Abstract Background: The aim of the present study was to investigate effect different doses vitamin C on oxidative liver injury due isoniazid (INH) in rats. Methods: Rats were divided into four subgroups, each containing 10 Group 1 control group; group 2, INH 50 mg/kg per day; 3, day + low‐dose (100 day); 4, high‐dose (1000 day). and administered their stomachs through an oral tube. After 21 days, measurements made both serum homogenized tissues. levels glutathione (GSH), superoxide...

The features of pediatric patients with postoperative transient and permanent complete atrioventricular (AV) block (CAVB) were compared.Patients who developed CAVB in period after congenital cardiac surgery between 2010-2015 included the study. They classified as CAVB. demographics perioperative variables groups evaluated.A total 1,550 underwent during study period. was determined 96 (6.2%) early period: 66 had CAVB, 30 that necessitated pacemaker implantation. median body weight age at...

Junctional ectopic tachycardia (JET) is a rare form of arrhythmia that most commonly seen during infancy. JET continuous and incessant, characterized by persistently high heart rates may result in impaired cardiac function tachycardia-induced cardiomyopathy. Despite the availability multiple antiarrhythmic treatments, including flecainide amiodarone, management generally very difficult. Catheter ablation has risk atrioventricular block it require placement pacemaker. Ivabradine, also known...

Vascular rings may cause pressure on the trachea and/or esophagus of varying degree, resulting in symptoms. This study assessed presentation symptoms, diagnostic methods and treatment results after surgery children with vascular ring.Symptomatic ring patients undergoing between January 2010 August 2014 at Mehmet Akif Ersoy Cardiovascular Research Training Hospital, Istanbul, were retrospectively assessed. The demographic characteristics, tests evaluated. Operative data postoperative follow...

The aim of this study was to comprehensively evaluate electrocardiographic (ECG) findings isolated left ventricular noncompaction (IVNC) patients at initial diagnosis and explore the correlation between them clinical, echocardiographic, magnetic resonance imaging (MRI) findings.Twenty-three diagnosed with IVNC by echocardiography cardiac MRI January 2006 June 2010 were enrolled in study. examined standard ECG 24-hour Holter ECG. For comparison purpose, ECGs 50 healthy children similar ages...

Dexmedetomidine (DEX) is a highly selective alpha-2-adrenergic agonist approved for short-term sedation and monitored anesthesia care in adults. Its effects on the electrocardiography cardiac conduction tissue are not well described literature. Therefore, we aimed to characterize electrocardiographic electrophysiologic of DEX children.Twenty children (11 boys nine girls) between ages eight 17 undergoing electrophysiology study ablation supraventricular tachycardia had hemodynamic variables...

We evaluated the preoperative, operative and postoperative risk factors affecting early mortality in patients who underwent total correction of tetralogy Fallot (TOF).One hundred twenty-two TOF reparative surgery between January 2010 November 2013 were enrolled study.Mean patient age weight was 2.3 ± 2.5 years 11.3 6.4 kg, respectively. Cardiac catheterization performed 101 (83%),and coronary anomalies found 11 patients. Mean McGoon index, pulmonary annulus z-score, main artery left z-score...

The most common pediatric arrhythmias are tachycardias, and the type is supraventricular tachycardia, originating from or above atrioventricular node HIS bundle. Ventricular tachycardias less but more dangerous. Supraventricular usually cause a narrow complex tachycardia unless there basal bundle branch block rate-dependent aberration. A wide QRS should be treated as ventricular proven to an with Diagnosis of both tachyarrhythmia types depends mainly on 12-lead electrocardiography. in...

Background Epicardial implantation of implantable cardioverter defibrillators (ICDs) is considered in the presence intracardiac shunt, venous access issue, or small body size. We report our experience with epicardial ICD coil using a minimally invasive method. Methods Nine patients who underwent were included. The median age was 7.4 years (3.9–9.6 years) and weight 15 kg (12–24 kg). Diagnosis at time included long QT syndrome (n = 5), catecholaminergic polymorphic ventricular tachycardia 2),...

Curative therapy of idiopathic ventricular tachycardia remains a challenge in interventional electrophysiology. The aim this study was to demonstrate the utility an EnSite NavX system catheter ablation children.In all, 17 children with underwent electrophysiological studies using guidance.The mean patient age 13 ± 2.4 years (range: 7.8-17.9) and weight 52.3 11.9 kg 32-75). origin right outflow tract nine patients, left ventricle six, near bundle His/right branch one, aortic cusp one....

