhagic from GBD 2016.
<h2>Summary</h2><h3>Background</h3> Previous attempts to characterise the burden of chronic respiratory diseases have focused only on specific disease conditions, such as obstructive pulmonary (COPD) or asthma. In this study, we aimed globally, providing a comprehensive and up-to-date analysis geographical time trends from 1990 2017. <h3>Methods</h3> Using data Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2017, estimated prevalence, morbidity, mortality attributable through an...
<h2>Summary</h2><h3>Background</h3> Cirrhosis and other chronic liver diseases (collectively referred to as cirrhosis in this paper) are a major cause of morbidity mortality globally, although the burden underlying causes differ across locations demographic groups. We report on results from Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2017 its trends since 1990, by cause, sex, age, for 195 countries territories. <h3>Methods</h3> used data vital registrations, registration...
Background— Low plasma high-density lipoprotein (HDL) is associated with elevated cardiovascular risk and aspects of the metabolic syndrome. We hypothesized that HDL modulates glucose metabolism via elevation insulin through activation key regulatory enzyme, AMP-activated protein kinase, in skeletal muscle. Methods Results— Thirteen patients type 2 diabetes mellitus received both intravenous reconstituted (rHDL: 80 mg/kg over 4 hours) placebo on separate days a double-blind,...
A comprehensive understanding of temporal trends in the disease burden Australia is lacking, and these are required to inform health service planning improve population health. We explored diseases their risk factors from 1990 2019 through a analysis Global Burden Disease Study (GBD) 2019.In this systematic for GBD 2019, we estimated all-cause mortality using standardised methodology. Data sources included primarily vital registration systems with additional data sample registrations,...
Objective Carnosine is a naturally present dipeptide in humans and an over‐the counter food additive. Evidence from animal studies supports the role for carnosine prevention treatment of diabetes cardiovascular disease, yet there limited human data. This study investigated whether supplementation individuals with overweight or obesity improves risk factors. Methods In double‐blind randomized pilot trial nondiabetic (age 43 ± 8 years; body mass index 31 4 kg/m 2 ), 15 were randomly assigned...
Insulin resistance, hyperandrogenism, sympathetic dysfunction and chronic low-grade inflammation may act together in a vicious cycle the pathophysiology of PCOS. However, inter-relationships these components are not fully understood. We aimed to study mechanisms PCOS.Premenopausal women with PCOS (Rotterdam diagnostic criteria) without were recruited from community setting into cross-sectional substudy within randomized control trial. resistance (fasting insulin glucose), hyperandrogenism...
OBJECTIVE High-heat cooking of food induces the formation advanced glycation end products (AGEs), which are thought to impair glucose metabolism in type 2 diabetic patients. High intake fructose might additionally affect endogenous AGEs. This parallel intervention study investigated whether addition or methods influencing AGE content insulin sensitivity overweight individuals. RESEARCH DESIGN AND METHODS Seventy-four women were randomized follow either a high- low-AGE diet for 4 weeks,...
OBJECTIVE The goal of this study was to determine whether plasma levels advanced glycation end products (AGE) and oxidation (OP) predict the incidence cardiovascular disease (CVD) in type 2 diabetes. RESEARCH DESIGN AND METHODS Five specific AGE (methylglyoxal hydroimidazolone, carboxymethyl lysine, carboxyethyl 3-deoxyglucosone glyoxal hydroimidazolone) two OP (2-aminoadipic acid methionine sulfoxide [MetSO]) were measured at baseline intensive glucose-lowering studies: 1) a subcohort...
This study explores the prevalence of, and factors associated with, likely depression diabetes distress in adults with type 2 a large, national sample. Australian National Diabetes Audit data were analysed from attending 50 centres. The Brief Case find for Depression Distress Score 17 administered to screen diabetes-related distress, respectively. A total of 2,552 participated: (mean ± SD) age was 63 13 years, duration 12 10 HbA1c 8 2%. Twenty-nine percent patients had depression, 7% high 5%...