A5100371654- Nutrition and Health in Aging
- Blood Pressure and Hypertension Studies
- Frailty in Older Adults
- Renal Diseases and Glomerulopathies
- Body Composition Measurement Techniques
- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Parathyroid Disorders and Treatments
- Cardiovascular Health and Disease Prevention
- Cardiac Health and Mental Health
- Lymphoma Diagnosis and Treatment
- Clinical Nutrition and Gastroenterology
- Balance, Gait, and Falls Prevention
- Gastric Cancer Management and Outcomes
- GDF15 and Related Biomarkers
- Colorectal Cancer Treatments and Studies
- Viral-associated cancers and disorders
- Cardiovascular Function and Risk Factors
- Chronic Lymphocytic Leukemia Research
- Cardiovascular Health and Risk Factors
- Occupational and environmental lung diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Enhanced Recovery After Surgery
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Hepatocellular Carcinoma Treatment and Prognosis
China Medical University
2020-2025
Second Xiangya Hospital of Central South University
2017-2025
Central South University
2017-2025
First Hospital of China Medical University
2020-2025
Hong Kong Jockey Club
2025
Chinese University of Hong Kong
2025
Harbin Medical University
2021-2024
National Health and Family Planning Commission
2024
Guangzhou Center for Disease Control and Prevention
2023-2024
First Hospital of Jilin University
2018-2024
The assessment of nutritional status and the quality life in patients with gastric cancer has become one important goals current clinical treatment. purpose this study was to assess hospitalized by using patient-generated subjective global (PG-SGA) analyze influence on patients' (QOL). We reviewed pathological diagnosis for 2322 PG-SGA their collected data symptoms, anthropometric parameters (height, weight, body mass index (BMI), mid-arm circumference (MAC), triceps skin-fold thickness...
Roxadustat, a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor, promotes erythropoiesis and regulates iron metabolism. This study investigated the efficacy safety of roxadustat in Chinese patients with anemia on peritoneal dialysis (PD). One hundred twenty-nine were randomized treated (n = 86) or erythropoiesis-stimulating agents (ESAs) 43) for 24 weeks. The primary end points mean hemoglobin (Hb) level at week 24, change average Hb levels from baseline to cumulative...
The newly proposed Global Leadership Initiative on Malnutrition (GLIM) framework is promising to gain global acceptance for diagnosing malnutrition. However, the role of machine learning in facilitating its application clinical practice remains largely unknown.We performed a multicenter, observational cohort study including 3998 patients with cancer. Baseline malnutrition was defined using GLIM criteria, and population randomly divided into derivation group (n = 2998) validation 1000). A...
Abstract Background 5‐Fluorouracil (5‐FU) and capecitabine‐associated cardiotoxicity ranging from asymptomatic electrocardiography (ECG) abnormalities to severe myocardial infarction has been reported in a number of studies, but such Chinese patients with malignant diseases not investigated date. In the present study, we aimed prospectively evaluate incidence rates clinical manifestations 5‐FU‐ cancer recruited multiple centers China. Methods Among 527 who completed 196 received 5‐FU‐based...
Background Cancer cachexia is a complex metabolic syndrome characterised by loss of muscle with or without fat mass, and associated high morbidity mortality. Despite its clinical importance, there lack simple tools to screen patients for cancer cachexia. The aim this study was evaluate validate the patient-generated subjective global assessment (PG-SGA) as screening tool Methods This secondary analysis multicentre, cross-sectional, observational study. diagnosed when weight ≥5% during past...
As a developing country with the largest older adult population in world, strengthening research on falls among adults is undoubtedly an urgent item China. This study aimed to explore prevalence and risk factors associated injury from community-dwelling Guangzhou, China, particularly focusing their associations chronic diseases.A total of 1,629 participants aged 65 years above were selected 11 counties Guangzhou by multi-stage stratified random sampling method 2021. Socio-demographic...
<title>Abstract</title> Background and hypothesis. Vascular calcification (VC) is an important risk factor for cardiovascular events in patients undergoing maintenance hemodialysis (MHD); however, there limited data on VC-related factors beginning hemodialysis. Thus, this study aimed to determine the of VC establish a prediction model evaluating progression new Methods. This selected 86 who initiated in-center MHD between March 2021 November 2022. Demographic characteristics, medical...