Introduction: Extracorporeal membrane oxygenation (ECMO) has become a standard technique over the past few decades in intensive care unit (ICU).Objective: A review of pediatric patients who received ECMO support cardiac ICU was conducted to determine incidence, risk factors and causal organisms related acquired infections assess survival rates with nosocomial infections.Methods: Sixty-six between January 2011 June 2014 were included study.Demographic, echocardiographic, hemodynamic features...

This study aims to evaluate early postoperative arrhythmias in children undergoing congenital cardiac surgery.A total of 670 pediatric patients (355 males, 315 females; median age: 4 months; range, 1 day 18 years) who underwent surgery due heart defects between December 2018 and November 2019 were included. The rate arrhythmias, diagnosis, potential risk factors, management strategies evaluated. Multivariate regression analysis was used identify significant factors development...

Isolated complete atrioventricular block is a rare disease often associated with maternal autoantibodies. This study aimed to present the midterm data of patients at our clinic diagnosed isolated block.We evaluated 108 block. Demographic patients, electrocardiography, echocardiography, 24-hour Holter monitoring data, and follow-up complications who underwent pacemaker implantation were retrospectively.The mean age diagnosis was 5.51 ± 5.05 years. At time diagnosis, 74.8% had no symptoms The...

Abstract Introduction Although amiodarone is traditionally used in the treatment of postoperative junctional ectopic tachycardia (JET), search for new treatments ongoing. We present our experience with ivabradine at two medical centers. Materials and Methods Between January 2022 2023, patients who developed JET after pediatric cardiac surgery were prospectively followed up documented. The diagnosis was made support electrophysiology team based primarily on whether disrupted hemodynamics....

Aim We evaluated ambulatory patients with Duchenne muscular dystrophy from the cardiovascular standpoint and studied correlation between results of electrocardiographic (ECG) findings, left ventricular ejection fraction (LVEF), troponin T N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) levels patients' North Star Ambulatory Assessment scores. Methods: Fifty ages 6–12 (8.9 ± 2.8) were enrolled in this cross‐sectional study. Cardiac evaluation included electrocardiography,...

Abstract Background The aim of this study was to examine the causes cardiac tamponade in children undergoing percutaneous pericardiocentesis. Method Patients who presented with other complaints but were diagnosed based on clinical and echocardiographic findings between J anuary 2010 2013 retrospectively investigated. Electrocardiography, telecardiography transthoracic echocardiography performed. Pericardiocentesis performed percutaneously under continuous blood pressure rhythm monitoring...

We report the case of a 2.5 month-old infant with cyanotic breath-holding spells, loss consciousness and seizures. Prolonged asystole up to 70 s despite cardiopulmonary resuscitation was documented by 24 hour Holter monitoring. An epicardial pacemaker implanted followed no further seizures during spells in six month follow-up period.

The aim of this study was to evaluate the indications, results and complications radiofrequency ablation (RFA) transcatheter cryoablation (TCA) in neonates infants with incessant drug-resistant supraventricular tachycardia (SVT).Out 225 patients who underwent RFA TCA at our center between January2010 February 2012, 5 under age 1 (4 male, female) were evaluated. indication for RFA/TCA recurrent hemodynamically compromising SVT.Over a 2-year period, 6 procedures performed patients. Average...

Syncope is a frequent complaint in children and adolescents may be significant sign of serious pathology. Although patient history, family physical examination are sufficient to reach diagnosis most cases syncope, the cause syncope still cannot determined after initial investigation one-third half all patients. The aim this study was evaluate diagnostic yield implantable loop recorder (ILR) with unexplained syncope.A retrospective review carried out clinical data, indications, findings,...

Objective: We evaluated autonomic behavior by examining heart rate variability (HRV) in the time domain and frequency pediatric patients who underwent transcatheter closure of atrial septal defect (ASD).Methods: A prospective study design was used.Holter ECG performed a control group 30 healthy subjects 47 ASD closure.ECG taken one day before, after, six months after procedure to evaluate changes [SDNN, rMSSD, NN, pNN50(%), SDANN] (VLF, LF, HF, VHF, LF/HF) patient group.Student's t-test used...