- Esophageal Cancer Research and Treatment
- Pelvic floor disorders treatments
- Prostate Cancer Diagnosis and Treatment
- Urinary Bladder and Prostate Research
- Neonatal and fetal brain pathology
- Stress and Burnout Research
- Global Health Care Issues
- Healthcare Policy and Management
- Colorectal Cancer Surgical Treatments
- Delphi Technique in Research
- Digital Imaging in Medicine
- Cerebrospinal fluid and hydrocephalus
- Health Systems, Economic Evaluations, Quality of Life
- Fetal and Pediatric Neurological Disorders
- Workplace Health and Well-being
- Resilience and Mental Health
- Gastric Cancer Management and Outcomes
University of Bristol
2015-2020
Background Localised oesophageal cancer can be curatively treated with surgery (oesophagectomy) but the procedure is complex a risk of complications, negative effects on quality life and recovery period 6–9 months. Minimal-access may accelerate recovery. Objectives The ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) study aimed to establish feasibility of, methodology for, definitive trial comparing minimally invasive open for oesophagectomy. were quantify number eligible...
Background The drainage, irrigation and fibrinolytic therapy (DRIFT) trial, conducted in 2003–6, showed a reduced rate of death or severe disability at 2 years the DRIFT compared with standard treatment group, among preterm infants intraventricular haemorrhage (IVH) post-haemorrhagic ventricular dilatation. Objectives To compare cognitive function, visual sensorimotor ability, emotional well-being, use specialist health/rehabilitative educational services, neuroimaging, economic costs...
BackgroundTransurethral resection of the prostate (TURP) is standard operation for benign prostatic obstruction. Thulium laser transurethral vaporesection (ThuVARP) a technique with suggested advantages over TURP, including reduced complications and hospital stay. We aimed to investigate TURP versus ThuVARP in men lower urinary tract symptoms or retention secondary obstruction.MethodsIn this randomised, blinded, parallel-group, pragmatic equivalence trial, seven UK hospitals bothersome...
Teachers are reported to be at increased risk of common mental health disorders compared other occupations. Failure support teachers adequately may lead serious long-term disorders, poor performance work (presenteeism), sickness absence and health-related exit from the profession. It also jeopardises student health, as distressed staff struggle develop supportive relationships with students, such protective against depression. A number school-based trials have attempted improve but these...
Background Transurethral resection of the prostate (TURP) is standard operation for benign prostatic obstruction (BPO). Thulium laser transurethral vaporesection (ThuVARP) vaporises and resects using a technique similar to TURP. The small amount existing literature suggests that there may be potential advantages ThuVARP over Objective To determine whether or not outcomes from are equivalent TURP in men with BPO treated NHS. Design A multicentre, pragmatic, randomised controlled...
Background Missing cost and outcomes data is a common problem for health economists analysing RCTs. Systematic reviews of the economic evaluation literature suggest that many analysts use crude methods (e.g. complete case analysis or single imputation) which are vulnerable to bias may underestimate uncertainty. Multiple imputation (MI) more appropriate if missing at random, but raises number methodological practical challenges. Two study RCTs assessing costeffectiveness new interventions...
You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology II (PD10)1 Apr 2019PD10-08 THULIUM LASER TRANSURETHRAL VAPORESECTION OF THE PROSTATE VERSUS RESECTION PROSTATE: RESULTS UNBLOCS RANDOMIZED CONTROLLED TRIAL Hashim Hashim, J Athene Lane*, Jo Worthington, Hilary Taylor, Grace Young, Sian Noble, Paul Abrams, Aideen Ahern, Sara Brookes, Nikki Cotterill, Lyndsey Johnson, Rafiyah Khan, Aida Moure Fernandez, Tobias Page, and Satchi Swami HashimHashim...