A5091083243- Advanced Fiber Optic Sensors
- Photonic and Optical Devices
- Plasmonic and Surface Plasmon Research
- Advanced Fiber Laser Technologies
- Photonic Crystal and Fiber Optics
- Advanced biosensing and bioanalysis techniques
- Advanced Biosensing Techniques and Applications
- Mechanical and Optical Resonators
- Biosensors and Analytical Detection
- Advanced Photonic Communication Systems
- Analytical Chemistry and Sensors
- Mosquito-borne diseases and control
- Electrochemical sensors and biosensors
- Advanced MEMS and NEMS Technologies
- Acoustic Wave Resonator Technologies
- Electrodeposition and Electroless Coatings
- Advanced Fluorescence Microscopy Techniques
- Malaria Research and Control
- Optical Network Technologies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Semiconductor Lasers and Optical Devices
- Complement system in diseases
- Pineapple and bromelain studies
- Phytoplasmas and Hemiptera pathogens
University of Mons
2016-2024
Washington University in St. Louis
2023-2024
The detection of circulating tumor cells (CTCs), which are responsible for metastasis in several forms cancer, represents an important goal oncological diagnosis and treatment. These remain extremely challenging to detect, despite numerous previous studies, due their low concentration (1–10 cells/mL blood). In this work, all-fiber plasmonic aptasensor featuring multiple narrowband resonances the near-infrared wavelength range was developed detect metastatic breast cancer cells. To aim,...
Measuring cortisol levels as a stress biomarker is essential in many medical conditions associated with high risk of metabolic syndromes such anxiety and cardiovascular diseases, among others. One technology that has growing interest recent years fiber optic biosensors enable ultrasensitive detection. Such allied progress being achieved basic interrogation, accuracy improvements, novel applications. The development improved monitoring, simplified manufacturing process, reproducibility, low...
Cortisol is a stress biomarker whose chronic elevated levels are associated with higher risk of metabolic syndromes, anxiety, and cardiovascular diseases, among other medical conditions. A new immunosensor based on plasmonic tilted fiber Bragg grating (TFBG) has been developed tested for rapid ultrasensitive cortisol detection. The gold coated TFBG was characterized to surrounding refractive index (SRI) changes functionalized anti-cortisol antibodies via cysteamine. functionalization...
The aim of this paper is to provide a comprehensive review mode-division and spatial-division optical fiber sensors, mainly encompassing interferometers advanced gratings. Compared with their single-mode counterparts, which have very mature field many highly successful commercial applications, multimodal configurations developed more recently advances in device fabrication novel mode control devices. Multimodal sensors considerably widen the range possible sensing modalities opportunities...
In the biomedical detection context, plasmonic tilted fiber Bragg gratings (TFBGs) have been demonstrated to be a very accurate and sensitive sensing tool, especially well-adapted for biochemical detection. this work, we developed an aptasensor following triple strategy improve overall performances robustness. Single polarization (SPF) is used as biosensor substrate while demodulation based on tracking peculiar feature of lower envelope cladding mode resonances spectrum. This method highly...
Gold-coated tilted fiber Bragg gratings (TFBGs) have been highly studied over the last years, mainly for biosensing purposes. They present a comb-like spectrum of narrow-band cladding mode resonances that is often demodulated by tracking change selected peak. In this paper, we report twentyfold more sensitive demodulation method based on intersection upper and lower envelopes gold-coated TFBG spectra. This has successfully applied in experiments towards detection HER2 (Human Epidermal Growth...
Spectral multiplexing of biosensors in a single optical fiber has been long-standing challenge, which we address here for the first time by combining photonic crystal fibers (PCF) with Bragg grating technology. We exploit features transmission spectrum straight written PCF that allows exciting cladding mode resonances within spectral span about 60 nm, is significantly narrower than width spectra tilted gratings standard single-mode step-index fibers. More specifically, consider feature...
Optical fiber gratings have widely proven their applicability in biosensing, especially when they are coupled with antibodies for specific antigen recognition. While this is customarily done fibers coated by a thin metal film to benefit from plasmonic enhancement, paper, we propose study intrinsic properties, developing label-free sensor the detection of biomarkers real-time without coatings surface plasmon resonances. We focus on inner properties our modal immobilizing receptors directly...
Gold-coated fiber Bragg gratings (FBGs) are nowadays a mature technology for lab-on-fiber sensing based on surface plasmon resonance (SPR) excitation. Tilted FBGs bring valuable assets such as easy light injection, remote operation in very small volumes of analytes and immunity to temperature fluctuations. Different gold configurations have been reported date, without considering their relative performances terms biochemical sensing. In this work, we experimentally study the impact coating...
Abstract The precise measurement of surface refractive index changes is crucial in biosensing, providing insights into bioreceptors–analytes interactions. However, correlating intricate spectral features, with these variations remains a persistent challenge, particularly optical fiber gratings-based Surface Plasmon Resonance sensing. Here, we introduce machine learning-based approach to address this ongoing issue. We integrate regression model gold-coated tilted Bragg grating sensors. This...
Surface plasmon resonance excitation with optical fiber gratings has been typically studied in aqueous solutions. This work describes the procedure to excite a wave gaseous media and perform refractive index measurements these environments. Grating photo-inscription 193 nm excimer laser radiation allows us obtain slightly tilted Bragg exhibiting cladding mode comb along several hundreds of nanometers. Their sensitive range extends from gases liquids, so operation both is compared. We...
Optical fibers are of growing interest for biosensing, especially point-of-care and biomedical assays. Their intrinsic properties bestow them sought-after assets the detection low concentrations analytes. Tilted fiber Bragg gratings (TFBGs) photo-inscribed in core telecommunication-grade optical known to be highly-sensitive refractometers. In this work, we present different strategies use label-free immunoassays. Bare, gold-sputtered, gold-electroless-plated (ELP) hybrid configurations...
Tilted fiber Bragg gratings (TFBGs) are now a well-established technology in the scientific literature, bringing numerous advantages, especially for biodetection. Significant sensitivity improvements achieved by exciting plasmon waves on their metal-coated surface. Nowadays, large part of advances this topic relies new strategies aimed at providing enhancements. In work, TFBGs produced both single-mode and multimode telecommunication-grade optical fibers, relative performances evaluated...
Bare and gold-coated tilted fiber Bragg gratings (TFBGs) can nowadays be considered as a mature technology for volume surface refractometric sensing, respectively. As other technologies, continuous effort is made towards the production of even more sensitive sensors, thereby enabling high-resolution screening surroundings possible detection rare events. To this aim, we study in work development TFBG refractometers 4-core fibers. In particular, show that sensitivity cut-off mode reach 100...
Heart failure (HF) is a clinical entity included in cardiovascular diseases affecting millions of people worldwide, being leading cause hospitalization older adults, and therefore imposing substantial economic burden on healthcare systems. HF characterized by dyspnea, fatigue, edema associated with elevated blood levels natriuretic peptides, such as N Terminal pro-B-type Natriuretic Peptide (NT-proBNP), for which there high demand point care testing (POCT) devices. Optical fiber (OF)...