A5004218083- Soft Robotics and Applications
- Ultrasound and Hyperthermia Applications
- Advanced Radiotherapy Techniques
- Ultrasound Imaging and Elastography
- Photoacoustic and Ultrasonic Imaging
- Corneal surgery and disorders
- Optical Imaging and Spectroscopy Techniques
- Corneal Surgery and Treatments
- Medical Imaging and Analysis
- Ophthalmology and Visual Impairment Studies
- 3D Printing in Biomedical Research
- Advanced Vision and Imaging
- Innovative Microfluidic and Catalytic Techniques Innovation
- Teleoperation and Haptic Systems
- Robot Manipulation and Learning
- Ocular Infections and Treatments
- Cardiovascular Health and Disease Prevention
- Advanced MRI Techniques and Applications
- Bayesian Modeling and Causal Inference
- Cerebrovascular and Carotid Artery Diseases
Erasmus MC
2025
Thomas Jefferson University
2007-2008
Beihang University
2000-2006
Ultrasonography could allow operator-independent examination and continuous monitoring of the carotid artery, but normally requires complex expensive transducers, especially for 3D. By employing computational ultrasound imaging (cUSi), using an aberration mask model-based reconstruction, a device be constructed with more affordable simple transducer design comprising only few elements. We aim to apply cUSi concept create artery system. The system's possible configurations 2D case were...
The robotic system is developed to improve the effect of microsurgery for keratoplasty. autonomous suturing should be qualified operational requirements microsurgical Poorly modeled mechanism micromanipulator and slight movements surgical objective point are hindrance precise position orientation end-needle. Visual servo control available overcome these obstacles. An appropriate scheme vision proposed. On basis biological binocular vision, a feasible method calibration reconstruction...
Purpose: To investigate influence of different needle insertion and seed deposition techniques for robotic brachytherapy. find optimal sets low, normal high translational rotational velocities the decreasing force, deflection OR time, increasing placement accuracy. Method Materials: We have developed EUCLIDIAN — a fully automatic prostate brachytherapy system. Robotic system parameters were optimized via preclinical experiments using two types polyvinylchloride tissue phantoms, cannula...
Robotic system is developed to improve the effect of microsurgery for keratoplasty. Based on task and motion analysis in surgery, type synthesis size robotic mechanism are performed meet requirements surgical tasks. Force position microsensors integrated end-effector microsurgical robot. The two digital filtering methods suitable PC sensor data board respectively presented. A feasible method calibration reconstruction microscope adopted implement guidance vision. estimated coefficients by...
In a preclinical study, we demonstrated that blood flow and tissue oxygenation could be manipulated by focused ultrasound; the effects of such manipulation were interrogated via optical spectroscopy at wavelengths where oxy- deoxy-hemoglobin display different extinction properties. We have designed clinical breast scanner based on these noninvasive techniques. addition to ultrasound field intersecting with volume illumination points spectral collection, diagnostic quality imaging probe is...
Needle insertion in soft tissue has raised a lot of research interests lately. A spring-beam-damper model been developed for needle-tissue interaction. Considering the inhomogeneity, depth-varying mean parameters are proposed to calculate spring/damper reaction forces. Based on this approach, an online parameter estimator designed using modified least square method with forgetting factor. In paper, mathematical relationships efficient and robust needle tip trajectory prediction inhomogeneous...
Purpose: Focused ultrasonic radiation is known for its ability to induce thermal effects therapy deep in tissue without surgical intervention. To design a medium intensity focused ultrasound (MIFU) system with distributed transducers breast cancer therapy, physical properties of the acoustic field must be fully characterized. Method and Materials: Custom made driving were calibrated 1MHz sine wave input (1mW power). Calibrated gain RF amplifier was utilized power control. Numerical...
Purpose: To investigate the efficacy of using acoustic radiation force (ARF) combined with optical spectroscopy to assess early effects anti‐angiogenic therapy on changes in oxy‐hemoglobin saturation a human glioblastoma xenograft model. Method and Materials: Pilot experiments were carried out nude mice bearing U87 xenografts. Acoustic field intensities generated focused transducer operating below FDA diagnostic ultrasound limits. During each experiment, was administered for 5‐second bursts,...
Purpose: To perform calibration and evaluation of an image‐guided brachytherapy robotic system. Method Materials: Brachytherapy robot consists three steps: mechanical calibration, image overall system calibration. Mechanical determines 1)system resolution, as the smallest incremental movement that can physically perform, 2)repeatability a measure ability to move back same position orientation 3)accuracy, robot's precisely desired in 3D space. Imaging for our is procedure where distance from...