Antônio Sérgio Costa Carvalho

ORCID: 0000-0001-8810-141X
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About
Contact & Profiles
Research Areas
  • Biochemical Analysis and Sensing Techniques
  • Dye analysis and toxicity
  • melanin and skin pigmentation
  • Agricultural and Food Sciences
  • Polysaccharides and Plant Cell Walls
  • Cardiac Valve Diseases and Treatments
  • Streptococcal Infections and Treatments
  • Fungal Biology and Applications
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Insect and Pesticide Research
  • Toxin Mechanisms and Immunotoxins
  • Hops Chemistry and Applications
  • Enzyme Catalysis and Immobilization
  • Research on Leishmaniasis Studies
  • Biochemical and Structural Characterization
  • Environmental Sustainability and Education
  • Phytochemistry Medicinal Plant Applications
  • Cellular Mechanics and Interactions
  • Skin Protection and Aging
  • Enzyme Production and Characterization
  • Infective Endocarditis Diagnosis and Management

Universidade Federal do Pará
2012-2024

Amazon (Germany)
2023

Amazon (United States)
2023

Amazon Research Foundation
2023

Associação Brasileira da Batata
2023

IberEspacio (Spain)
2023

Vetenskap I Skolan
2023

Hospital La Luz
2023

Natura (Brazil)
2014

Secretaria de Planejamento e Gestão
2010

Kojic acid (KA) is a fungal metabolite used as topical treatment skin-whitening cosmetic agent for melasma in humans; however its potential an anti-leishmanial unknown. Chemotherapy one of the most effective treatments Leishmaniasis. However, drugs available are expensive, invasive, require long-term and have severe side effects. Thus, development new leishmanicidal agents necessity. In this study we investigated effect KA on L. amazonensis, following vitro vivo infections. (50 μg/mL) was...

10.1371/journal.pone.0091259 article EN cc-by PLoS ONE 2014-03-12

KA (kojic acid) is a secondary metabolite isolated from Aspergillus fungi that has demonstrated skin whitening, antioxidant and antitumour properties among others. However, limited information available regarding its effects on macrophages, the major cell involved in defence. The aim of present study was to analyse whether affects functional related macrophage activation, such as phagocytosis spreading ability over substrate. Treatment resident macrophages with 50 μg/ml for 1 h induced both...

10.1042/cbi20100083 article EN Cell Biology International 2010-11-03

In the present study, 5-Hydroxy-2-(Oleoyloxymethyl) -4H-pyran-4-one (KMO 3), and their chelated with Cu(II) Fe(III) ions were synthesized to explore inhibitory activity against tyrosinase cytotoxicity. To this end, structures of obtained compounds confirmed by ATR/FT-IR, 13C 1H-NMR, UV-vis techniques. The results show that chelating fatty ester presents bands at 1567m, 1511w cm-1 attributed coordinated carbonyl (Cu(II)←[O=C]2), 1540m, 1519m which (Fe(III)←[O=C]3). effect Oleic acid 2...

10.1590/0001-3765202420240668 article EN cc-by Anais da Academia Brasileira de Ciências 2024-01-01

ml, uma atividade total de 317,5U e enzimática especifica 0,276U/µg.CONCLUSÃO: Concluiuse que a razão 1g enzima para 5ml tampão foi melhor se extrair enzima, haja vista os resultados foram superiores.A fibra do coco, apresentou rendimento 91% depois um pré tratamento com hidróxido sódio.O paracetamol extraído apresentando 85%.Dessa forma, realizou biotransformação acetaminofeno comprovada análise UV-VIS, onde formou-se o bioproduto no comprimento onda 340nm.A perspectiva trabalhos futuros é...

10.51189/iii-conbiotec/16727 article PT 2023-03-28

Complex bis (2-Oleicoyloxymethyl-5-hydroxy-gamma-pyrone) copper (II) and tris iron (III) were prepared in ethanol using the structure chelator conjugate kojic -lipid. This ester was obtained from acid by improving their lipophilicity of obtaining metalobioactives with application Medicinal Bioinorganic Chemistry. Through technique ATR/FTIR, values ​​ infrared has been updated it possible to characterize      the complex 1567m, 1511w (Cu ← [O=C] 2 ), 1540m, 1519m (Fe(III) 3 . These compounds...

10.17807/orbital.v4i1.335 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2012-06-01
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