Background Blood pressure (BP) management in patients with metabolic syndrome is complex, and optimal targets remain debated. The CRHCP (China Rural Hypertension Control Project) trial demonstrated that intensive BP control reduces cardiovascular events. This secondary analysis assessed its efficacy hypertension syndrome. Methods Results a post hoc of cluster randomized (NCT03527719) across 3 Chinese provinces; 18 076 hypertensive were followed up for years. Intervention groups received...
Vascular calcification (VC) is an important risk factor for cardiovascular events in patients undergoing maintenance hemodialysis (MHD); however, there limited data on VC-related factors beginning hemodialysis. Thus, this study aimed to determine the of VC and establish a prediction model evaluating progression new This selected 86 who initiated in-center MHD between March 2021 November 2022. Demographic characteristics, medical history, laboratory were collected. Coronary artery (CAC) was...
Abstract IMPORTANCE MM was an incurable clonal plasma cell malignancy with substantial prevalence and incidence, which had resulted in a significant burden of disease. Our study aimed to evaluate the global, regional national by sex, age, SDI from 1990 2021, along associated risk factors predicted temporal trends. OBJECTIVE To assess global burden, epidemiological trends, project its incidence rate 2050. Design This is systematic analysis 2021. Setting The primarily analyzed prevalence,...
Background: Psychological flexibility is the concept and focus of Acceptance Commitment Therapy. It has been demonstrated to benefit self-efficacy depressive symptoms. However, its role in diabetes self-management (DSM) potential mechanisms remain unknown. Purpose: This study aimed investigate association between psychological explore mediating effect symptoms among people with China. Methods: Using a cross-sectional design, 249 type 2 China were recruited from February 1, 2024, April 30,...
Abstract The present study evaluated whether fat mass assessment using the triceps skinfold (TSF) thickness provides additional prognostic value to Global Leadership Initiative on Malnutrition (GLIM) framework in patients with lung cancer (LC). We performed an observational cohort including 2672 LC China. Comprehensive demographic, disease and nutritional characteristics were collected. was retrospectively defined GLIM criteria, optimal stratification used determine best thresholds for TSF....
To investigate the relationship between atherogenic index of plasma (AIP) and ischemic stroke.We collected a range data from 11,495 residents (aged ≥35 years; 54.28% female) residing in rural areas northeast China January August 2013, including fasting lipid profile anthropometric parameters. Logistic regression models were used to evaluate correlation AIP stroke. Category-free analysis was determine whether enhanced our capacity estimate stroke.Irrespective gender, independently associated...
Abstract Aims High systolic blood pressure (HSBP), a significant public health challenge, has not been systematically studied in the elderly population context of global aging. Understanding temporal trends disease burden associated with HSBP is essential to control and mitigate harm caused by HSBP. Methods results We used estimated data derived from Global Burden Disease Study analyse among region, sex, changes 1990 2019. found that number deaths due increased 7.86 (95% UI: 6.89–8.82)...
Abstract Purpose To investigate the frailty status in Chinese cancer patients through establishing a novel prediction algorithm. Methods The percentage of various age groups, locations, and tumor types was investigated. capacity on mortality analysed by index composing routine laboratory data (FI‐LAB) accessible from blood test calculated as ratio abnormal factors to 22 total variables. establishment algorithm, MCP (mortality patients), predict 5‐year accomplished algorithm's tested training...
Abstract Background The fat mass and nutritional status play important roles in the onset progression of cancer cachexia. present study evaluated joint prognostic value mass, as indicated by triceps skinfold thickness (TSF), serum albumin level, for mortality patients with Methods We performed a multicentre cohort including 5134 cachexia from January 2013 to April 2019. sum TSF (mm) (g/L) was defined skinfold–albumin index (TA). Harrell's C index, time‐dependent receiver operating...
Abstract Background The 2018/2023 ESC/ESH Guidelines underlined a gap how baseline cardiovascular disease (CVD) risk predicted blood pressure (BP) lowering benefits. Further, 2017 ACC/AHA Guideline and 2021 WHO recommended implementation studies about intensive BP control. Now, to bridge these guideline gaps, we conducted post hoc analysis validate whether the CVD influences effectiveness of control strategy, which was designed by China Rural Hypertension Control Project (CRHCP). Methods...