A5075233202- Pituitary Gland Disorders and Treatments
- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Bone Tumor Diagnosis and Treatments
- Adrenal and Paraganglionic Tumors
- Growth Hormone and Insulin-like Growth Factors
- Surgical Simulation and Training
- Anatomy and Medical Technology
- Sinusitis and nasal conditions
- Spinal Fractures and Fixation Techniques
- History of Medicine Studies
- Neuroendocrine Tumor Research Advances
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and Carotid Artery Diseases
- Spinal Dysraphism and Malformations
- Neurology and Historical Studies
- Ophthalmology and Eye Disorders
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Medical and Biological Sciences
- Functional Brain Connectivity Studies
Istituto delle Scienze Neurologiche di Bologna
2016-2025
University of Bologna
2009-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Institute of Neurological Sciences
2013-2024
Unidad de Cirugía Artroscópica
2019
Ospedale Bellaria
2011-2017
The Ohio State University
2014
Neurological Surgery
2014
The Ohio State University Wexner Medical Center
2014
University of Ferrara
2013
A Horse Is a Horse, of Course The history horse domestication is closely tied to the human society. Wade et al. (p. 865 ) report on sequencing and provide single nucleotide polymorphism map ( Equus caballus genome. Horses are member order perissodactyla (odd-toed animals with hooves). analysis reveals an evolutionarily new centromere equine chromosome 11 that displays properties immature but fully functioning devoid centromeric satellite sequence. findings clarify nature genetic diversity...
Despite their benign histological appearance, craniopharyngiomas can be considered a challenge for the neurosurgeon and possible source of poor prognosis patient. With widespread use endoscope in endonasal surgery, this route has been proposed over past decade as an alternative technique removal craniopharyngiomas.The authors retrospectively analyzed data from series 103 patients who underwent endoscopic approach at two institutions (Division Neurosurgery Università degli Studi di Napoli...
Objective and design A clinicopathological score has been proposed by Trouillas et al . to predict the evolution of pituitary adenomas. Aim our study was perform an independent external validation this identify other potential predictor post-surgical outcome. Methods The sample included 566 patients with adenomas, specifically 253 FSH/LH-secreting, 147 GH-secreting, 85 PRL-secreting, 72 ACTH-secreting 9 TSH-secreting tumours at least 3-year follow-up. Results In 437 cases, adenomas were...
OBJECTIVE In the past decade, role of endoscopic endonasal approach (EEA) has relevantly evolved for skull base tumors. this study, authors review their surgical experience with using an EEA in treatment clival chordomas, which are deep and infiltrative lesions, they highlight advantages limitations ventral approach. METHODS All consecutive cases chordoma treated between 1998 2015 at a single institution included study. Preoperative assessment consisted neuroimaging (MRI CT angiography...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has an impact also on neurosurgical training and education, especially in most affected countries. We surveyed Italian residents, asking them to provide a brief description analyze the situation they are experiencing how educational system reacted one of countries all over world.
Social media have become ubiquitous and their role in medicine is quickly growing. They provide an open platform by which members share educational material, clinical experiences, collaborate with equity.To characterize the of social neurosurgery, we analyzed metrics largest neurosurgical group (Neurosurgery Cocktail), collected relevant data about activities, impact risks this groundbreaking technology.We extracted Facebook from 60-day time sample, including users demographics other...
Transorbital neuroendoscopic surgery (TONES) is a group of approaches whose indications are expanding from orbital tumors to more complex skull base lesions. We analyzed the role endoscopic transorbital approach (eTOA) for spheno-orbital tumors, reporting results our clinical series and systematic review literature. All patients operated 2016 2022 in Institution tumor through an eTOA were included literature was performed. Our consists 22 (16 females, mean age: 57 ± 13 years). Gross removal...
This study evaluates a series of consecutive endoscopic endonasal odontoidectomies performed since 2008 in our center.The aim the was to analyze outcome and surgical technique enlighten advantages limitations this procedure.Odontoidectomy represents treatment choice selected cases basilar invagination. Transoral-transpharyngeal odontoidectomy is "gold standard" more experienced technique. Recently, approach has been proposed as an alternative route.All patients underwent pre- postoperative...
OBJECTIVE Imposter syndrome (IS) occurs when high-achieving individuals have a pervasive sense of self-doubt combined with fear being exposed as fraud, despite objective measures success. This is one the main causes burnout among professionals, threatening their mental health and general well-being. The prevalence severity IS neurosurgery residents young neurosurgeons has not been yet studied. primary outcomes this study were IS. METHODS An anonymous cross-sectional survey including both...
Pituitary neuroendocrine tumours (PitNET)s can be aggressive, thus presenting local invasion, postsurgical recurrence and/or resistance to treatment, responsible for significant morbidity. The study aimed at identifying prognostic factors of outcome using data-driven classification patients.Retrospective observational study.Clinicopathological and radiological data patients with PitNET treated via endoscopic endonasal surgery were collected. Tumour recurrence/progression progression-free...
To profile clinically non-aggressive and aggressive pituitary adenomas (PAs)/pituitary neuroendocrine tumours (PitNETs) carcinomas for somatic mutations epigenetic alterations of genes involved in cell proliferation/differentiation, microRNAs (miRNA)/long noncoding RNA (LncRNA)-post-transcriptional regulators therapy targets.Retrospective observational study.A total 64 41 PAs/PitNETs 6 treated by endoscopic surgery with ≥1-year follow-up were included. Somatic 17 DNA methylation 22 assessed....
Background/Objectives: Clivus metastases from distant neoplasms are uncommon occurrences both in clinical practice and the neurosurgical literature. Surgical management is debated, particularly about role of surgery preferable approach. The aim this study was to report our surgical experience review concerning Methods: Our institutional registry retrospectively reviewed, patients who underwent treatment for clival metastasis 1998 2023 were included. A PRISMA systematic literature performed....
OBJECTIVE Machine learning (ML) is an innovative method to analyze large and complex data sets. The aim of this study was evaluate the use ML identify predictors early postsurgical long-term outcomes in patients treated for Cushing disease (CD). METHODS All consecutive our center who underwent surgery CD through endoscopic endonasal approach were retrospectively reviewed. Study endpoints gross-tumor removal (GTR), remission, control disease. Several demographic, radiological, histological...
Glioblastoma represents the most lethal brain tumor in adults. Several studies have shown key role of phospholipase C β1 (PLCβ1) regulation many mechanisms within central nervous system suggesting PLCβ1 as a novel signature gene molecular classification high-grade gliomas. This study aims to determine pathological impact glioblastoma, confirming that expression correlates with glioma's grade, and it is lower 50 glioblastoma samples compared 20 healthy individuals. silencing cell lines...
Surgical guidance can be delivered in various ways. In neurosurgery, spatial and orientation are predominantly achieved through neuronavigation systems that reference pre-operative MRI scans. Recently, there has been growing interest providing live by analyzing video feeds from tools such as endoscopes. Existing approaches, including anatomy detection, feedback, phase recognition, visual question-answering, primarily focus on aiding surgeons assessing the current surgical scene. This work...