A5073844293- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Dental materials and restorations
- biodegradable polymer synthesis and properties
- Facial Trauma and Fracture Management
- Laser-Ablation Synthesis of Nanoparticles
- Electrospun Nanofibers in Biomedical Applications
- Periodontal Regeneration and Treatments
- Orthopaedic implants and arthroplasty
- Collagen: Extraction and Characterization
- Additive Manufacturing and 3D Printing Technologies
- Hydrogels: synthesis, properties, applications
- Graphene and Nanomaterials Applications
- Polymer Surface Interaction Studies
- Bone Metabolism and Diseases
- Dental Erosion and Treatment
- Bone and Dental Protein Studies
- COVID-19 Clinical Research Studies
- Spine and Intervertebral Disc Pathology
- Chemical Synthesis and Characterization
- Polymer composites and self-healing
- Luminescence Properties of Advanced Materials
- Laser Applications in Dentistry and Medicine
- Wound Healing and Treatments
- Bone health and osteoporosis research
Universidade Federal de Minas Gerais
2016-2025
Universidade Federal de Lavras
2023
Louisiana State University Health Sciences Center New Orleans
2017
John Wiley & Sons (United States)
2017
Texas A&M University
2017
Smith College
2017
Syracuse University
2017
University of Memphis
2017
Imperial College London
2005
University of Florida
1994-1995
Abstract When soluble salts are used in the sol‐gel processing of bioactive glasses, resulting materials not homogeneous. To produce homogeneous gel‐glasses, a method using all alkoxide precursors was developed. In this work vitro bioactivity new all‐alkoxide gel‐glasses is investigated. Three compositions system, CaOP 2 O 5 SiO , were studied. Solid samples soaked Tris buffer and simulated body fluid (SBF), rate formation hydroxy carbonate apatite (HCA) on surface glasses measured by...
An apatite layer can be formed on pure gel‐silica soaked in simulated body fluid. The rate of formation depends solution parameters and sintering temperature the gelsilica. In this study, effect texture hydroxyapatite was investigated. monitored by means Fourier‐transform infrared reflection spectroscopy as well measurement changes ion concentration induction time for nucleation gel silica decreased pore size volume increased. substrate that affect are discussed a mechanism assumes pores...
AbstractAbstractTissue engineering is an important technique for regenerating diseased or damaged tissues. In tissue engineering, a highly porous artificial extracellular matrix scaffold required to accommodate cells and guide their growth regeneration in three dimensions. The choice of scaffolding material crucial the success technique. Bioactive glasses are option as bone owing recognised osteoconductive osteoinductive properties controllable degradation rate. Resorbable 3D macroporous...
Nanotechnology offers a new strategy to develop novel bioactive materials, given that nano-scaled biomaterials exhibit an enhanced biocompatibility and bioactivity. In this work, we developed method for the synthesis of spherical glass nanoparticles (BGNP) aimed at producing potential use in repair hard tissues. The BGNP were prepared using sol–gel process based on reaction alkoxides other precursors aqueous media obtaining oxide-ternary system with stoichiometric proportion 60% SiO2, 36%...
The emergence of life-threatening zoonotic diseases caused by betacoronaviruses, including the ongoing coronavirus disease 19 (COVID-19) pandemic, has highlighted need for developing preclinical models mirroring respiratory and systemic pathophysiological manifestations seen in infected humans. Here, we showed that C57BL/6J wild-type mice intranasally inoculated with murine betacoronavirus hepatitis 3 (MHV-3) develop a robust inflammatory response leading to acute lung injuries, alveolar...
Bioactive glass nanoparticles (BGNPs) are of great interest in tissue engineering as they possess high dissolution rate and capability being internalized by cells, releasing their products with therapeutic benefits intracellularly. A modified Stöber process can be applied to obtain different BGNPs compositions containing ions while maintaining controllable particle morphology, monodispersity reduce agglomeration. Here, Mn, an ion that has been shown influence the osteoblast proliferation...
The biomaterials research field has broadened in the last 3 decades, including replacement of diseased or damaged parts, assist healing, correct and improve functional abnormality, drug delivery systems, immunological kits biosensors. Proteins play crucial role almost every biological system. They are involved enzymatic catalysis, transport storage, coordinated motion, mechanical support, immune protection, control growth cell differentiation among many others. immobilization proteins onto...
Abstract Well‐defined structural characteristics are some of the exigencies that have to be attended when scaffolds for bone tissue cell culture designed. A high porosity (70–90%) and a specific surface area an average pore size > 150 μm will contribute allow migration throughout structure, adhesion, proliferation. At same time, biodegradation material should occur in proper rate. One way reach structure with these is produce foams during sol–gel processing bioactive glasses (system...
Glutamate released by osteoblasts sharing similarities with its role in neuronal transmission is a very new scientific concept which actually changed the understanding of bone physiology. Since glutamate release calcium (Ca(2+))-dependent process and considering that we have previously demonstrated dissolution bioactive glass 60% silicon (BG60S) can alter osteoblast Ca(2+)-signaling machinery, investigated whether BG60S induces secretion it requires an increase intracellular Ca(2+). Here...
Cementum is a mineralized tissue that lines the surface of tooth root enabling attachment periodontal ligament to and surrounding alveolar bone. Studies examining mechanisms involved in formation cementum have been hindered by an inability isolate culture cells required for production (cementoblasts). This study isolated characterized cementoblast derived from rat molar ligament. It was observed expressed F-Spondin, marker, while F-Spondin expression not other tissues such as gingival...