A5101558800- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Risk Factors
- Cardiovascular Health and Disease Prevention
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Sodium Intake and Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Heart Rate Variability and Autonomic Control
- Birth, Development, and Health
- Lipoproteins and Cardiovascular Health
- Cardiovascular Disease and Adiposity
- Sleep and related disorders
- Cancer, Lipids, and Metabolism
- Ubiquitin and proteasome pathways
- Chronic Kidney Disease and Diabetes
- Folate and B Vitamins Research
- Gout, Hyperuricemia, Uric Acid
- Sleep and Work-Related Fatigue
- S100 Proteins and Annexins
- Antiplatelet Therapy and Cardiovascular Diseases
- Ferroptosis and cancer prognosis
- Advanced Glycation End Products research
China Medical University
2014-2024
First Hospital of China Medical University
2012-2024
Shanghai East Hospital
2023
Health Commission of Jilin Province
2021
First Hospital of Lanzhou University
2018
Lanzhou University
2018
Chinese PLA General Hospital
2013-2017
Tongji University
2008-2015
Hainan Branch of People's Liberation Army General Hospital
2015
Creative Commons
2015
Background and Purpose— Information has been sparse on the comparison of pulse pressure (PP) mean arterial (MAP) in relation to ischemic stroke among patients with uncontrolled hypertension. The present study examined PP, MAP, hypertensive subjects China. Methods— A total 6104 aged ≥35 years were screened a stratified cluster multistage sampling scheme Fuxin county Liaoning province China, which 317 had stroke. Results— After multivariable adjustment for age, gender, other confounders,...
Ischemia-reperfusion (I/R) injury is believed to be the major cause for detriments in coronary heart diseases, but few effective therapies prevention or treatment of I/R are available. Gypenoside (GP) predominant component Gynostemma pentaphyllum and possesses capacities against inflammation oxidation. In present study, role GP ameliorating myocardial was investigated.effect on cardiac structure injured rats assessed by H&E TTC staining. Then influence function rat model determined...
Gypenosides (GP) are the predominant components of Gynostemma pentaphyllum, a Chinese herb medicine that has been widely used for treatment chronic inflammation, hyperlipidemia, and cardiovascular disease. GP demonstrated to exert protective effects on liver brain against ischemia-reperfusion (I/R) injury, yet whether it is beneficial heart during myocardial I/R unclear. In this study, we demonstrate pre-treatment with dose-dependently limits infarct size, alleviates I/R-induced pathological...
Abstract Background: Short sleep duration was reported to be associated with an increased risk of hypertension among adults. The present study aimed investigate this association in children and adolescents. Hypothesis: is related higher Methods: We conducted a cross‐sectional 4902 adolescents age 5 18 years. Blood pressure (BP) measured at the research center classified using population‐based percentiles. Sleep information were determined through questionnaires. Results: prevalence...
Abstract Background Endothelial injury caused by Type 2 diabetes mellitus (T2DM) is considered as a mainstay in the pathophysiology of diabetic vascular complications (DVCs). However, molecular mechanism T2DM-induced endothelial remains largely unknown. Here, we found that WW domain-containing E3 ubiquitin protein ligase (WWP2) act novel regulator for through modulating ubiquitination and degradation DEAD-box helicase 3 X-linked (DDX3X). Methods Single-cell transcriptome analysis was used to...
Abstract Background and Objectives Cardiac injury plays a critical role in contributing to the mortality associated with sepsis, condition marked by various forms of programmed cell deaths. Previous studies hinted at WW domain-containing E3 ubiquitin protein ligase 2 (WWP2) involving heart failure endothelial injury. However, precise implications WWP2 sepsis-induced cardiac injury, along underlying mechanisms, remain enigmatic. Methods Sepsis induced were constructed intraperitoneal...
The objective of this study was to estimate the prevalence prehypertension and hypertension in rural adults Liaoning province China.
<b>OBJECTIVE</b> We wanted to determine the incidence of hypertension and its risk factors among rural Chinese adults. <b>METHODS</b> A population-based sample 24,360 adults aged 35 years older free from at baseline was observed 2004–2006 2008. Incident defined as a systolic pressure 140 mm Hg or greater, diastolic 90 current use antihypertensive medication. <b>RESULTS</b> During mean follow-up period 28 months, 29.6% men 23.4% women developed hypertension. The age-adjusted higher in (12.75...
Abstract Background Pediatric obesity has become a global public health problem. Data on the lifestyle behaviors, dietary habits, and familial factors of overweight obese children adolescents are limited. The present study aims to compare health-related among normal-weight, overweight, Chinese adolescents. Methods We conducted cross-sectional consisted 4262 aged 5–18 years old from rural areas northeast China. Anthropometric measurements self-reported information variables, such as physical...
Background: Overweight and obesity are now considered as a serious health problem, very important risk factor for many diseases. Objective: This study was designed to investigate the epidemiologic features of overweight among rural adults in China. Method Procedures: A cross‐sectional survey conducted during 2004–2005, using multistage cluster sampling method select representative sample Fuxin county, Liaoning province, total 29,970 adults, aged ≥35 years, were examined. At baseline,...
Individuals with prehypertension are at a high risk of developing hypertension. Little is known about the predictors progression from prehypertesion to hypertension in rural Chinese adults.A population-based sample 15 061 aged > or =35 years free cardiovascular diseases baseline were followed-up 2004-2006 2008. Incident was defined as systolic blood pressure (BP) =140 mmHg, diastolic BP =90 current use antihypertensive medications.During 28-month follow-up period, 4917 individuals (32.6%)...
Elevated alanine aminotransferase (ALT) levels may be associated with metabolic syndrome and cardiovascular diseases. This study aimed to investigate the association between elevated ALT cardiometabolic risk factors in a rural Chinese population. was cross-sectional conducted from July 2012 August 2013, including 11,573 subjects (5,357 men 6,216 women) aged ≥35 years areas of Liaoning Province. A physical examination performed indicators were examined under standard protocols. Subjects...
Background Prehypertension is a new category of blood pressure (BP) classification according to the Seventh Report The Joint National Committee. Little known about epidemiology prehypertension in rural China. purpose present study determine prevalence and associated risk factors adult people Methods Results Through cluster multistage random sampling method, resident group 29,970 aged ≥35 years old Liaoning Province was selected from 2004 2005. survey on BP carried out. defined as systolic...
Background To evaluate the status of overweight and obesity in a Chinese rural adult population describe relationships between body mass index (BMI) blood pressure according to JNC-7. Methods The study was conducted 2004-2006, used multistage cluster sampling method select representative sample. A total 45,925 adults, age 35 years or older, were examined. Height, weight obtained by trained doctors. Overweight defined World Health Organization classification definition. Results prevalence...